In my research, I try to understand the very fine molecular details of how mutations impair ion channel function. I also aim to develop new pharmacological avenues to restore the function of these ion channels.
My research group works with ion channels that play important roles in the heart, nervous system and muscle tissue. However, I am particularly interested in cardiac ion channels. Mutations in these ion channels cause cardiac arrhythmias in patients, such as atrial and ventricular fibrillation, which may cause sudden cardiac death. How specific mutations cause cardiac arrhythmia is not known for many mutations and there is no medical drug that restores the function of these channels. My hope is that our research will contribute to improved treatments for these arrhythmias and related disorders.
My research group works with ion channels that play important roles in the heart, nervous system and muscle tissue. However, I am particularly interested in cardiac ion channels. Mutations in these ion channels cause cardiac arrhythmias in patients, such as atrial and ventricular fibrillation, which may cause sudden cardiac death. How specific mutations cause cardiac arrhythmia is not known for many mutations and there is no medical drug that restores the function of these channels. My hope is that our research will contribute to improved treatments for these arrhythmias and related disorders.
