Photo of Rozalyn Simon

Rozalyn Simon

Associate Professor

Neuroimaging research interests include investigating the brain-gut-microbiome axis in relation to fMRI connectivity and meditation as a modulator of brain function. Rozalyn is also Director of the Forum Scientium graduate research school.

Presentation

Rozalyn Simon began her higher education studies with a self-designed pre-medical bachelor’s curriculum incorporating medicinal botany, anthropology, and psychology (BSc 2001, University of Georgia, Athens, USA). In 2003, she began her graduate work in the chemistry department at the University of California, Santa Cruz. There, she joined the laboratory of Scott Lokey, focusing on the synthesis and analysis of novel small molecule libraries for inhibition of metabolic pathways in cancerous cells. In 2007, she received her Master’s in Chemistry and Biochemistry.

Later that year, she moved to Sweden, and began her PhD studies in chemistry at Linköping University in the group of Peter Nilsson. Her research focused on synthesis of small molecules (oligothiophenes) for detection and classification of protein plaques in amyloid related diseases such as Alzheimer’s. In 2014, she received her PhD. 

During her PhD studies, she became increasingly intrigued by the psychological aspects associated with amyloid related diseases such as Alzheimer’s, and the anatomy and neurofunction underlying the "loss of self". She thus chose to follow the AD/neuroscience aspects of her PhD toward more direct clinical applications. To this end, she shifted focus into fMRI techniques and was awarded a postdoctoral fellowship at Linköping University’s Center for Medical Image Science and Visualization (CMIV) to study the neural correlates of meditative practice in neurodegenerative disorders. 

In 2017, she began her Assistant Professorship at Linköping University, focusing on neuroimaging techniques to investigate brain function in relation to meditative practices in neurodegenerative disease, and the gut-brain-microbiota axis in disorders such as IBS, in an effort to better understand the interplay between physiological and cognitive mechanisms in disease states. Particular areas of interest include brain-gut-microbiota interactions as well as the neural correlates behind successful therapeutic cognitive interventions such as hypnotherapy and meditation.

In 2020, Rozalyn became Director of the Forum Scientium graduate research school at Linköping University.




Research and work

CV

Education

2014 – PhD in Chemistry, Linköping University

2007 – Masters in Chemistry and Biochemistry, University of California, Santa Cruz

2001 – Bachelors in Science, self-designed interdisciplinary pre-medical degree with focus on medicinal botany, anthropology, and psychology. University of Georgia, Athens


Positions

2020-present – Director, Forum Scientium graduate research school

2020-present – Associate Professor, Division of Radiological Sciences and CMIV, LiU

2020-2021 – Clinical Science Lead, AMRA Medical AB (50% position)

2017-2020 – Assistant Professor, Division of Radiological Sciences and CMIV, LiU

2015-2017 – Postdoctoral Researcher, CMIV, LiU


Publications

2023

Shirin Ilkhanizadeh, Aileen Gracias, Andreas Åslund, Markus Bäck, Rozalyn Simon, Edel Kavanagh, Bianca Migliori, Christina Neofytou, Sven Nelander, Bengt Westermark, Lene Uhrbom, Karin Forsberg-Nilsson, Peter Konradsson, Ana I. Teixeira, Per Uhlen, Bertrand Joseph, Ola Hermanson, Peter Nilsson (2023) Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative ACS Applied Bio Materials, Vol. 6, p. 3790-3797 (Article in journal) Continue to DOI

2022

Dennis van der Meer, Tiril P. Gurholt, Ida E. Sonderby, Alexey A. Shadrin, Guy Hindley, Zillur Rahman, Ann-Marie G. de Lange, Oleksandr Frei, Olof Dahlqvist Leinhard, Jennifer Linge, Rozalyn Simon, Dani Beck, Lars T. Westlye, Sigrun Halvorsen, Anders M. Dale, Tom H. Karlsen, Tobias Kaufmann, Ole A. Andreassen (2022) The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition Communications Biology, Vol. 5, Article 1271 (Article in journal) Continue to DOI
Dennis van der Meer, Tiril P. Gurholt, Ida E. Sønderby, Alexey A. Shadrin, Guy Hindley, Zillur Rahman, Ann-Marie G. de Lange, Oleksandr Frei, Olof Dahlqvist Leinhard, Jennifer Linge, Rozalyn Simon, Lars T. Westlye, Sigrun Halvorsen, Anders M. Dale, Tom H. Karlsen, Tobias Kaufmann, Ole A. Andreassen (2022) The role of liver fat in cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition
Nawroz Barazanji, Paul J. Hamilton, Adriane Icenhour, Rozalyn Simon, Olga Bednarska, Sofie Tapper, Anders Tisell, Peter Lundberg, Maria Engström, Susanna Walter (2022) Irritable bowel syndrome in women: Association between decreased insular subregion volumes and gastrointestinal symptoms NeuroImage: Clinical, Vol. 35, Article 103128 (Article in journal) Continue to DOI
Dani Beck, Ann-Marie G. De Lange, Dag Alnaes, Ivan I. Maximov, Mads L. Pedersen, Olof Dahlqvist Leinhard, Jennifer Linge, Rozalyn Simon, Genevieve Richard, Kristine M. Ulrichsen, Erlend S. Dorum, Knut K. Kolskår, Anne-Marthe Sanders, Adriano Winterton, Tiril P. Gurholt, Tobias Kaufmann, Nils Eiel Steen, Jan Egil Nordvik, Ole A. Andreassen, Lars T. Westlye (2022) Adipose tissue distribution from body MRI is associated with cross-sectional and longitudinal brain age in adults NeuroImage: Clinical, Vol. 33, Article 102949 (Article in journal) Continue to DOI
Maria Engström, Johan Willander, Rozalyn Simon (2022) A Review of the Methodology, Taxonomy, and Definitions in Recent fMRI Research on Meditation Mindfulness, Vol. 13, p. 541-555 (Article, review/survey) Continue to DOI

2021

Rozalyn Simon, Purnika Ranasinghe, Nawroz Barazanji, Malin Bergman Jungeström, Jie Xu, Olga Bednarska, Lena Serrander, Maria Engström, Dennis A. Bazylinski, Åsa Keita, Susanna Walter (2021) Magnetotactic bacteria from the human gut microbiome associated with orientation and navigation regions of the brain Journal of Oceanology and Limnology, Vol. 39, p. 2044-2052 (Article in journal) Continue to DOI