Optical Coherence Tomography (OCT) provides high resolution (~10 µm) 2D and 3D images from the surface and subsurface tissue microstructures with a maximum depth of 3 mm and a surface area of 1 cm2. OCT has so far entered the clinical routine within ophthalmology and cardiovascular imaging and has great potentials for further translational research and implementation in the clinics. In this project, OCT’s potentials for intra-operative and postoperative (laboratory) pathology diagnostics are investigated. The study of OCT’s potential for thyroid pathology diagnosis is available in the below publication list.
- Tissue identification for thyroid and parathyroid surgery: using optical coherence tomography and fluorescence spectroscopy, Pernilla Petersson, Master thesis, 2015.
- Processing of Optical Coherence Tomography Images- Filtering and Segmentation of Pathological Thyroid Tissue, Daniela Koller, Master thesis, 2016.
- Iulian Emil Tampu, Michaela Maintz, Daniela Koller, Kenth Johansson, Oliver Gimm, Arrigo Capitanio, Anders Eklund, and Neda Haj-Hosseini, "Optical coherence tomography for thyroid pathology: 3D analysis of tissue microstructure", Biomed. Opt. Express 11, 4130-4149 (2020).