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Tino Ebbers

Professor

Novel diagnostic techniques, with more focus on blood flow and tissue characteristics and function, will lead to better diagnosis and treatment of cardiovascular diseases.

Quantification and visualization of blood flow dynamics and tissue characteristics

My research interest is in cardiovascular imaging, with focus on the assessment of blood flow dynamics and tissue characteristics.

Blodflöde genom ett hjärta avbildat på en iPad.Foto: Oskar Lüren

The primary purpose of the cardiovascular system is to drive, control and maintain blood flow to all parts of the body. Today, cardiovascular diagnostics relies almost exclusively on function estimation based on the morphology of chambers and vessels. Cardiac and vascular wall motion are often deduced from the morphological images, and not measured directly. Flow characteristics are mainly assumed.


The focus of my research group is to develop the next generation of methods for the non-invasive assessment of cardiovascular diseases and therapies by focusing on blood flow dynamics and wall characterization in health and disease.

We aim to develop quantitative techniques for the assessment of blood flow, wall motion and tissue characteristics. The majority of the methods are based on magnetic resonance imaging, which allows for non-invasive measurement of velocity and displacement in all directions and dimensions, as well as quantitative tissue characterization in the human body and many materials. Recently, we have also managed to obtain functional information, as blood flow and myocardial function, from computer tomography data using advanced image processing and simulations. By utilizing the techniques across a range of basic biological science investigations, mechanical devices, and clinical questions, we intend to increase the knowledge about the role of blood flow and wall motion in the cardiovascular system. With this translational research approach, we expect to improve the in-depth understanding and diagnostics of cardiovascular disease and treatment strategies.

CV

Positions and degrees

  • 2015 Visiting professor, University of California in San Francisco, CA, USA

  • 2011 Professor in Physiological Measurements
  • 2007 Docent in Biomedical Modelling and Simulation 
  • 2002 – 2004 Predevelopment Engineer, Philips Medical Systems, Netherlands

  • 2001 Doctor of Philosophy (PhD) in Biomedical Engineering

  • 1996 Master of Science (MSc) in Electrical Engineering

 

Recent assignments

  • 2021 - Chair Strategic area Circulation and Metabolism (LiU-CircM)
  • 2021 - Board, Faculty of Medicine and Health Sciences, Linköping University
  • 2020 - Research Council of the Center for Medical Image Science and Visualization
  • 2007 - Co-director, Cardiovascular Magnetic Resonance Group

Education

  • Examiner for the course Physiological pressures and flows (TBMT09)
  • Examiner Master projects Biomedical Engineering (TQMD30/33)
  • Examiner Master projects Electrical Engineering (TQET30/33)

Publications

2024

Linus Ohlsson, Mårten Sandstedt, Joanna-Maria Papageorgiou, Anders Svensson, Ann F. Bolger, Éva Tamás, Hans Granfeldt, Tino Ebbers, Jonas Lantz (2024) Haemodynamic significance of extrinsic outflow graft stenoses during HeartMate 3™ therapy. European heart journal. Imaging methods and practice, Vol. 2, p. qyae082-, Article qyae082 (Article in journal) Continue to DOI
Linus Ohlsson, Joanna-Maria Papageorgiou, Tino Ebbers, Meriam Åström Aneq, Eva Tamas, Hans Granfeldt (2024) Enhancing echocardiographic hemodynamic monitoring in HeartMate 3™ therapy: insights and future directions ESC Heart Failure (Article in journal) Continue to DOI
Federica Viola, Mariana Bustamante, Ann F Bolger, Jan Engvall, Tino Ebbers (2024) Diastolic function assessment with four-dimensional flow cardiovascular magnetic resonance using automatic deep learning E/A ratio analysis Journal of Cardiovascular Magnetic Resonance, Vol. 26, Article 101042 (Article in journal) Continue to DOI
Bente Konst, Linus Ohlsson, Lilian Henriksson, Mårten Sandstedt, Anders Persson, Tino Ebbers (2024) Optimization of photon counting CT for cardiac imaging in patients with left ventricular assist devices: An in-depth assessment of metal artifacts Journal of Applied Clinical Medical Physics (Article in journal) Continue to DOI
Carl Edin, Mattias Ekstedt, Markus Karlsson, Bertil Wegmann, Marcel Warntjes, Eva Swahn, Carl Johan Östgren, Tino Ebbers, Peter Lundberg, Carl-Johan Carlhäll (2024) Liver fibrosis is associated with left ventricular remodeling: insight into the liver-heart axis European Radiology (Article in journal) Continue to DOI

Research

Two scientists are sitting infront of an MRI

Cardiovascular imaging and modeling - CIM

CIM:s tvärvetenskapliga forskningskluster syftar till att öka förståelsen för det kardiovaskulära systemet i hälsa och sjukdom genom utveckling och tillämpning av nya bildbaserade metoder för bedömning av funktion, hemodynamik och vävnadens karaktär.

HEART4FLOW-puff

HEART4FLOW

The objective of the HEART4FLOW project is to develop the next generation of methods for the non-invasive quantitative assessment of cardiac diseases and therapies by focusing on 4D blood flow dynamics.

Assessment of Cardiovascular Blood Flow Using 4D Flow MRI

Assessment of Cardiovascular Blood Flow

Analysing the heart ads an extra dimension to the imaging since it is in constant motion. The project is working on optimizing the accuracy, measurement time, and robustness of 4D flow MRI for clinical use in the near future.

Two scientists are sitting infront of an MRI

Center for Medical Image Science and Visualization (CMIV)

CMIV conducts focused front-line research providing solutions to tomorrow’s clinical issues. The CMIV mission is to develop future methods and tools for image analysis and visualization for applications within health care and medical research.

Viruvian man

Circulation and metabolism - CircM

CircM is a strategic research network for researchers at Linköping University and Region Östergötland within the research field circulation and cardio-metabolic risk factors.

Blood vessels

The Heart and Blood Vessels

The cardiovascular system is a fascinating organ system whose task is to supply all the body’s organs with oxygen and nutrients, as well as carrying away waste products.

Organisation

News