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Stergios Kechagias

Professor

Professor in internal medicine

Research on metabolic dysfunction-associated steatotic liver disease (MASLD)

MASLD has become the most common liver disease affecting adults and children.

Our research purposes are to further characterize the natural history of MASLD, identify factors that influence the progression of MASLD, and to develop and validate diagnostic methods for MASLD.

Publications

2024

Annika Bergquist, Mattias Ekstedt, Hannes Hagstrom, Gunnar Jarnerot, Stefan Lindgren, Emma Nilsson, Nils Nyhlin, Fredrik Rorsman, Per Stal, Marten Werner, Stergios Swehep, Stergios Kechagias (2024) Forty years of successful national research collaboration in liver disease - the Swedish experience Scandinavian Journal of Gastroenterology (Article, review/survey) Continue to DOI
Michele Vacca, Ioannis Kamzolas, Lea Morch Harder, Fiona Oakley, Christian Trautwein, Maximilian Hatting, Trenton Ross, Barbara Bernardo, Anouk Oldenburger, Sara Toftegaard Hjuler, Iwona Ksiazek, Daniel Linden, Detlef Schuppan, Sergio Rodriguez-Cuenca, Maria Manuela Tonini, Tamara R. Castaneda, Aimo Kannt, Cecilia M. P. Rodrigues, Simon Cockell, Olivier Govaere, Ann K. Daly, Michael Allison, Kristian Honnens de Lichtenberg, Yong Ook Kim, Anna Lindblom, Stephanie Oldham, Anne-Christine Andreasson, Franklin Schlerman, Jonathon Marioneaux, Arun Sanyal, Marta B. Afonso, Ramy Younes, Yuichiro Amano, Scott L. Friedman, Shuang Wang, Dipankar Bhattacharya, Eric Simon, Valerie Paradis, Alastair Burt, Ioanna Maria Grypari, Susan Davies, Ann Driessen, Hiroaki Yashiro, Susanne Pors, Maja Worm Andersen, Michael Feigh, Carla Yunis, Pierre Bedossa, Michelle Stewart, Heather L. Cater, Sara Wells, Joern M. Schattenberg, Quentin M. Anstee, Dina Tiniakos, James W. Perfield, Evangelia Petsalaki, Peter Davidsen, Antonio Vidal-Puig, Quentin M. Anstee, Ann K. Daly, Simon Cockell, Dina Tiniakos, Pierre Bedossa, Alastair Burt, Fiona Oakley, Heather J. Cordell, Christopher P. Day, Kristy Wonders, Paolo Missier, Matthew McTeer, Luke Vale, Yemi Oluboyede, Matt Breckons, Jo Boyle, Patrick M. Bossuyt, Hadi Zafarmand, Yasaman Vali, Jenny Lee, Max Nieuwdorp, Adriaan G. Holleboom, Athanasios Angelakis, Joanne Verheij, Vlad Ratziu, Karine Clement, Rafael Patino-Navarrete, Raluca Pais, Valerie Paradis, Detlef Schuppan, Joern M. Schattenberg, Rambabu Surabattula, Sudha Myneni, Yong Ook Kim, Beate K. Straub, Antonio Vidal-Puig, Michele Vacca, Sergio Rodrigues-Cuenca, Mike Allison, Ioannis Kamzolas, Evangelia Petsalaki, Mark Campbell, Chris J. Lelliott, Susan Davies, Matej Oresic, Tuulia Hyotylainen, Aidan McGlinchey, Jose M. Mato, Oscar Millet, Jean-Francois Dufour, Annalisa Berzigotti, Mojgan Masoodi, Naomi F. Lange, Michael Pavlides, Stephen Harrison, Stefan Neubauer, Jeremy Cobbold, Ferenc Mozes, Salma Akhtar, Seliat Olodo-Atitebi, Rajarshi Banerjee, Elizabeth Shumbayawonda, Andrea Dennis, Anneli Andersson, Ioan Wigley, Manuel Romero-Gomez, Emilio Gomez-Gonzalez, Javier Ampuero, Javier Castell, Rocio Gallego-Duran, Isabel Fernandez-Lizaranzu, Rocio Montero-Vallejo, Morten Karsdal, Daniel Guldager Kring Rasmussen, Diana Julie Leeming, Antonia Sinisi, Kishwar Musa, Estelle Sandt, Maria Manuela Tonini, Elisabetta Bugianesi, Chiara Rosso, Angelo Armandi, Fabio Marra, Amalia Gastaldelli, Gianluca Svegliati, Jerome Boursier, Sven Francque, Luisa Vonghia, An Verrijken, Eveline Dirinck, Ann Driessen, Mattias Ekstedt, Stergios Kechagias, Hannele Yki-Jarvinen, Kimmo Porthan, Johanna Arola, Saskia van Mil, George Papatheodoridis, Helena Cortez-Pinto, Ana Paula Silva, Cecilia M. P. Rodrigues, Luca Valenti, Serena Pelusi, Salvatore Petta, Grazia Pennisi, Luca Miele, Antonio Liguori, Andreas Geier, Monika Rau, Christian Trautwein, Johanna Reissing, Guruprasad P. Aithal, Susan Francis, Naaventhan Palaniyappan, Christopher Bradley, Paul Hockings, Moritz Schneider, Philip N. Newsome, Stefan Hubscher, David Wenn, Jeremy Magnanensi, Aldo Trylesinski, Rebeca Mayo, Cristina Alonso, Kevin Duffin, James W. Perfield, Yu Chen, Mark L. Hartman, Carla Yunis, Melissa Miller, Yan Chen, Euan James McLeod, Trenton Ross, Barbara Bernardo, Corinna Schoelch, Judith Ertle, Ramy Younes, Harvey Coxson, Eric Simon, Joseph Gogain, Rachel Ostroff, Leigh Alexander, Hannah Biegel, Mette Skalshoi Kjaer, Lea Morch Harder, Naba Al-Sari, Sanne Skovgard Veidal, Anouk Oldenburger, Jens Ellegaard, Maria-Magdalena Balp, Lori Jennings, Miljen Martic, Jurgen Loffler, Douglas Applegate, Richard Torstenson, Daniel Linden, Celine Fournier-Poizat, Anne Llorca, Michael Kalutkiewicz, Kay Pepin, Richard Ehman, Gerald Horan, Gideon Ho, Dean Tai, Elaine Chng, Teng Xiao, Scott D. Patterson, Andrew Billin, Lynda Doward, James Twiss, Paresh Thakker, Zoltan Derdak, Hiroaki Yashiro, Henrik Landgren, Carolin Lackner, Annette Gouw, Prodromos Hytiroglou, Olivier Govaere, Clifford Brass (2024) An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD) Nature Metabolism, Vol. 6, p. 1178-+ (Article in journal) Continue to DOI
Ying Shang, Camilla Akbari, Maja Dodd, Xiao Zhang, Tongtong Wang, Thomas Jemielita, Gail Fernandes, Samuel S. Engel, Patrik Nasr, Johan Vessby, Fredrik Rorsman, Stergios Kechagias, Per Stal, Mattias Ekstedt, Hannes Hagstrom (2024) Association between longitudinal biomarkers and major adverse liver outcomes in patients with non-cirrhotic metabolic dysfunction-associated steatotic liver disease Hepatology (Article in journal) Continue to DOI
Hannes Hegmar, Thomas Wiggers, Patrik Nasr, Johan Vessby, Stergios Kechagias, Nils Nyhlin, Hanns-Ulrich Marschall, Asa Danielsson Borssen, Rickard Strandberg, Morten Karsdal, Diana Julie Leeming, Mattias Ekstedt, Hannes Hagstrom (2024) Performance of novel collagen turnover biomarkers to detect increased liver stiffness in MASLD Journal of Internal Medicine, Vol. 296, p. 177-186 (Article in journal) Continue to DOI
Patrik Nasr, Axel Wester, Mattias Ekstedt, Rickard Strandberg, Stergios Kechagias, Ying Shang, Linnea Widman, Hannes Hagstrom (2024) Misclassified Alcohol-related Liver Disease is Common in Presumed Metabolic Dysfunction-associated Steatotic Liver Disease and Highly Increases Risk for Future Cirrhosis Clinical Gastroenterology and Hepatology, Vol. 22 (Article in journal) Continue to DOI

News

Mattias Ekstedt, Nils Dahlström, Peter Lundberg, Bengt Norén and Patrik Nasr.

Liver examinations without needles

How is your liver doing? Decades of research into the use of magnet resonance imaging is now being put to work to gain information about patients’ livers – without needles.

European project to develop better tests for liver disease

A large European research project aims to develop better diagnostics to predict which patients with non-alcoholic fatty liver disease run the highest risk of developing severe disease.
Microscopy image of fat in the liver.

Magnetic resonance finds fatty liver

Taking tissue samples to diagnose fatty liver can be replaced in most cases by a painless magnetic resonance investigation, according to a new study.

Research group

Microscopy image of liver. White areas represent accumulated fat.

Metabolic dysfunction-associated steatotic liver disease (MASLD)

Metabolic dysfunction-associated steatotic liver disease (MASLD) previously known as non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease which has become the most common liver disease affecting adults and children.

Publications

Selected publications

Cover of publication 'image from publication'
Patrik Nasr, Mikael F. Forsgren, Simone Ignatova, Nils Dahlström, Gunnar Cedersund, Olof Dahlqvist Leinhard, Bengt Norén, Mattias Ekstedt, Peter Lundberg, Stergios Kechagias (2017)
Using a 3% Proton Density Fat Fraction as a Cut-off Value Increases Sensitivity of Detection of Hepatic Steatosis, Based on Results from Histopathology Analysis

Gastroenterology , Vol.153 , s.53-+ Continue to DOI

Cover of publication ''
Mattias Ekstedt, Hannes Hagström, Patrik Nasr, Mats Fredrikson, Per Stål, Stergios Kechagias, Rolf Hultcrantz (2015)
Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up

Hepatology , Vol.61 , s.1547-1554 Continue to DOI

Cover of publication ''
Stergios Kechagias, Åsa Ernersson, Olof Dahlqvist Leinhard, Peter Lundberg, Torbjörn Lindström, Fredrik Nyström, Toste Länne (2008)
Fast-food-based hyper-alimentation can induce rapid and profound elevation of serum alanine aminotransferase in healthy subjects

Gut , Vol.57 , s.649-654 Continue to DOI

Recent publications

2024

Annika Bergquist, Mattias Ekstedt, Hannes Hagstrom, Gunnar Jarnerot, Stefan Lindgren, Emma Nilsson, Nils Nyhlin, Fredrik Rorsman, Per Stal, Marten Werner, Stergios Swehep, Stergios Kechagias (2024) Forty years of successful national research collaboration in liver disease - the Swedish experience Scandinavian Journal of Gastroenterology (Article, review/survey) Continue to DOI
Michele Vacca, Ioannis Kamzolas, Lea Morch Harder, Fiona Oakley, Christian Trautwein, Maximilian Hatting, Trenton Ross, Barbara Bernardo, Anouk Oldenburger, Sara Toftegaard Hjuler, Iwona Ksiazek, Daniel Linden, Detlef Schuppan, Sergio Rodriguez-Cuenca, Maria Manuela Tonini, Tamara R. Castaneda, Aimo Kannt, Cecilia M. P. Rodrigues, Simon Cockell, Olivier Govaere, Ann K. Daly, Michael Allison, Kristian Honnens de Lichtenberg, Yong Ook Kim, Anna Lindblom, Stephanie Oldham, Anne-Christine Andreasson, Franklin Schlerman, Jonathon Marioneaux, Arun Sanyal, Marta B. Afonso, Ramy Younes, Yuichiro Amano, Scott L. Friedman, Shuang Wang, Dipankar Bhattacharya, Eric Simon, Valerie Paradis, Alastair Burt, Ioanna Maria Grypari, Susan Davies, Ann Driessen, Hiroaki Yashiro, Susanne Pors, Maja Worm Andersen, Michael Feigh, Carla Yunis, Pierre Bedossa, Michelle Stewart, Heather L. Cater, Sara Wells, Joern M. Schattenberg, Quentin M. Anstee, Dina Tiniakos, James W. Perfield, Evangelia Petsalaki, Peter Davidsen, Antonio Vidal-Puig, Quentin M. Anstee, Ann K. Daly, Simon Cockell, Dina Tiniakos, Pierre Bedossa, Alastair Burt, Fiona Oakley, Heather J. Cordell, Christopher P. Day, Kristy Wonders, Paolo Missier, Matthew McTeer, Luke Vale, Yemi Oluboyede, Matt Breckons, Jo Boyle, Patrick M. Bossuyt, Hadi Zafarmand, Yasaman Vali, Jenny Lee, Max Nieuwdorp, Adriaan G. Holleboom, Athanasios Angelakis, Joanne Verheij, Vlad Ratziu, Karine Clement, Rafael Patino-Navarrete, Raluca Pais, Valerie Paradis, Detlef Schuppan, Joern M. Schattenberg, Rambabu Surabattula, Sudha Myneni, Yong Ook Kim, Beate K. Straub, Antonio Vidal-Puig, Michele Vacca, Sergio Rodrigues-Cuenca, Mike Allison, Ioannis Kamzolas, Evangelia Petsalaki, Mark Campbell, Chris J. Lelliott, Susan Davies, Matej Oresic, Tuulia Hyotylainen, Aidan McGlinchey, Jose M. Mato, Oscar Millet, Jean-Francois Dufour, Annalisa Berzigotti, Mojgan Masoodi, Naomi F. Lange, Michael Pavlides, Stephen Harrison, Stefan Neubauer, Jeremy Cobbold, Ferenc Mozes, Salma Akhtar, Seliat Olodo-Atitebi, Rajarshi Banerjee, Elizabeth Shumbayawonda, Andrea Dennis, Anneli Andersson, Ioan Wigley, Manuel Romero-Gomez, Emilio Gomez-Gonzalez, Javier Ampuero, Javier Castell, Rocio Gallego-Duran, Isabel Fernandez-Lizaranzu, Rocio Montero-Vallejo, Morten Karsdal, Daniel Guldager Kring Rasmussen, Diana Julie Leeming, Antonia Sinisi, Kishwar Musa, Estelle Sandt, Maria Manuela Tonini, Elisabetta Bugianesi, Chiara Rosso, Angelo Armandi, Fabio Marra, Amalia Gastaldelli, Gianluca Svegliati, Jerome Boursier, Sven Francque, Luisa Vonghia, An Verrijken, Eveline Dirinck, Ann Driessen, Mattias Ekstedt, Stergios Kechagias, Hannele Yki-Jarvinen, Kimmo Porthan, Johanna Arola, Saskia van Mil, George Papatheodoridis, Helena Cortez-Pinto, Ana Paula Silva, Cecilia M. P. Rodrigues, Luca Valenti, Serena Pelusi, Salvatore Petta, Grazia Pennisi, Luca Miele, Antonio Liguori, Andreas Geier, Monika Rau, Christian Trautwein, Johanna Reissing, Guruprasad P. Aithal, Susan Francis, Naaventhan Palaniyappan, Christopher Bradley, Paul Hockings, Moritz Schneider, Philip N. Newsome, Stefan Hubscher, David Wenn, Jeremy Magnanensi, Aldo Trylesinski, Rebeca Mayo, Cristina Alonso, Kevin Duffin, James W. Perfield, Yu Chen, Mark L. Hartman, Carla Yunis, Melissa Miller, Yan Chen, Euan James McLeod, Trenton Ross, Barbara Bernardo, Corinna Schoelch, Judith Ertle, Ramy Younes, Harvey Coxson, Eric Simon, Joseph Gogain, Rachel Ostroff, Leigh Alexander, Hannah Biegel, Mette Skalshoi Kjaer, Lea Morch Harder, Naba Al-Sari, Sanne Skovgard Veidal, Anouk Oldenburger, Jens Ellegaard, Maria-Magdalena Balp, Lori Jennings, Miljen Martic, Jurgen Loffler, Douglas Applegate, Richard Torstenson, Daniel Linden, Celine Fournier-Poizat, Anne Llorca, Michael Kalutkiewicz, Kay Pepin, Richard Ehman, Gerald Horan, Gideon Ho, Dean Tai, Elaine Chng, Teng Xiao, Scott D. Patterson, Andrew Billin, Lynda Doward, James Twiss, Paresh Thakker, Zoltan Derdak, Hiroaki Yashiro, Henrik Landgren, Carolin Lackner, Annette Gouw, Prodromos Hytiroglou, Olivier Govaere, Clifford Brass (2024) An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD) Nature Metabolism, Vol. 6, p. 1178-+ (Article in journal) Continue to DOI
Ying Shang, Camilla Akbari, Maja Dodd, Xiao Zhang, Tongtong Wang, Thomas Jemielita, Gail Fernandes, Samuel S. Engel, Patrik Nasr, Johan Vessby, Fredrik Rorsman, Stergios Kechagias, Per Stal, Mattias Ekstedt, Hannes Hagstrom (2024) Association between longitudinal biomarkers and major adverse liver outcomes in patients with non-cirrhotic metabolic dysfunction-associated steatotic liver disease Hepatology (Article in journal) Continue to DOI
Hannes Hegmar, Thomas Wiggers, Patrik Nasr, Johan Vessby, Stergios Kechagias, Nils Nyhlin, Hanns-Ulrich Marschall, Asa Danielsson Borssen, Rickard Strandberg, Morten Karsdal, Diana Julie Leeming, Mattias Ekstedt, Hannes Hagstrom (2024) Performance of novel collagen turnover biomarkers to detect increased liver stiffness in MASLD Journal of Internal Medicine, Vol. 296, p. 177-186 (Article in journal) Continue to DOI
Patrik Nasr, Axel Wester, Mattias Ekstedt, Rickard Strandberg, Stergios Kechagias, Ying Shang, Linnea Widman, Hannes Hagstrom (2024) Misclassified Alcohol-related Liver Disease is Common in Presumed Metabolic Dysfunction-associated Steatotic Liver Disease and Highly Increases Risk for Future Cirrhosis Clinical Gastroenterology and Hepatology, Vol. 22 (Article in journal) Continue to DOI

About me

CV

  • Reg. Physician 1996
  • PhD 2001
  • Professor 2013

Teaching

  • The Medical Program

Awards

  • Pedagogue of the Year, 2017
  • Bergdahl Award, 2022

Organisation

Close up of three doctors dressed in surgical clothes. One stands with his back to the camera.

Division of Diagnostics and Specialist Medicine (DISP)

The division consists of three units (internal medicine, cardiovascular and radiological sciences) and contains seven subject areas within which research and teaching are conducted.
Wordcloud research subjects at HMV

Department of Health, Medicine and Caring Sciences (HMV)

The research areas at HMV include experimental basic research to clinical, social and public health research. We conduct high-quality education in the sought-after care professions.
Five people in a laboratory.

Faculty of Medicine and Health Sciences (MEDFAK)

The Faculty of Medicine and Health Sciences conducts research and education within medicine, healthcare and public health.

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