Photo of Judit Svensson Arvelund

Judit Svensson Arvelund

Assistant Professor

Our aim is to uncover the role of the immune system in the development of lymphomas and other cancers and use this knowledge to develop and improve cancer immunotherapies.

Tumor Immunology and Immunotherapy Lab

During the last decade, immunotherapy has revolutionized cancer treatment and has shown great success in a subset of patients and cancers.

However, we have only just begun to understand how the complex interactions between cancer cells and the immune system can be exploited to develop efficient immunotherapies.

The aims of our research are to uncover the cellular and molecular mechanisms that predispose to systemic and long-term anti-tumor immunity and the mechanisms that drive resistance to immunotherapy. In particular, we are studying how oncolytic virotherapy can be used in synergy with immunotherapy to achieve optimal immunity against tumors.

A major focus of the lab is to understand the specific role of different types of antigen-presenting cells in priming efficient anti-tumor T cell responses and how this process can be empowered to improve treatment outcomes.

We also aim to study the impact of tumor heterogeneity and tissue-specific microenvironments on the response to therapy. To address these questions we combine in vitro studies, experimental mouse models, patient material and cutting-edge technologies.

Our goal is that our research will contribute to the development of safe and more efficient treatment strategies for patients that currently do not benefit from standard therapies.


Publications

Selected publications

Cover of publication ''
Mark Aleynick, Judit Svensson-Arvelund, Gvantsa Pantsulaia, Kristy Kim, Samuel A. Rose, Ranjan Upadhyay, Michael Yellin, Henry Marsh, Daniel Oreper, Suchit Jhunjhunwala, Christine Carine Moussion, Miriam Merad, Brian D. Brown, Joshua D. Brody (2023)

Journal for ImmunoTherapy of Cancer , Vol.11 Continue to DOI

Cover of publication ''
Judit Svensson-Arvelund, Sara Cuadrado-Castano, Gvantsa Pantsulaia, Kristy Kim, Mark Aleynick, Linda Hammerich, Ranjan Upadhyay, Michael Yellin, Henry Marsh, Daniel Oreper, Suchit Jhunjhunwala, Christine Moussion, Miriam Merad, Brian D. Brown, Adolfo Garcia-Sastre, Joshua D. Brody (2022)

Nature Communications , Vol.13 Continue to DOI

Cover of publication ''
Matthew J. Lin, Judit Svensson-Arvelund, Gabrielle S. Lubitz, Aurelien Marabelle, Ignacio Melero, Brian D. Brown, Joshua D. Brody (2022)

NATURE CANCER , Vol.3 , s.911-926 Continue to DOI

To see more publications visit my profile on Scopus.

Funding

I am funded by:

Swedish Society for Medical Research (SSMF)

Swedish Research Council (VR)

 

Åke Wibergs Stiftelse

Magnus Bergvalls Stiftelse


Areas of strength

Organisation