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Stergios Kechagias

Professor

Professor in internal medicine

Research on metabolic dysfunction-associated steatotic liver disease (MASLD)

MASLD has become the most common liver disease affecting adults and children.

Our research purposes are to further characterize the natural history of MASLD, identify factors that influence the progression of MASLD, and to develop and validate diagnostic methods for MASLD.

Publications

2026

Heather Collis, Sara F. Hansson, Patrik Nasr, Cecilia Jönsson, Mathias Liljeblad, Bjorn Carlsson, Showgy Ma'ayeh, Boxi Zhang, Jana de Wiljes, Mattias Ekstedt, Stergios Kechagias, Jane Knochel (2026) Discovery of Epidermal Growth Factor-Like 7 as a Potential Non-Invasive Biomarker for Fibrosis and Mortality Risk in MASLD Clinical and Translational Science, Vol. 19, Article e70716 (Article in journal) https://dx.doi.org/10.1111/cts.70716
Kim Ahtola, Martin Ulander, Jonas Agholme, Farida Amiri, Pontus Henriksson, Olof Dahlqvist Leinhard, Peter Lundberg, Nils Dahlström, Carljohan Carlhäll, Stergios Kechagias, Patrik Nasr, Mikael Forsgren, Mattias Ekstedt, Fredrik Iredahl (2026) Associations between fat distribution and obstructive sleep apnea severity among individuals with type 2 diabetes: an MRI-based study Scientific Reports, Vol. 16, Article 19329 (Article in journal) https://dx.doi.org/10.1038/s41598-026-58058-0
Helena Skroder, Mattias Ekstedt, Stergios Kechagias, Riku Ota, Ying Shang, Fotis Tefos, Emilie Toresson Grip, Johan Vessby, Hannes Hagstrom (2026) Comorbid type 2 diabetes and cardiovascular disease drive higher healthcare costs in MASLD/MASH: a retrospective Swedish cohort study Scandinavian Journal of Gastroenterology, Vol. 61, p. 1117-1128 (Article in journal) https://dx.doi.org/10.1080/00365521.2026.2698838
Wolf Bartholomä, Shan Cai, Christian Simonsson, Markus Karlsson, Stergios Kechagias, Mischa Woisetschläger, Nils Dahlström, Peter Lundberg (2026) Pharmacokinetic modelling of MRI-based liver function for risk assessment in primary sclerosing cholangitis: a prospective pilot study European Radiology Experimental, Vol. 10, Article 91 (Article in journal) https://dx.doi.org/10.1186/s41747-026-00764-5
Sara F. Hansson, Patrik Nasr, Jane Knochel, Tasso Miliotis, Anne-Christine Andreasson, Andreas Hober, Ann-Christin Nyström, Linnea Bergenholm, Mahssa Karimi, Xiao-Rong Peng, Mattias Ekstedt, Stergios Kechagias, Mathias Liljeblad (2026) Fibroblast activation protein and down-stream effects on its substrates in metabolic dysfunction-associated steatotic liver disease Scandinavian Journal of Gastroenterology, Vol. 61, p. 976-987 (Article in journal) https://dx.doi.org/10.1080/00365521.2026.2679101

News

Mattias Ekstedt, Nils Dahlström, Peter Lundberg, Bengt Norén and Patrik Nasr.

Liver examinations without needles

How is your liver doing? Decades of research into the use of magnet resonance imaging is now being put to work to gain information about patients’ livers – without needles.

European project to develop better tests for liver disease

A large European research project aims to develop better diagnostics to predict which patients with non-alcoholic fatty liver disease run the highest risk of developing severe disease.
Microscopy image of fat in the liver.

Magnetic resonance finds fatty liver

Taking tissue samples to diagnose fatty liver can be replaced in most cases by a painless magnetic resonance investigation, according to a new study.

Research group

Bild på utsnitt av fettlever

Metabolic dysfunction-associated steatotic liver disease (MASLD)

Metabolic dysfunction-associated steatotic liver disease (MASLD) previously known as non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease which has become the most common liver disease affecting adults and children.

Publications

Selected publications

image from publication
Patrik Nasr, Mikael F. Forsgren, Simone Ignatova, Nils Dahlström, Gunnar Cedersund, Olof Dahlqvist Leinhard, Bengt Norén, Mattias Ekstedt, Peter Lundberg, Stergios Kechagias (2017)
Using a 3% Proton Density Fat Fraction as a Cut-off Value Increases Sensitivity of Detection of Hepatic Steatosis, Based on Results from Histopathology Analysis

Gastroenterology , Vol.153 , s.53-+

Continue to DOI

Mattias Ekstedt, Hannes Hagström, Patrik Nasr, Mats Fredrikson, Per Stål, Stergios Kechagias, Rolf Hultcrantz (2015)
Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up

Hepatology , Vol.61 , s.1547-1554

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Stergios Kechagias, Åsa Ernersson, Olof Dahlqvist Leinhard, Peter Lundberg, Torbjörn Lindström, Fredrik Nyström, Toste Länne (2008)
Fast-food-based hyper-alimentation can induce rapid and profound elevation of serum alanine aminotransferase in healthy subjects

Gut , Vol.57 , s.649-654

Continue to DOI

Recent publications

2026

Heather Collis, Sara F. Hansson, Patrik Nasr, Cecilia Jönsson, Mathias Liljeblad, Bjorn Carlsson, Showgy Ma'ayeh, Boxi Zhang, Jana de Wiljes, Mattias Ekstedt, Stergios Kechagias, Jane Knochel (2026) Discovery of Epidermal Growth Factor-Like 7 as a Potential Non-Invasive Biomarker for Fibrosis and Mortality Risk in MASLD Clinical and Translational Science, Vol. 19, Article e70716 (Article in journal) https://dx.doi.org/10.1111/cts.70716
Kim Ahtola, Martin Ulander, Jonas Agholme, Farida Amiri, Pontus Henriksson, Olof Dahlqvist Leinhard, Peter Lundberg, Nils Dahlström, Carljohan Carlhäll, Stergios Kechagias, Patrik Nasr, Mikael Forsgren, Mattias Ekstedt, Fredrik Iredahl (2026) Associations between fat distribution and obstructive sleep apnea severity among individuals with type 2 diabetes: an MRI-based study Scientific Reports, Vol. 16, Article 19329 (Article in journal) https://dx.doi.org/10.1038/s41598-026-58058-0
Helena Skroder, Mattias Ekstedt, Stergios Kechagias, Riku Ota, Ying Shang, Fotis Tefos, Emilie Toresson Grip, Johan Vessby, Hannes Hagstrom (2026) Comorbid type 2 diabetes and cardiovascular disease drive higher healthcare costs in MASLD/MASH: a retrospective Swedish cohort study Scandinavian Journal of Gastroenterology, Vol. 61, p. 1117-1128 (Article in journal) https://dx.doi.org/10.1080/00365521.2026.2698838
Wolf Bartholomä, Shan Cai, Christian Simonsson, Markus Karlsson, Stergios Kechagias, Mischa Woisetschläger, Nils Dahlström, Peter Lundberg (2026) Pharmacokinetic modelling of MRI-based liver function for risk assessment in primary sclerosing cholangitis: a prospective pilot study European Radiology Experimental, Vol. 10, Article 91 (Article in journal) https://dx.doi.org/10.1186/s41747-026-00764-5
Sara F. Hansson, Patrik Nasr, Jane Knochel, Tasso Miliotis, Anne-Christine Andreasson, Andreas Hober, Ann-Christin Nyström, Linnea Bergenholm, Mahssa Karimi, Xiao-Rong Peng, Mattias Ekstedt, Stergios Kechagias, Mathias Liljeblad (2026) Fibroblast activation protein and down-stream effects on its substrates in metabolic dysfunction-associated steatotic liver disease Scandinavian Journal of Gastroenterology, Vol. 61, p. 976-987 (Article in journal) https://dx.doi.org/10.1080/00365521.2026.2679101

About me

CV

  • Reg. Physician 1996
  • PhD 2001
  • Professor 2013

Teaching

  • The Medical Program

Awards

  • Pedagogue of the Year, 2017
  • Bergdahl Award, 2022

Organisation

Close up of three doctors dressed in surgical clothes. One stands with his back to the camera.

Division of Diagnostics and Specialist Medicine (DISP)

The division consists of three units (internal medicine, cardiovascular and radiological sciences) and contains seven subject areas within which research and teaching are conducted.
Illustration of the letters HMV

Department of Health, Medicine and Caring Sciences (HMV)

The research areas at HMV include experimental basic research to clinical, social and public health research. We conduct high-quality education in the sought-after care professions.
Five people in a laboratory.

Faculty of Medicine and Health Sciences (MEDFAK)

The Faculty of Medicine and Health Sciences conducts research and education within medicine, healthcare and public health.