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Othniel Sintim

I work as teaching assistant in clinical physiology and histology. In addition, I work as a research assistant. My research explores the role of neutrophils in coronary artery disease and atherosclerosis.


Neutrophils in coronary artery disease

Coronary artery disease (CAD) is the number one disease-related cause of death in the world. It is the main manifestation of atherosclerosis and the most common cause of myocardial infarction (MI).

Inflammation is a well-recognized key driver of CAD. Of note, CAD patients suffer chronic low-grade inflammation even under today’ s optimal treatment (including high-dose statin). This is known to increase the risk of recurrent coronary events, the so-called “residual inflammatory risk”. A key driver in this sustained inflammation are neutrophil. My research focuses on how neutrophil activity affects disease progression in CAD.

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