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Anna Spångeus

Senior Associate Professor

I am associate professor and senior consultant in internal medicine/endocrinology. My research mainly concerns bone health and the prevention of osteoporosis fractures.

Osteoporosis - Skeletal failure

Osteoporosis implies that the skeleton fails to fulfil their normal function to withstand a certain load/violence and can fracture even at low-energy trauma, so-called osteoporosis fracture. Today, bone health is measured with a so-called Dual energy X-ray Absorptiometry (DXA) where a bone density is obtained. In addition, qualitative measurements, such as trabecular and cortical properties could add valuable information on patient’s bone health and future fracture risk. This is, however, not possible in a clinical routine setting today.

Osteoporosis fractures are common, costly and serious both regarding excess mortality and a risk of lifelong pain and permanent disabilities. At the same time, the disease is currently underdiagnosed and undertreated both regarding pharmacological and non-pharmacological treatment. Fracture Liaison Services (FLS) are built to secure the identification and treatment of risk individuals for osteoporosis. New innovative pathways are important to improve and secure these FLS to ensure that these risk patients are correctly identified, diagnosed and treated optimally from a holistic perspective.

In our research, we look at several links in the FLS, both in terms of identification/diagnostics (new radiological techniques and clinical flows) as well as treatment (drug compliance, patient education and training).

About me

CV

  • Senior consultant (2021)
  • Associate Professor (2020)
  • Senior Lecturer (2012)
  • Specialist internal medicine (2012) and endocrinology and diabetology (2014)
  • Post-doc Imperial College, London, UK (2005/2006)
  • MD (2005)
  • PhD (1999)

Field of Teaching

  • Medical programme: Lectures/seminars in calcium disorders and osteoporosis
  • Medical programme: Former Chair of the Tema CREN (courses 2, 3, 6 and 7), until 2020.

Awards/Assignments

  • Head of Research NSC from 2021
  • Vice Chairman of the Council for Patient and Resident Participation fr.o.m. HT 21
  • Member of the Research Council fr.o.m. HT21
  • Supervisor 1 PhD-student (internal medicine/endocrinology, finished 2020)
  • Co-supervisor 5 PhD students (3 ongoing, 2 finished 2012 and 2010, respectively)
  • Kandidate Kork Prize 2020
  • Andreas Rousseau's Prize 2020 ("best lecture of the year at the medical programme")

Publications

Emese Toth, Jonas Banefelt, Kristina Akesson, Anna Spångeus, Gustaf Ortsater, Cesar Libanati (2020)

Journal of Bone and Mineral Research , Vol.35 , s.861-868 Continue to DOI

J. Banefelt, K. E. Akesson, Anna Spångeus, O. Ljunggren, L. Karlsson, O. Strom, G. Ortsater, C. Libanati, E. Toth (2019)

Osteoporosis International , Vol.30 , s.601-609 Continue to DOI

Anna Spångeus, Simon Johansson, Mischa Woisetschläger (2020)

ARCHIVES OF OSTEOPOROSIS , Vol.15 Continue to DOI

2025

Anna Spångeus, Evangelia Baldimtsi, Maria Lindblom, Christoph Salzlechnar, Tomas Bjerner, Mischa Woisetschläger (2025) The VertAIdo-Project (Vertebral Fracture Ai Detection For Better Osteoporosis Care): Implementation Of AI-Screening In Clinical Routine - First Month Data
Anna Spångeus, Agathi Constantinou, Yvonne Lindbäck, Ann-Charlotte Grahn Kronhed, Jenny Forsberg, Anna Spångeus (2025) PATOS (Patient education in osteoporosis) Feasibility and effectiveness of a digital patient education program in improving self-care in patients with osteoporosis - a pilot study
Anna Spångeus, Tomas Bjerner, Maria Lindblom, Christoph Goetz, Allan Hummer, Christoph Salzlechner, Mischa Woisetschläger (2025) Breaking the silence: AI's contribution to detecting vertebral fractures in opportunistic CT scans in the elderly-a validation study ARCHIVES OF OSTEOPOROSIS, Vol. 20, Article 42 (Article in journal) Continue to DOI
Nadja Fries, Angeliki Kotti, Mischa Woisetschläger, Anna Spångeus (2025) Using CT imaging to identify sarcopenia as a risk factor for severe falls in older adults BMC Geriatrics, Vol. 25, Article 72 (Article in journal) Continue to DOI

2024

Benjamin Klintstrom, Anna Spångeus, Alexandr Malusek, Alexander Synek, Mischa Woisetschläger, Dieter Pahr, Eva Klintström (2024) Automated bone property analysis using corrected in vivo dental cone-beam CT data of human wrists Scientific Reports, Vol. 14, Article 30466 (Article in journal) Continue to DOI

Organisation