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Per Hammarström

Professor

News

Electron microscopy image showing amyloid of corona virus spike protein.

Possible discovery of mechanism behind mysterious COVID-19 symptoms

The immune system can affect the SARS-CoV-2 spike protein, leading to the production of a misfolded spike protein called amyloid. A new study points to a possible connection between harmful amyloid production and symptoms of COVID-19.
Pipette in chemistrylab.

Master’s programme in protein science now open for international students

Linköping University will open its Protein Science master’s programme to international students starting next year. The programme combines theoretical and practical components, with a heavy emphasis on laboratory work.
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Alzheimer plaque affects different brain cells differently

Amyloid beta, a protein linked with Alzheimer's disease, has different properties in different cell types in the brains of fruit flies, according to a new study. It seems that certain cell types are hardly damaged at all by amyloid aggregates.

Organisation

Chemistry (KEMI)

The division's research is being performed in the areas of biochemistry, molecular biotechnology, organic chemistry, analytical chemistry, chemical engineering, inorganic chemistry and in physical chemistry, especially computational chemistry.

Department of Physics, Chemistry and Biology (IFM)

Undergraduate teaching and research in the areas of biology, chemistry, materials and applied physics and theory and modelling are conducted at this department.

Research

teaser image Hammarström lab

Hammarström Lab

We are interested in protein misfolding, amyloid formation and disease, both on the molecular level and in the cellular perspective.
Campus US with cherry blossom in the foreground.

SciLifeLab Linköping

SciLifeLab Linköping is both a local and a national research infrastructure, with unique technologies and expert competence accessible for academic and industrial researcher in the field of life sciences, health and data-driven life science.

Publications

2025

Farjana Parvin, Johan Larsson, Walker Jackson, Sofie Nyström, Per Hammarström (2025) Efficient Seeding of Cerebral Vascular Ab-Amyloidosis by Recombinant AbM1-42 Amyloid Fibrils Journal of Molecular Biology, Vol. 437, Article 168923 (Article in journal) Continue to DOI
Gunilla T. Westermark, Ebba Nystrom, Sofie Nyström, Peter Nilsson, Per Hammarström, Per Westermark (2025) The question of strains in AA amyloidosis Scientific Reports, Vol. 15, Article 3684 (Article in journal) Continue to DOI
Therése Klingstedt, Hamid Shirani, Farjana Parvin, Sofie Nyström, Per Hammarström, Caroline Graff, Martin Ingelsson, Ruben Vidal, Bernardino Ghetti, Dag Sehlin, Stina Syvanen, Peter Nilsson (2025) Dual-ligand fluorescence microscopy enables chronological and spatial histological assignment of distinct amyloid-b deposits Journal of Biological Chemistry, Vol. 301, Article 108032 (Article in journal) Continue to DOI
Marikken Sundnes, Priyanka Swaminathan, Mikael Lindgren, Ganesh Mohite, Ebba Hellstrand, Sofie Nyström, Per Hammarström (2025) The Fluorescent Amyloid Ligand X34 Binding to Transthyretin (TTR) Tetramer and Fibrils: FRET and Binding Constants of a Sequential Two-step Process ChemPhotoChem, Vol. 9, Article e202400249 (Article in journal) Continue to DOI

2024

Priyanka Swaminathan, Therése Klingstedt, Vasileios Theologidis, Hjalte Gram, Johan Larsson, Lars Hagen, Nina B. Liabakk, Odrun A. Gederaas, Per Hammarström, Peter Nilsson, Nathalie van den Berge, Mikael Lindgren (2024) In Vitro Cell Model Investigation of Alpha-Synuclein Aggregate Morphology Using Spectroscopic Imaging International Journal of Molecular Sciences, Vol. 25, Article 12458 (Article in journal) Continue to DOI

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