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Stergios Kechagias

Professor

Professor in internal medicine

Research on metabolic dysfunction-associated steatotic liver disease (MASLD)

MASLD has become the most common liver disease affecting adults and children.

Our research purposes are to further characterize the natural history of MASLD, identify factors that influence the progression of MASLD, and to develop and validate diagnostic methods for MASLD.

Publications

2026

Wolf Bartholomä, Shan Cai, Christian Simonsson, Markus Karlsson, Stergios Kechagias, Mischa Woisetschläger, Nils Dahlström, Peter Lundberg (2026) Pharmacokinetic modelling of MRI-based liver function for risk assessment in primary sclerosing cholangitis: a prospective pilot study European Radiology Experimental, Vol. 10, Article 91 (Article in journal) https://dx.doi.org/10.1186/s41747-026-00764-5
Sara F. Hansson, Patrik Nasr, Jane Knochel, Tasso Miliotis, Anne-Christine Andreasson, Andreas Hober, Ann-Christin Nystrom, Linnea Bergenholm, Mahssa Karimi, Xiao-Rong Peng, Mattias Ekstedt, Stergios Kechagias, Mathias Liljeblad (2026) Fibroblast activation protein and down-stream effects on its substrates in metabolic dysfunction-associated steatotic liver disease Scandinavian Journal of Gastroenterology (Article in journal) https://dx.doi.org/10.1080/00365521.2026.2679101
Signe Swerkersson, Wolf Bartholomä, Mikael Forsgren, Henrik Stjernman, Daniel Sjögren, Stergios Kechagias, Patrik Nasr, Markus Holmberg, Peter Lundberg, Martin Rejler, Olof Dahlqvist Leinhard, Nils Dahlström, Mattias Ekstedt (2026) Clinical relevance and reproducibility of morphological MRI findings in liver cirrhosis: Results from ACCESS-ESLD European Journal of Radiology, Vol. 200, Article 112845 (Article in journal) https://dx.doi.org/10.1016/j.ejrad.2026.112845
Shan Cai, Christian Simonsson, Markus Karlsson, Wile Balkhed, Jens Tellman, Simone Ignatova, Patrik Nasr, Mattias Ekstedt, Stergios Kechagias, Wolf Bartholomä, Nils Dahlström, Peter Lundberg (2026) Chronic Liver Disease: Assessing Inflammation and Fibrosis Using Three‐Dimensional MR Elastography With Same‐Day Biopsy in a Prospective Cohort Journal of Magnetic Resonance Imaging, Vol. 64, p. 306-319, Article jmri.70319 (Article in journal) https://dx.doi.org/10.1002/jmri.70319
Xiao-Dong Zhou, Yu-Ting Li, Seung Up Kim, Terry Cheuk-Fung Yip, Salvatore Petta, Atsushi Nakajima, Emmanuel Tsochatzis, Junping Shi, Wah-Kheong Chan, Jerome Boursier, Elisabetta Bugianesi, Yusuf Yilmaz, Hannes Hagstrom, Manuel Romero-Gomez, Khalid Alswat, Jose Luis Calleja, Hirokazu Takahashi, Victor de Ledinghen, Shalimar, Laurent Castera, Arun J. Sanyal, George Boon-Bee Goh, Philip N. Newsome, Jian-Gao Fan, Michelle Lai, Sandeep Aggarwal, Stergios Kechagias, Yoichi Hiasa, Zhongtao Zhang, Jacob George, Mohamed El-Kassas, Jinjun Chen, Hong You, Barham K. Abu Dayyeh, Huiping Sheng, Leon A. Adams, Jing Wang, Fangping He, Huiqing Liang, Yong-Feng Yang, Xiaoling Chi, Bihui Zhong, Yan Bi, Yuqiang Mi, Yongfen Zhu, Rixing Bai, Jing Zhang, Bingyuan Wang, Jinghai Song, Hong Deng, Qing Xie, Lang Bai, Yongning Xin, Wen Xie, Jie Li, Celine Fournier-Poizat, Chutian Wu, Hye Won Lee, Grace Lai-Hung Wong, Angelo Armandi, Ying Shang, Grazia Pennisi, Elba Llop, Masato Yoneda, Marc de Saint-Loup, Carmen Lara-Romero, Rocio Gallego-Duran, Amon Asgharpour, Kevin Kim-Jun Teh, Mandy Sau-Wai Chan, Huapeng Lin, Wen-Yue Liu, Sherlot Juan Song, Waleed K. Al-Hamoudi, Hiroshi Isoda, Teruki Miyake, Sanjaya K. Satapathy, Mengyi Li, Keshni Sharma, Mohammed Emadeldeen, Ling Zhou, Xiaofei Tong, Fateh Bazerbachi, Xiaotang Fan, Huanming Xiao, Junzhao Ye, Liang Xu, Xiaolin Wang, Yi-Xuan Wei, Mirko Zoncape, Wenhao Li, Vincent Wai-Sun Wong, Ming-Hua Zheng (2026) Longitudinal Changes in Fibrosis Markers: Monitoring Stiffness/Fibrosis Progression and Prognostic Outcomes in MASLD Clinical Gastroenterology and Hepatology, Vol. 24, p. 394-406 (Article in journal) https://dx.doi.org/10.1016/j.cgh.2025.07.011

News

Mattias Ekstedt, Nils Dahlström, Peter Lundberg, Bengt Norén and Patrik Nasr.

Liver examinations without needles

How is your liver doing? Decades of research into the use of magnet resonance imaging is now being put to work to gain information about patients’ livers – without needles.

European project to develop better tests for liver disease

A large European research project aims to develop better diagnostics to predict which patients with non-alcoholic fatty liver disease run the highest risk of developing severe disease.
Microscopy image of fat in the liver.

Magnetic resonance finds fatty liver

Taking tissue samples to diagnose fatty liver can be replaced in most cases by a painless magnetic resonance investigation, according to a new study.

Research group

Bild på utsnitt av fettlever

Metabolic dysfunction-associated steatotic liver disease (MASLD)

Metabolic dysfunction-associated steatotic liver disease (MASLD) previously known as non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease which has become the most common liver disease affecting adults and children.

Publications

Selected publications

image from publication
Patrik Nasr, Mikael F. Forsgren, Simone Ignatova, Nils Dahlström, Gunnar Cedersund, Olof Dahlqvist Leinhard, Bengt Norén, Mattias Ekstedt, Peter Lundberg, Stergios Kechagias (2017)
Using a 3% Proton Density Fat Fraction as a Cut-off Value Increases Sensitivity of Detection of Hepatic Steatosis, Based on Results from Histopathology Analysis

Gastroenterology , Vol.153 , s.53-+ Continue to DOI

Mattias Ekstedt, Hannes Hagström, Patrik Nasr, Mats Fredrikson, Per Stål, Stergios Kechagias, Rolf Hultcrantz (2015)
Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up

Hepatology , Vol.61 , s.1547-1554 Continue to DOI

Stergios Kechagias, Åsa Ernersson, Olof Dahlqvist Leinhard, Peter Lundberg, Torbjörn Lindström, Fredrik Nyström, Toste Länne (2008)
Fast-food-based hyper-alimentation can induce rapid and profound elevation of serum alanine aminotransferase in healthy subjects

Gut , Vol.57 , s.649-654 Continue to DOI

Recent publications

2026

Wolf Bartholomä, Shan Cai, Christian Simonsson, Markus Karlsson, Stergios Kechagias, Mischa Woisetschläger, Nils Dahlström, Peter Lundberg (2026) Pharmacokinetic modelling of MRI-based liver function for risk assessment in primary sclerosing cholangitis: a prospective pilot study European Radiology Experimental, Vol. 10, Article 91 (Article in journal) https://dx.doi.org/10.1186/s41747-026-00764-5
Sara F. Hansson, Patrik Nasr, Jane Knochel, Tasso Miliotis, Anne-Christine Andreasson, Andreas Hober, Ann-Christin Nystrom, Linnea Bergenholm, Mahssa Karimi, Xiao-Rong Peng, Mattias Ekstedt, Stergios Kechagias, Mathias Liljeblad (2026) Fibroblast activation protein and down-stream effects on its substrates in metabolic dysfunction-associated steatotic liver disease Scandinavian Journal of Gastroenterology (Article in journal) https://dx.doi.org/10.1080/00365521.2026.2679101
Signe Swerkersson, Wolf Bartholomä, Mikael Forsgren, Henrik Stjernman, Daniel Sjögren, Stergios Kechagias, Patrik Nasr, Markus Holmberg, Peter Lundberg, Martin Rejler, Olof Dahlqvist Leinhard, Nils Dahlström, Mattias Ekstedt (2026) Clinical relevance and reproducibility of morphological MRI findings in liver cirrhosis: Results from ACCESS-ESLD European Journal of Radiology, Vol. 200, Article 112845 (Article in journal) https://dx.doi.org/10.1016/j.ejrad.2026.112845
Shan Cai, Christian Simonsson, Markus Karlsson, Wile Balkhed, Jens Tellman, Simone Ignatova, Patrik Nasr, Mattias Ekstedt, Stergios Kechagias, Wolf Bartholomä, Nils Dahlström, Peter Lundberg (2026) Chronic Liver Disease: Assessing Inflammation and Fibrosis Using Three‐Dimensional MR Elastography With Same‐Day Biopsy in a Prospective Cohort Journal of Magnetic Resonance Imaging, Vol. 64, p. 306-319, Article jmri.70319 (Article in journal) https://dx.doi.org/10.1002/jmri.70319
Xiao-Dong Zhou, Yu-Ting Li, Seung Up Kim, Terry Cheuk-Fung Yip, Salvatore Petta, Atsushi Nakajima, Emmanuel Tsochatzis, Junping Shi, Wah-Kheong Chan, Jerome Boursier, Elisabetta Bugianesi, Yusuf Yilmaz, Hannes Hagstrom, Manuel Romero-Gomez, Khalid Alswat, Jose Luis Calleja, Hirokazu Takahashi, Victor de Ledinghen, Shalimar, Laurent Castera, Arun J. Sanyal, George Boon-Bee Goh, Philip N. Newsome, Jian-Gao Fan, Michelle Lai, Sandeep Aggarwal, Stergios Kechagias, Yoichi Hiasa, Zhongtao Zhang, Jacob George, Mohamed El-Kassas, Jinjun Chen, Hong You, Barham K. Abu Dayyeh, Huiping Sheng, Leon A. Adams, Jing Wang, Fangping He, Huiqing Liang, Yong-Feng Yang, Xiaoling Chi, Bihui Zhong, Yan Bi, Yuqiang Mi, Yongfen Zhu, Rixing Bai, Jing Zhang, Bingyuan Wang, Jinghai Song, Hong Deng, Qing Xie, Lang Bai, Yongning Xin, Wen Xie, Jie Li, Celine Fournier-Poizat, Chutian Wu, Hye Won Lee, Grace Lai-Hung Wong, Angelo Armandi, Ying Shang, Grazia Pennisi, Elba Llop, Masato Yoneda, Marc de Saint-Loup, Carmen Lara-Romero, Rocio Gallego-Duran, Amon Asgharpour, Kevin Kim-Jun Teh, Mandy Sau-Wai Chan, Huapeng Lin, Wen-Yue Liu, Sherlot Juan Song, Waleed K. Al-Hamoudi, Hiroshi Isoda, Teruki Miyake, Sanjaya K. Satapathy, Mengyi Li, Keshni Sharma, Mohammed Emadeldeen, Ling Zhou, Xiaofei Tong, Fateh Bazerbachi, Xiaotang Fan, Huanming Xiao, Junzhao Ye, Liang Xu, Xiaolin Wang, Yi-Xuan Wei, Mirko Zoncape, Wenhao Li, Vincent Wai-Sun Wong, Ming-Hua Zheng (2026) Longitudinal Changes in Fibrosis Markers: Monitoring Stiffness/Fibrosis Progression and Prognostic Outcomes in MASLD Clinical Gastroenterology and Hepatology, Vol. 24, p. 394-406 (Article in journal) https://dx.doi.org/10.1016/j.cgh.2025.07.011

About me

CV

  • Reg. Physician 1996
  • PhD 2001
  • Professor 2013

Teaching

  • The Medical Program

Awards

  • Pedagogue of the Year, 2017
  • Bergdahl Award, 2022

Organisation

Close up of three doctors dressed in surgical clothes. One stands with his back to the camera.

Division of Diagnostics and Specialist Medicine (DISP)

The division consists of three units (internal medicine, cardiovascular and radiological sciences) and contains seven subject areas within which research and teaching are conducted.
Illustration of the letters HMV

Department of Health, Medicine and Caring Sciences (HMV)

The research areas at HMV include experimental basic research to clinical, social and public health research. We conduct high-quality education in the sought-after care professions.
Five people in a laboratory.

Faculty of Medicine and Health Sciences (MEDFAK)

The Faculty of Medicine and Health Sciences conducts research and education within medicine, healthcare and public health.