Wen Zhong
Assistant Professor, Docent
My research mainly focuses on the integration of multi-omics, the interplay between genetics and phenotypes, and the development of data-driven strategies/tools for precision medicine.
Publications
2026
Genetic predisposition to coffee consumption and the association with the early risk of atherosclerosis
Scientific Reports, Vol. 16, Article 9652
(Article in journal)
https://dx.doi.org/10.1038/s41598-026-44122-2
Habitual coffee consumption poorly correlates with sleep quality and daytime sleepiness: A cross-sectional study
PLOS ONE, Vol. 21, Article e0344479
(Article in journal)
https://dx.doi.org/10.1371/journal.pone.0344479
Proteomic Profile in Retinopathy of Prematurity: A Secondary Analysis of the Mega Donna Mega Randomized Clinical Trial
JAMA ophthalmology, Vol. 144, p. 174-184
(Article in journal)
https://dx.doi.org/10.1001/jamaophthalmol.2025.5594
2025
Cholecystokinin in the central and peripheral nervous system
Cholecystokinin: from Gallbladder to Cognition and Beyond, p. 101-160
(Chapter in book)
https://dx.doi.org/10.1016/B978-0-443-23720-1.00026-5
HUBMet: an integrative database and analytical platform for human blood metabolites and metabolite-protein associations
Genome Biology, Vol. 27, Article 7
(Article in journal)
https://dx.doi.org/10.1186/s13059-025-03922-x
Selected publications
See full list in Google Scholar: https://scholar.google.com/citations?user=c7w5Bh4AAAAJ&hl=en
- Zhong W, Barde S, Mitsios N, Adori C, Oksvold P, Feilitzen K.V, O’Leary L, Csiba L, Hortobágyi T, Szocsics P and Mechawar N, Maglóczky Z, Renner E, Palkovits M, Uhlen M, Mulder J, Hökfelt T. (2022). The neuropeptide landscape of human prefrontal cortex. Proceedings of the National Academy of Sciences, 119(33), p.e2123146119.
https://www.pnas.org/doi/abs/10.1073/pnas.2123146119 - Zhong W, Altay O, Arif M, Edfors F, Mardinoglu A, Uhlén M, Fagerberg L. (2021). Next generation plasma proteome profiling of COVID-19 patients with mild to moderate symptoms. EBioMedicine 74, 103723
https://www.sciencedirect.com/science/article/pii/S235239642100517X - Zhong W, Edfors F, Gummesson A, Bergstrom G, Fagerberg L, Uhlén M. (2021). Next generation plasma proteome profiling to monitor health and disease. Nature communications 12 (1), 1-12
https://www.nature.com/articles/s41467-021-22767-z - Karlsson MJ, Zhang C, Méar L, Zhong W, Digre A, Katona B, Sjöstedt E, Butler L, Odeberg J, Dusart P, Edfors F, Oksvold P, von Feilitzon K, Zwahlen M, Muhammad A, Altay O, Li X, Ozcan M, Mardonoglu A, Fagerberg L, Mulder J, Luo Y, Ponten F, Uhlen M, Lindskog C. (2021). A single–cell type transcriptomics map of human tissues. Science Advances, 7(31), p.eabh2169.
https://www.science.org/doi/10.1126/sciadv.abh2169 - Zhong W, Danielsson H, Tebani A, Karlsson MJ, Elfvin A., Hellgren, G., Brusselaers, N., Brodin, P., Hellström, A., Fagerberg, L., Uhlén, M., (2021). Dramatic changes in blood protein levels during the first week of life in extremely preterm infants. Pediatric research, 89(3), pp.604-612.
https://www.nature.com/articles/s41390-020-0912-8 - Zhong W, Gummesson A, Tebani A, Karlsson M J, Hong MG, Schwenk JM, Edfors F, Bergström G, Fagerberg L, Uhlén M. (2020). Whole-genome sequence association analysis of blood proteins in a longitudinal wellness cohort. Genome Medicine, 12(1), 1-16.
https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-020-00755-0 - Tebani A, Gummesson A, Zhong W, Koistinen IS, Lakshmikanth T, Olsson LM, Boulund F, Neiman M, Stenlund H, Hellström C, Karlsson MJ, Arif M, Dodig-Crnković T, Mardinoglu A, Lee S, Zhang C, Chen Y, Olin A, Mikes J, Danielsson H, von Feilitzen K, Jansson PA, Angerås O, Huss M, Kjellqvist S, Odeberg J, Edfors F, Tremaroli V, Forsström B, Schwenk JM, Nilsson P, Moritz T, Bäckhed F, Engstrand L, Brodin P, Bergström G, Uhlén M, Fagerberg L. (2020). Integration of molecular profiles in a longitudinal wellness profiling cohort. Nature communications, 11(1), 1-14.
https://www.nature.com/articles/s41467-020-18148-7 - Sjöstedt E, Zhong W, Fagerberg L, Karlsson M, Mitsios N, Adori C, Oksvold P, Edfors F, Limiszewska A, Hikmet F, Huang J, Du Y, Lin L, Dong Z, Yang L, Liu X, Jiang H, Xu X, Wang J, Yang H, Bolund L, Mardinoglu A, Zhang C, von Feilitzen K, Lindskog C, Pontén F, Luo Y, Hökfelt T, Uhlén M, Mulder J. (2020). An atlas of the protein-coding genes in the human, pig, and mouse brain. Science, 367 (6482)
https://www.science.org/doi/10.1126/science.aay5947 - Uhlén M, Karlsson MJ, Zhong W, Tebani A, Pou C, Mikes J, Lakshmikanth T, Forsström B, Edfors F, Odeberg J, Mardinoglu A, Zhang C, von Feilitzen K, Mulder J, Sjöstedt E, Hober A, Oksvold P, Zwahlen M, Ponten F, Lindskog C, Sivertsson Å, Fagerberg L, Brodin P. (2019). A genome-wide transcriptomic analysis of protein-coding genes in human blood cells. Science, 366 (6472)
https://www.science.org/doi/10.1126/science.aax9198 - Hou J#, Li Z#, Zhong W#, Hao Q, Lei L, Wang L, Zhao D, Xu P, Zhou Y, Wang Y, Xu T. (2017). Temporal transcriptomic and proteomic landscapes of deteriorating pancreatic islets in type 2 diabetic rats. Diabetes, 66(8), 2188-2200 (# equal contribution)
https://diabetes.diabetesjournals.org/content/66/8/2188