The neurointensive care unit (NICU) is highly specialized in monitoring severe brain damages such as traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH). Cerebral blood flow (CBF) is therefore a parameter of outmost importance to record in NICU. Our specific interest is in cerebral microcirculation parameters monitored with optical techniques and their comparison with conventionally monitored circulatory indicators, Xe-CT, perfusion MRI and microdialysis. The aim of this multiparametric approach is to investigate the possibility to detect vasospasm, progressing into ischemia and brain infarction, and secondary bleedings in brain trauma at an early stage.
Laser Doppler flowmetry and cerebral microcirculation
Cerebral microcirculation can be measured with laser Doppler flowmetry (LDF). Low power laser light is transmitted through an optical fiber to the tissue. In 2005 we introduced LDF in brain surgery in relation to deep brain stimulation (DBS) implantation. We have now adapted LDF to long term monitoring of cerebral perfusion in NICU.