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Stergios Kechagias

Professor

Professor in internal medicine

Research on metabolic dysfunction-associated steatotic liver disease (MASLD)

MASLD has become the most common liver disease affecting adults and children.

Our research purposes are to further characterize the natural history of MASLD, identify factors that influence the progression of MASLD, and to develop and validate diagnostic methods for MASLD.

Publications

2026

Magnus Holmer, Michael Ingre, Martti Farkkila, Cyriel Ponsioen, Bregje Mol, Christoph Schramm, Trine Folseraas, Kristine Wiencke, Nora Cazzagon, Elisa Catanzaro, Antonio Molinaro, Emma Nilsson, Johan Vessby, Stergios Kechagias, Nils Nyhlin, Marten Werner, Annika Bergquist (2026) Cirrhosis and age are key determinants of HCC risk in individuals with primary sclerosing cholangitis: A multicenter longitudinal cohort study Hepatology, Vol. 83 (Article in journal) Continue to DOI
Ángel Herraiz-Adillo, Karin Rådholm, Fredrik Iredahl, Carljohan Carlhäll, Nahuel Roemkens, Mikael Forsgren, Olof Dahlqvist Leinhard, Peter Lundberg, Stergios Kechagias, Nils Dahlström, Patrik Nasr, Mattias Ekstedt, Pontus Henriksson (2026) Validity of the International Fitness Scale (IFIS) and its associations with cardiometabolic health and body composition in adults with type 2 diabetes: A cross-sectional study PLOS ONE, Vol. 21, Article e0339364 (Article in journal) Continue to DOI

2025

Magnus Holmer, Michael Ingre, Martti Farkkila, Cyriel Ponsioen, Bregje Mol, Christoph Schramm, Trine Folseraas, Kristine Wiencke, Nora Cazzagon, Elisa Catanzaro, Antonio Molinaro, Emma Nilsson, Johan Vessby, Stergios Kechagias, Nils Nyhlin, Marten Werner, Annika Bergquist (2025) Reply: Competing risk and surveillance thresholds for HCC in patients with PSC Hepatology, Article PMID 8302946 (Article in journal) Continue to DOI
Grazia Pennisi, Gabriele Di Maria, Vincent Wai-Sun Wong, Victor de Ledinghen, Giada Sebastiani, Mauro Vigano, Anna Ludovica Fracanzani, Luca Miele, Elisabetta Bugianesi, Mattias Ekstedt, Roberta D'Ambrosio, Federico Ravaioli, Filippo Schepis, Fabio Marra, Alessio Aghemo, Gianluca Svegliati-Baroni, Marcello Persico, Luca Valenti, Annalisa Berzigotti, Jacob George, Angelo Armandi, Patrik Nasr, Stergios Kechagias, Antonio Liguori, Dario Saltini, Yuly P. Mendoza, Vincenza Calvaruso, Marco Enea, Huapeng Lin, Giuseppe Infantino, Mario Masarone, Nicola Pugliese, Adele Tulone, Vito Di Marco, Calogero Camma, Salvatore Petta (2025) Impact of first and further decompensation in patients with compensated ACLD due to MASLD Journal of Hepatology, Vol. 83, p. 1266-1277 (Article in journal) Continue to DOI
Martin Bergram, Stergios Kechagias, Fredrik Iredahl, Wile Balkhed, Markus Holmberg, Nils Dahlström, Peter Lundberg, Patrik Nasr, Mattias Ekstedt, Karin Rådholm (2025) Microvascular complications of type 2 diabetes with or without MASLD: the EPSOMIP study, a primary care cohort study BMC Primary Care, Vol. 26, Article 354 (Article in journal) Continue to DOI

News

Mattias Ekstedt, Nils Dahlström, Peter Lundberg, Bengt Norén and Patrik Nasr.

Liver examinations without needles

How is your liver doing? Decades of research into the use of magnet resonance imaging is now being put to work to gain information about patients’ livers – without needles.

European project to develop better tests for liver disease

A large European research project aims to develop better diagnostics to predict which patients with non-alcoholic fatty liver disease run the highest risk of developing severe disease.
Microscopy image of fat in the liver.

Magnetic resonance finds fatty liver

Taking tissue samples to diagnose fatty liver can be replaced in most cases by a painless magnetic resonance investigation, according to a new study.

Research group

Bild på utsnitt av fettlever

Metabolic dysfunction-associated steatotic liver disease (MASLD)

Metabolic dysfunction-associated steatotic liver disease (MASLD) previously known as non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease which has become the most common liver disease affecting adults and children.

Publications

Selected publications

image from publication
Patrik Nasr, Mikael F. Forsgren, Simone Ignatova, Nils Dahlström, Gunnar Cedersund, Olof Dahlqvist Leinhard, Bengt Norén, Mattias Ekstedt, Peter Lundberg, Stergios Kechagias (2017)
Using a 3% Proton Density Fat Fraction as a Cut-off Value Increases Sensitivity of Detection of Hepatic Steatosis, Based on Results from Histopathology Analysis

Gastroenterology , Vol.153 , s.53-+ Continue to DOI

Mattias Ekstedt, Hannes Hagström, Patrik Nasr, Mats Fredrikson, Per Stål, Stergios Kechagias, Rolf Hultcrantz (2015)
Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up

Hepatology , Vol.61 , s.1547-1554 Continue to DOI

Stergios Kechagias, Åsa Ernersson, Olof Dahlqvist Leinhard, Peter Lundberg, Torbjörn Lindström, Fredrik Nyström, Toste Länne (2008)
Fast-food-based hyper-alimentation can induce rapid and profound elevation of serum alanine aminotransferase in healthy subjects

Gut , Vol.57 , s.649-654 Continue to DOI

Recent publications

2026

Magnus Holmer, Michael Ingre, Martti Farkkila, Cyriel Ponsioen, Bregje Mol, Christoph Schramm, Trine Folseraas, Kristine Wiencke, Nora Cazzagon, Elisa Catanzaro, Antonio Molinaro, Emma Nilsson, Johan Vessby, Stergios Kechagias, Nils Nyhlin, Marten Werner, Annika Bergquist (2026) Cirrhosis and age are key determinants of HCC risk in individuals with primary sclerosing cholangitis: A multicenter longitudinal cohort study Hepatology, Vol. 83 (Article in journal) Continue to DOI
Ángel Herraiz-Adillo, Karin Rådholm, Fredrik Iredahl, Carljohan Carlhäll, Nahuel Roemkens, Mikael Forsgren, Olof Dahlqvist Leinhard, Peter Lundberg, Stergios Kechagias, Nils Dahlström, Patrik Nasr, Mattias Ekstedt, Pontus Henriksson (2026) Validity of the International Fitness Scale (IFIS) and its associations with cardiometabolic health and body composition in adults with type 2 diabetes: A cross-sectional study PLOS ONE, Vol. 21, Article e0339364 (Article in journal) Continue to DOI

2025

Magnus Holmer, Michael Ingre, Martti Farkkila, Cyriel Ponsioen, Bregje Mol, Christoph Schramm, Trine Folseraas, Kristine Wiencke, Nora Cazzagon, Elisa Catanzaro, Antonio Molinaro, Emma Nilsson, Johan Vessby, Stergios Kechagias, Nils Nyhlin, Marten Werner, Annika Bergquist (2025) Reply: Competing risk and surveillance thresholds for HCC in patients with PSC Hepatology, Article PMID 8302946 (Article in journal) Continue to DOI
Grazia Pennisi, Gabriele Di Maria, Vincent Wai-Sun Wong, Victor de Ledinghen, Giada Sebastiani, Mauro Vigano, Anna Ludovica Fracanzani, Luca Miele, Elisabetta Bugianesi, Mattias Ekstedt, Roberta D'Ambrosio, Federico Ravaioli, Filippo Schepis, Fabio Marra, Alessio Aghemo, Gianluca Svegliati-Baroni, Marcello Persico, Luca Valenti, Annalisa Berzigotti, Jacob George, Angelo Armandi, Patrik Nasr, Stergios Kechagias, Antonio Liguori, Dario Saltini, Yuly P. Mendoza, Vincenza Calvaruso, Marco Enea, Huapeng Lin, Giuseppe Infantino, Mario Masarone, Nicola Pugliese, Adele Tulone, Vito Di Marco, Calogero Camma, Salvatore Petta (2025) Impact of first and further decompensation in patients with compensated ACLD due to MASLD Journal of Hepatology, Vol. 83, p. 1266-1277 (Article in journal) Continue to DOI
Martin Bergram, Stergios Kechagias, Fredrik Iredahl, Wile Balkhed, Markus Holmberg, Nils Dahlström, Peter Lundberg, Patrik Nasr, Mattias Ekstedt, Karin Rådholm (2025) Microvascular complications of type 2 diabetes with or without MASLD: the EPSOMIP study, a primary care cohort study BMC Primary Care, Vol. 26, Article 354 (Article in journal) Continue to DOI

About me

CV

  • Reg. Physician 1996
  • PhD 2001
  • Professor 2013

Teaching

  • The Medical Program

Awards

  • Pedagogue of the Year, 2017
  • Bergdahl Award, 2022

Organisation

Close up of three doctors dressed in surgical clothes. One stands with his back to the camera.

Division of Diagnostics and Specialist Medicine (DISP)

The division consists of three units (internal medicine, cardiovascular and radiological sciences) and contains seven subject areas within which research and teaching are conducted.
Illustration of the letters HMV

Department of Health, Medicine and Caring Sciences (HMV)

The research areas at HMV include experimental basic research to clinical, social and public health research. We conduct high-quality education in the sought-after care professions.
Five people in a laboratory.

Faculty of Medicine and Health Sciences (MEDFAK)

The Faculty of Medicine and Health Sciences conducts research and education within medicine, healthcare and public health.

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