Research on B-cell chronic lymphocytic leukemia (CLL), the most frequent leukemia in western world

Copyright Lennart Nilsson, Cellmaterial Anders Rosén Foto: Copyright Lennart Nilsson, cell material Anders Rosén

We are investigating novel signalling pathways and the influence of redox-regulation in chronic lymphocytic leukemia (CLL). 

Our research team is exploring the phenomena of anergy (immunological unresponsiveness) upon exposure of microbial and self-antigens, as well as synergy (microenvironmental support) in the leukemogenesis of CLL.

Publications

2018

Björn Ingelsson, Daniel Söderberg, Tobias Strid, Anita Söderberg, Ann-Charlotte Bergh, Vesa-Matti Loitto, Kourosh Lotfi, Mårten Segelmark, Giannis Spyrou, Anders Rosén

Lymphocytes eject interferogenic mitochondrial DNA webs in response to CpG and non-CpG oligodeoxynucleotides of class C

In Proceedings of the National Academy of Sciences of the United States of America

Article in journal

Jonas Blomberg, Carl-Gerhard Gottfries, Amal Elfaitouri, Muhammad Rizwan, Anders Rosén

Infection Elicited Autoimmunity and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: An Explanatory Model

In Frontiers in Immunology

Article in journal

2017

Maria Russo, Alfonsina Milito, Carmela Spagnuolo, Virginia Carbone, Anders Rosén, Paola Minasi, Fabio Lauria, Gian Luigi Russo

CK2 and PI3K are direct molecular targets of quercetin in chronic lymphocytic leukaemia.

In OncoTarget

Article in journal

My reseach in media

Publications in ORCHID

Research

About me

Collaboration 

We collaborate with several groups including:

  • Prof Richard Rosenquist, Uppsala
  • Prof Kostas Stamatopoulos, Greece
  • Prof Sohvi Hörkkö, Finland
  • Prof Giannis Spyrou, LiU
  • Prof Mårten Segelmark, LiU
  • Prof Mikael Lindgren, LiU
  • Ass. Prof. Anette Gjörloff

Networks

  • Board member of Swedish CLL group
  • Reviewer for Swedish Cancer Society
  • PhD thesis evaluation committees
  • PhD thesis opponent
  • Reviewer for International Hematology Journals 
  • PhD tutor

More

Teaching program: PhD scientific literature courses – journal club

Discovery of the year 2009, awarded by the Swedish Cancer Association

Social media

Related Research

Organisation