Postdoc in ion channel physiology

Work assignments 

You will work on a project aimed at understanding endogenous regulation of ion channels and electrical excitability, and how this is impacted in disease and by pharmaceutical compounds. You will participate in studies of the effect on compounds on voltage-gated ion channels and cellular excitability, to contribute insights into physiological, pathological and pharmaceutical effects. In terms of experimental approaches, you will primarily use molecular biology techniques as well as electrophysiological techniques in cellular systems (like oocytes from Xenopus oocytes and mammalian cells). You will also implement techniques for recapitulating beta adrenerg stimulation in experimental models and for monitoring trafficking of ion channels.  You will study both healthy wild type channels and ion channels carrying disease-associated mutations.

Qualifications

We are looking for someone with a PhD degree in medical sciences or similar. Good knowledge in electrophysiology, ion channel physiology and ion channel pharmacology is a must, which includes experience of the use of electrophysiology to provide mechanistic insights into how endogenous modulators and genetic variants affect ion channels and cellular excitability.  Moreover, extensive experience of expressing ion channels in oocytes from Xenopus laevis, using two-electrode voltage clamp, electrophysiological analysis, and site directed mutagenesis are a must. Experience of cell cultivation, experimental work with peptide toxins, and experimental modulation of endocannabinoid signaling are considered a merit.

We seek you who are structured, independent, keen on high quality, and with good ability to collaborate.

The position requires good skills in English, both written and spoken.

The workplace

You will work at the Division of Cell- and Neurobiology, CNB, in the group of Sara Liin. The research group is focused on ion channels in cardiac, neuronal and smooth muscle tissue. They aim to understand how endogenous molecules and genetic variants affect ion channel function, and develop compounds rescuing abnormal ion channel function. You will be a team member who interacts closely with other team members using complementary techniques. You will also interact with local technical platforms as well as national and international collaborators.

The employment

This employment is a temporary contract of two years with the possibility of extension up to a total maximum of three years. The employment is full-time, starting by agreement.

Salary and employment benefits

The university applies individual salaries.

More information about employee benefits is available here.

Union representatives

Information about union representatives, see Help for applicants.

Application procedure

Apply for the position by clicking the “Apply” button. Your application must be received no later than 27th of october 2025.
 
Applications and documents received after the date above will not be considered. 
 
Please attach your selected research publications electronically, in pdf or word format, in the application template. Research publications, e.g. monographs, which cannot be sent electronically should be sent in three sets by mail to the University Registrar at Linköping University, University Registrar, S-581 83 Linköping, Sweden. The publications must be received by Linköping University no later than the deadline for application. 

Please note that printed publications will not be returned. They will be archived at Linköping University. 
 
In the event of a discrepancy between the English translation of the job announcement and the Swedish original, the Swedish version shall take precedent.