PAINOMICS® Research Group

PAINOMICS Research Group
PAINOMICS Research Group Emma Busk Winquist

The aim of the research at Painomics laboratory is to investigate biomarkers of nociception and pain, at peripheral and central levels in subjects with chronic pain conditions, using omics.

Identification of pain modulating substances and their associated molecular mechanisms is necessary to understand the pathophysiology behind chronic pain. Our research contributes to the development of mechanism-based pain diagnoses and in the long term contributes to the development of more effective treatment methods.

The PAINOMICS research group has a strong track record in the field of musculoskeletal and neuropathic pain research. The research group consists of clinical and preclinical researchers that together investigate following areas:

  • Identification of single or a panel of multiple biomarkers that reflect the molecular signature of chronic pain
  • Identifying molecular biomarker profiles (patterns of proteins, lipids, algesics and inflammation substances) for different chronic pain conditions, e.g., neuropathic pain, chronic back pain, chronic widespread pain/fibromyalgia
  • Analyze if the balance between pain excitatory and inhibitory substances differs between different chronic pain conditions
  • Investigate the correlations between levels of spinal and peripheral pain excitatory/inhibitory substances and clinical characteristics of pain e.g., duration, intensity, anatomical spreading in the body and signs of sensitization/hyperexcitability

Dissertations from the Research Group