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Sarah Lindström

Principal Research Engineer

Research

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Stopping the propagation of neurodegenerative diseases like Alzheimer’s and Parkinson’s

Neurodegenerative disease like Alzheimer's and Parkinson’s are progressive disease that causes great suffering for the victims and relatives, in addition it cause large economic costs for society.
a coarse brush is applied to the back of the hand

The Nagi Lab

Pain in the ultrafast lane. We are interested in better understanding the peripheral nervous system’s role in acute and persistent pain using microneurography.

Publications

2023

Teresa Mínguez‐Viñas, Varsha Prakash, Kaiqian Wang, Sarah Lindström, Serena Pozzi, Stuart A. Scott, Elizabeth Spiteri, David A. Stevenson, Euan A. Ashley, Cecilia Gunnarsson, Antonios Pantazis (2023) Two epilepsy‐associated variants in KCNA2 (KV1.2) at position H310 oppositely affect channel functional expression Journal of Physiology, Vol. 601, p. 5367-5389 (Article in journal) Continue to DOI

2022

Michelle Nilsson, Sarah H Lindström, Maki Kaneko, Kaiqian Wang, Teresa Minguez-Viñas, Marina Angelini, Federica Steccanella, Deborah Holder, Michela Ottolia, Riccardo Olcese, Antonios Pantazis (2022) An epilepsy-associated KV1.2 charge-transfer-center mutation impairs KV1.2 and KV1.4 trafficking Proceedings of the National Academy of Sciences of the United States of America, Vol. 119 (Article in journal) Continue to DOI

2020

Antonios Pantazis, Maki Kaneko, Marina Angelini, Federica Steccanella, Annie M. Westerlund, Sarah Lindström, Michelle Nilsson, Lucie Delemotte, Sulagna C. Saitta, Riccardo Olcese (2020) Tracking the motion of the K(V)1.2 voltage sensor reveals the molecular perturbations caused by ade novomutation in a case of epilepsy Journal of Physiology, Vol. 598, p. 5245-5269 (Article in journal) Continue to DOI
Sarah Lindström, Sofie Sundberg, Max Larsson, Fredrik K. Andersson, Jonas Broman, Björn Granseth (2020) VGluT1 Deficiency Impairs Visual Attention and Reduces the Dynamic Range of Short-Term Plasticity at Corticothalamic Synapses Cerebral Cortex, Vol. 30, p. 1813-1829 (Article in journal) Continue to DOI

2018

Anna Klawonn, Daniel Wilhelms, Sarah Lindström, Anand Kumar Singh, Maarit Jaarola, Jurgen Wess, Michael Fritz, David Engblom (2018) Muscarinic M4 Receptors on Cholinergic and Dopamine D1 Receptor-Expressing Neurons Have Opposing Functionality for Positive Reinforcement and Influence Impulsivity Frontiers in Molecular Neuroscience, Vol. 11, Article 139 (Article in journal) Continue to DOI

Organisation

The Division of Cell and Neurobiology (CNB)

The Division of Cell and Neurobiology is a dynamic and innovative environment where we conduct research and teaching on both the structure and function of various cells as well as the nervous system and sensory organs.

Department of Biomedical and Clinical Sciences (BKV)

What characterizes the Department of Biomedical and Clinical Sciences (BKV) is the wide breadth of research and education. BKV is one of the largest departments at LiU with affiliation mainly to the Faculty of Medicine and Health Sciences.

News

Kaiqian Wang.

A subtle genetic change gives new clues about epilepsy

Sometimes, even the alteration of a single nucleotide in a gene can cause serious disease. A recent study sheds light on the molecular biology behind some forms of genetic epilepsy.

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