Photo of Sophia Bäck

Sophia Bäck

PhD student

I’m a Phd student researching the blood flow in the heart using computational fluid dynamics. The focus of my project is thrombus formations in patients with atrial fibrillation.

How does atrial fibrillation alter the blood flow in the heart?

Arial fibrillation (AF) is a very common diseases of the heart. It is characterized by an irregular contraction of the atria of the heart. This changed motion can lead to blood coagulation, which can cause stroke. In my project, I want to understand how the motion of the left atrium influences the blood flow and how the blood flow is changed in patients with atrial fibrillation.

I focus especially on a structure in the left atrium called left atrial appendage (LAA). The shape and motion of left atrial appendage differs a lot between people and it’s in this region of the heart where most thrombi form.

To look at the heart of patients, I use time-resolved computed tomography (CT) images. These images have a high resolution, but they do not provide direct velocity information. Using the computing power from the National Supercomputer Centre in Sweden (NSC), I calculate the velocity of blood inside the heart based on the high-resolution CT images.

Photo of a heart..

About me

CV

  • PhD student in Medical Sciences, Linköping University. Since November 2019.
  • Research Engineer, CMR group, Linköpings University. August 2018 - October 2019.
  • M.Sc. Mechanical Engineering, RWTH Aachen University, Germany. October 2016 - June 2018.
  • B.Sc. Mechanical Engineering, RWTH Aachen University, Germany. October 2012 - September 2016.

Fields of Teaching

  • Course assistant for Physiological Pressures and Flows (TBMT09)

Networks

  • CMR group
  • CMIV research school
  • Liu CircM

Publications

Cover of publication ''
Jonas Lantz, Sophia Bäck, Carljohan Carlhäll, Ann F. Bolger, Anders Persson, Matts Karlsson, Tino Ebbers (2021)

Journal of Biomechanics , Vol.116 Continue to DOI

2024

Sophia Bäck, Jonas Lantz, Iulia Skoda, Lilian Henriksson, Anders Persson, Lars Karlsson, Carljohan Carlhäll, Tino Ebbers (2024) Comprehensive left atrial flow component analysis reveals abnormal flow patterns in paroxysmal atrial fibrillation American Journal of Physiology. Heart and Circulatory Physiology, Vol. 326, p. H511-H521 (Article in journal) Continue to DOI

2023

Sophia Bäck, Iulia Skoda, Jonas Lantz, Lilian Henriksson, Lars Karlsson, Anders Persson, Carljohan Carlhäll, Tino Ebbers (2023) Correction: Elevated atrial blood stasis in paroxysmal atrial fibrillation during sinus rhythm: a patient-specific computational fluid dynamics study (vol 10, 1219021, 2023) Frontiers in Cardiovascular Medicine, Vol. 10, Article 1301605 (Article in journal) Continue to DOI
Linus Ohlsson, André Da Luz Moreira, Sophia Bäck, Jonas Lantz, Carljohan Carlhäll, Anders Persson, Kristofer Hedman, Michelle Chew, Nils Dahlström, Tino Ebbers (2023) Enhancing students understanding of cardiac physiology by using 4D visualization Clinical anatomy (New York, N.Y. Print), Vol. 36, p. 542-549 (Article in journal) Continue to DOI
Sophia Bäck, Iulia Skoda, Jonas Lantz, Lilian Henriksson, Lars Karlsson, Anders Persson, Carljohan Carlhäll, Tino Ebbers (2023) Elevated atrial blood stasis in paroxysmal atrial fibrillation during sinus rhythm: a patient-specific computational fluid dynamics study Frontiers in Cardiovascular Medicine, Vol. 10, Article 1219021 (Article in journal) Continue to DOI
Sophia Bäck, Lilian Henriksson, Ann F Bolger, Carljohan Carlhäll, Anders Persson, Matts Karlsson, Tino Ebbers (2023) Assessment of transmitral and left atrial appendage flow rate from cardiac 4D-CT Communications Medicine, Vol. 3, Article 22 (Article in journal) Continue to DOI

Research

Coworkers

Organisation