Wen Zhong
Associate Professor, Docent
My research mainly focuses on the integration of multi-omics, the interplay between genetics and phenotypes, and the development of data-driven strategies/tools for precision medicine.
Publications
2026
Estradiol-associated extracellular signaling in the human breast in vivo identifies mast cells as tumor-supportive stromal mediators
Oncoimmunology, Vol. 15, Article 2746847
(Article in journal)
https://dx.doi.org/10.1080/2162402X.2026.2746847
Tissue-stiffness-driven platelet activation emerges as a potential target for breast cancer prevention and treatment
Cell Communication and Signaling, Vol. 24, Article 429
(Article in journal)
https://dx.doi.org/10.1186/s12964-026-03138-x
Correction: Longitudinal analysis of genetic and environmental interplay in human metabolic profiles and the implication for metabolic health (vol 17, 68, 2025)
Genome Medicine, Vol. 18, Article 99
(Article in journal)
https://dx.doi.org/10.1186/s13073-026-01705-y
Genetic predisposition to coffee consumption and the association with the early risk of atherosclerosis
Scientific Reports, Vol. 16, Article 9652
(Article in journal)
https://dx.doi.org/10.1038/s41598-026-44122-2
Habitual coffee consumption poorly correlates with sleep quality and daytime sleepiness: A cross-sectional study
PLOS ONE, Vol. 21, Article e0344479
(Article in journal)
https://dx.doi.org/10.1371/journal.pone.0344479
Selected publications
See full list in Google Scholar: https://scholar.google.com/citations?user=c7w5Bh4AAAAJ&hl=en
- Zhong W, Barde S, Mitsios N, Adori C, Oksvold P, Feilitzen K.V, O’Leary L, Csiba L, Hortobágyi T, Szocsics P and Mechawar N, Maglóczky Z, Renner E, Palkovits M, Uhlen M, Mulder J, Hökfelt T. (2022). The neuropeptide landscape of human prefrontal cortex. Proceedings of the National Academy of Sciences, 119(33), p.e2123146119.
https://www.pnas.org/doi/abs/10.1073/pnas.2123146119 - Zhong W, Altay O, Arif M, Edfors F, Mardinoglu A, Uhlén M, Fagerberg L. (2021). Next generation plasma proteome profiling of COVID-19 patients with mild to moderate symptoms. EBioMedicine 74, 103723
https://www.sciencedirect.com/science/article/pii/S235239642100517X - Zhong W, Edfors F, Gummesson A, Bergstrom G, Fagerberg L, Uhlén M. (2021). Next generation plasma proteome profiling to monitor health and disease. Nature communications 12 (1), 1-12
https://www.nature.com/articles/s41467-021-22767-z - Karlsson MJ, Zhang C, Méar L, Zhong W, Digre A, Katona B, Sjöstedt E, Butler L, Odeberg J, Dusart P, Edfors F, Oksvold P, von Feilitzon K, Zwahlen M, Muhammad A, Altay O, Li X, Ozcan M, Mardonoglu A, Fagerberg L, Mulder J, Luo Y, Ponten F, Uhlen M, Lindskog C. (2021). A single–cell type transcriptomics map of human tissues. Science Advances, 7(31), p.eabh2169.
https://www.science.org/doi/10.1126/sciadv.abh2169 - Zhong W, Danielsson H, Tebani A, Karlsson MJ, Elfvin A., Hellgren, G., Brusselaers, N., Brodin, P., Hellström, A., Fagerberg, L., Uhlén, M., (2021). Dramatic changes in blood protein levels during the first week of life in extremely preterm infants. Pediatric research, 89(3), pp.604-612.
https://www.nature.com/articles/s41390-020-0912-8 - Zhong W, Gummesson A, Tebani A, Karlsson M J, Hong MG, Schwenk JM, Edfors F, Bergström G, Fagerberg L, Uhlén M. (2020). Whole-genome sequence association analysis of blood proteins in a longitudinal wellness cohort. Genome Medicine, 12(1), 1-16.
https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-020-00755-0 - Tebani A, Gummesson A, Zhong W, Koistinen IS, Lakshmikanth T, Olsson LM, Boulund F, Neiman M, Stenlund H, Hellström C, Karlsson MJ, Arif M, Dodig-Crnković T, Mardinoglu A, Lee S, Zhang C, Chen Y, Olin A, Mikes J, Danielsson H, von Feilitzen K, Jansson PA, Angerås O, Huss M, Kjellqvist S, Odeberg J, Edfors F, Tremaroli V, Forsström B, Schwenk JM, Nilsson P, Moritz T, Bäckhed F, Engstrand L, Brodin P, Bergström G, Uhlén M, Fagerberg L. (2020). Integration of molecular profiles in a longitudinal wellness profiling cohort. Nature communications, 11(1), 1-14.
https://www.nature.com/articles/s41467-020-18148-7 - Sjöstedt E, Zhong W, Fagerberg L, Karlsson M, Mitsios N, Adori C, Oksvold P, Edfors F, Limiszewska A, Hikmet F, Huang J, Du Y, Lin L, Dong Z, Yang L, Liu X, Jiang H, Xu X, Wang J, Yang H, Bolund L, Mardinoglu A, Zhang C, von Feilitzen K, Lindskog C, Pontén F, Luo Y, Hökfelt T, Uhlén M, Mulder J. (2020). An atlas of the protein-coding genes in the human, pig, and mouse brain. Science, 367 (6482)
https://www.science.org/doi/10.1126/science.aay5947 - Uhlén M, Karlsson MJ, Zhong W, Tebani A, Pou C, Mikes J, Lakshmikanth T, Forsström B, Edfors F, Odeberg J, Mardinoglu A, Zhang C, von Feilitzen K, Mulder J, Sjöstedt E, Hober A, Oksvold P, Zwahlen M, Ponten F, Lindskog C, Sivertsson Å, Fagerberg L, Brodin P. (2019). A genome-wide transcriptomic analysis of protein-coding genes in human blood cells. Science, 366 (6472)
https://www.science.org/doi/10.1126/science.aax9198 - Hou J#, Li Z#, Zhong W#, Hao Q, Lei L, Wang L, Zhao D, Xu P, Zhou Y, Wang Y, Xu T. (2017). Temporal transcriptomic and proteomic landscapes of deteriorating pancreatic islets in type 2 diabetic rats. Diabetes, 66(8), 2188-2200 (# equal contribution)
https://diabetes.diabetesjournals.org/content/66/8/2188