Photo of Henrik Green

Henrik Green

Professor

My research aims to better understand the mechanism of action and toxicity of new psychoactive substances, drugs of abuse and cancer chemotherapy including prediction models. I also work on how to solve murders using post-mortem metabolomics and AI.

Presentation

Genetics and Toxicology in Cancer Chemotherapy and Forensic Sciences

My research is focused on finding predictive markers and understanding how pharmaceutiacls and drugs yield desired and undesired effects in humans.

Everyone is different and everyone reacts differently to drugs. Our research group studies how genetic variation affects the effect and risk of side effects in cancer treatment. We also work with new psychoactive drugs (internet drugs), their toxicology and pharmacology. Our third track is genetics in a forensic perspective.

Publications

2023

Hakon Blomstrand, Hans Olsson, Henrik Green, Bergthor Björnsson, Nils Elander (2023) Impact of resection margins and para-aortic lymph node metastases on recurrence patterns and prognosis in resectable pancreatic cancer - a long-term population-based cohort study HPB, Vol. 25, p. 1531-1544 Continue to DOI
Emma Adolfsson, Daniel Kling, Cecilia Gunnarsson, Jon Jonasson, Henrik Green, Anna Green (2023) Whole exome sequencing of FFPE samples - expanding the horizon of forensic molecular autopsies International journal of legal medicine, Vol. 137, p. 1215-1234 Continue to DOI
Matilda Backberg, Svante Vikingsson, Joakim Strandberg, Sara Wall, Anna Åstrand, Hanna Karlsson, Mattias Persson, Robert Kronstrand, Henrik Green (2023) Using in vitro receptor activity studies of synthetic cannabinoids to support the risk assessment of new psychoactive substances-A Swedish strategy to protect public health from harm Forensic Science International, Vol. 348, Article 111691 Continue to DOI
Steven R. Baginski, Tobias Rautio, Lorna A. Nisbet, Karin Lindbom, Xiongyu Wu, Johan Dahlén, Craig Mckenzie, Henrik Green (2023) The metabolic profile of the synthetic cannabinoid receptor agonist ADB-HEXINACA using human hepatocytes, LC-QTOF-MS and synthesized reference standards Journal of Analytical Toxicology Continue to DOI
Shimpei Watanabe, Steven Baginski, Takahiro Iwai, Ritsuko Matsushita, Masahisa Takatsu, Toshio Nakanishi, Karin Lindbom, Craig Mckenzie, Svante Vikingsson, Robert Kronstrand, Henrik Gréen, Yasuo Seto (2023) Systematic In Vitro Metabolic Profiling of the OXIZID Synthetic Cannabinoids BZO-4en-POXIZID, BZO-POXIZID, 5F-BZO-POXIZID, BZO-HEXOXIZID and BZO-CHMOXIZID Journal of Analytical Toxicology, Vol. 47, p. 455-463 Continue to DOI

News

Three men and a woman outside Campus US.

SciLifeLab establishes a new research site at LiU

Technology, expertise, methods and initiatives can be coordinated more within and between higher education institutions. Linköping University is now one of four new sites in the Swedish research infrastructure SciLifeLab.

Male researcher in lab, blue background light.

SEK 13 million for research into solving murders using AI

Was it murder, poisoning or was the death maybe caused by disease? Researchers have now been granted SEK 13 million from the Swedish Research Council to develop a methodology to solve crimes using detailed analyses and artificial intelligence.

Male researcher in lab, blue background light.

Faster narcotics classification of Internet drugs with new method

NPS, new psychoactive substances, are substances developed to affect the brain in a similar way to illegal drugs. Researchers have set up a rapid method for measuring the effect of new NPS and provide scientific basis for narcotics classification.

Networks and collaborations

Research videos

The hunt for the new drug - Sverige forskar

The drug trade is usually one step ahead of the legislators because each preparation must be classified as a drug separately before they are banned. But now the researchers at Linköping University can make the hunt for the drugs go much faster.

Internet drugs – occurrence, pharmacology and classificationas narcotic drugs

How dangerous are internet drugs really and how do they spread in society? Henrik Gréen, professor of forensic sciences, talks about the never-ending influx of new drugs, and about how his and others‘ research makes a difference in getting drugs classed as narcotic drugs and protecting lives.

About me

CV

Currently:

  • Professor in forensic sciences at Division of Clinical Chemistry and Pharamcology, Department of Biomedical and Clinical Sciences, Faculty of Medical Sciences, Linköping University.
  • Researcher / Molecular Biologist in Engineering and Genomics. Department of Forensic Genetics and Forensic Toxicology, National Board of Forensic Medicine, Linköping.

Previously:

  • 2012 - 2020: Research strategist / Molecular Biologist in Engineering and Genomics. Department of Forensic Genetics and Forensic Toxicology, National Board of Forensic Medicine, Linköping and associated with Linköping University
  • 2011 - 2012: Post-doc at Science for Life Laboratory, Division of Gene technology, Institution for Biotechnology, KTH - Royal Institute of Technology.
  • 2007 - 2012: Assistant Professor at the Division of Drug Research, Linköping University, Linköping Sweden.

Education

  • 2000 - Master of Science in Engineering Biology. Institute of Technology, Linköping University, Linköping, Sweden.    
  • 2007 - PhD in Clinical Pharmacology. Division of Clinical Pharmacology, Department of medicine and Care, Faculty of Health Sciences, Linköping University, Linköping, Sweden. 
  • 2012 - Associate Professor in Pharmacogenetics at Linköping University.

Co-workers

Organisation