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Deep Brain Stimulation

Neuro probe
Financially supported by the Swedish Foundation for Strategic Research

Deep brain stimulation (DBS) is an important therapy for movement disorders such as Parkinson’s disease and essential tremor, and DBS is expanding towards psychiatric illness.

Deep brain stimulation (DBS) is an important therapy for movement disorders and DBS is expanding towards psychiatric illness. The mechanism of action is investigated by combining computer simulations, physiological measurements, imaging and clinical evaluations. Disorders of interest are Parkinson’s disease, essential tremor, and new indications and targets where DBS is introduced.

A patient-specific modelling and simulation software using the finite element method (FEM) for investigation of the electric field around DBS electrodes has been developed. It is used with clinical evaluations of movement in Parkinson’s disease and essential tremor and is now introduced for new symptoms, brain targets and lead designs. ELMA, DBSim and DBViS are open access apps developed by us. These can be requested through our web. DBViSis is a 3D Slicer software for visualization of study results. With ELMA and DBSim own simulations can be set up. Present work focuses on group analysis of DBS volume of tissue activated (VTA) and prediction of DBS stimulation parameters.

Apps

Neuroengineering download

Neuroengineering downloads

Download of APPs are available for patient-specific modeling, simulations and visualization of the electric field around deep brain stimulation (DBS) leads.

Publications

Neuroengineering lab thesis

Neuroengineering publications

A list of publications from the Neuroengineering group at the Department of Biomedical Engineering (IMT) can be found here.

Financially supported by

Swedish Foundation for Strategic Research

Swedish Foundation for Strategic Research (SSF)

Supports research in science, engineering and medicine for the purpose of strengthening Sweden´s future competitiveness. SSF provided funding of around SEK 600 million per annum and has a capital of approx. 11 billion as a basis for its activities.

Swedish Foundation for Strategic Research
Logotype Swedish Research Council

The Swedish Research Council

The Swedish Research Council is an agency under the Ministry of Education, which has a leading role to develop the highest scientific quality research in Sweden and thereby contribute to the development of society.

The Swedish Research Council
Logotype Region Östergötland.

Region Östergötland

ALF is an agreement between the Swedish state and some county councils on cooperation on basic education of doctors, medical research and health care development.

Region Östergötland ALF agreement

Organisation

Institutionen för medicinsk teknik

Department of Biomedical Engineering (IMT)

A national centre for research, PhD studies and graduate studies within biomedical engineering, since 1972.
Neuroengineering

Neuroengineering

A cross disciplinary research field combining engineering and neuroscience. The focus is set on deep brain stimulation (DBS), neuronavigation, optical measurement techniques, brain microcirculation, neuroimaging and neuromodelling.
Two doctors is standing in front of a screen where a disection of a brain is visible.

Neuroengineering

Neuroengineering is a cross-disciplinary research area where engineering meets neuroscience. New methods, tools and techniques are developed and translated for clinical use. The research contributes to new knowledge of the human brain.

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