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Henrik Green

Deputy Head of Department, Professor

My research aims to better understand the mechanism of action and toxicity of new psychoactive substances, drugs of abuse and cancer chemotherapy including prediction models. I also work on how to solve murders using post-mortem metabolomics and AI.

Presentation

Genetics and Toxicology in Cancer Chemotherapy and Forensic Sciences

My research is focused on finding predictive markers and understanding how pharmaceuticals and drugs yield desired and undesired effects in humans.

Everyone is different and everyone reacts differently to drugs. Our research group studies how genetic variation affects the effect and risk of side effects in cancer treatment. We also work with new psychoactive drugs (internet drugs), their toxicology and pharmacology. Our third track is genetics in a forensic perspective.

Publications

2025

Caitlyn Norman, Kristin Webling, Darta Stalberga, Lisa Maas, Johannes Tveit, Huiling Liu, Shimpei Watanabe, Svante Vikingsson, Henrik Green (2025) In vitro metabolism of Benzyl-4CN-BUTINACA and MDMB-4CN-BUTINACA using human hepatocytes and LC-QToF-MS analysis Archives of Toxicology (Article in journal) Continue to DOI
Anna Wålinder Österberg, Robert Jablonowski, Ingegerd Ostman-Smith, Marcus Carlsson, Todd T. Schlegel, Henrik Green, Cecilia Gunnarsson, Eva Fernlund (2025) Spatial QRS-T angle can indicate presence of myocardial fibrosis in pediatric and young adult patients with hypertrophic cardiomyopathy Journal of Electrocardiology, Vol. 89, Article 153859 (Article in journal) Continue to DOI
Magnus A. B. Axelsson, Hanna Lovgren, Robert Kronstrand, Henrik Green, Moa Andresen Bergstrom (2025) Epidemiology of New Psychoactive Substances in Relation to Traditional Drugs of Abuse in Clinical Oral Fluid Samples Basic & Clinical Pharmacology & Toxicology, Vol. 136, Article e14117 (Article in journal) Continue to DOI
Hakon Blomstrand, Malin Bodarve, Fredrik Groth, Peter Naredi, Malin Sund, Caroline Vilhav, Henrik Green, Bergthor Björnsson, Daniel Ohlund, Stina Lindblad, Oskar Franklin, Nils Elander (2025) Intratumoural expression of dihydropyrimidine dehydrogenase is an independent prognostic factor in resected pancreatic ductal adenocarcinoma treated with adjuvant gemcitabine Oncology Letters, Vol. 29, Article 99 (Article in journal) Continue to DOI
Daniel Kling, Emma Adolfsson, Henrik Green, Anna Green (2025) The power of hybridization capture - Illustrated using an expanded gene panel on 100 post mortem samples, focusing on sudden unexplained death Forensic Science International: Genetics, Vol. 74, Article 103160 (Article in journal) Continue to DOI

News

Henrik Green.

Nerve damage from cancer treatment can be predicted

Many women treated for breast cancer using taxanes, a type of cytostatic drug, often experience side effects in the nervous system. Researchers at LiU have developed a tool that can predict the risk level for each individual.
Three men and a woman outside Campus US.

SciLifeLab establishes a new research site at LiU

Technology, expertise, methods and initiatives can be coordinated more within and between higher education institutions. Linköping University is now one of four new sites in the Swedish research infrastructure SciLifeLab.
Male researcher in lab, blue background light.

SEK 13 million for research into solving murders using AI

Was it murder, poisoning or was the death maybe caused by disease? Researchers have now been granted SEK 13 million from the Swedish Research Council to develop a methodology to solve crimes using detailed analyses and artificial intelligence.

Networks and collaborations

Sequencing DNA.

Strategic Research Area in Forensic Sciences

The Strategic Research Area in Forensic Sciences is a joint venture between the National Board of Forensic Medicine in Sweden and Linköping University.
Illustrative image of cancer cells and networks.

Cancer

Cancer is a research network for scientists and health care professionals at Linköping University and at the County Council of Östergötland (Region Östergötland). The research is related to cancer diagnosis, pathogenesis and treatment.

Research videos

The hunt for the new drug, screenshot.

The hunt for the new drug - Sverige forskar

The drug trade is usually one step ahead of the legislators because each preparation must be classified as a drug separately before they are banned. But now the researchers at Linköping University can make the hunt for the drugs go much faster.

introduction picture with headshot and title of presentation.

Internet drugs – occurrence, pharmacology and classification as narcotic drugs

How dangerous are internet drugs really and how do they spread in society? Henrik Gréen, professor of forensic sciences, talks about the never-ending influx of new drugs, and about how his and others‘ research makes a difference in getting drugs classed as narcotic drugs and protecting lives.

About me

CV

Currently:

  • Professor in forensic sciences at Division of Clinical Chemistry and Pharmacology, Department of Biomedical and Clinical Sciences, Faculty of Medical Sciences, Linköping University.
  • Researcher / Molecular Biologist in Engineering and Genomics. Department of Forensic Genetics and Forensic Toxicology, National Board of Forensic Medicine, Linköping.

Previously:

  • 2012 - 2020: Research strategist / Molecular Biologist in Engineering and Genomics. Department of Forensic Genetics and Forensic Toxicology, National Board of Forensic Medicine, Linköping and associated with Linköping University
  • 2011 - 2012: Post-doc at Science for Life Laboratory, Division of Gene technology, Institution for Biotechnology, KTH - Royal Institute of Technology.
  • 2007 - 2012: Assistant Professor at the Division of Drug Research, Linköping University, Linköping Sweden.

Education

  • 2000 - Master of Science in Engineering Biology. Institute of Technology, Linköping University, Linköping, Sweden.    
  • 2007 - PhD in Clinical Pharmacology. Division of Clinical Pharmacology, Department of medicine and Care, Faculty of Health Sciences, Linköping University, Linköping, Sweden. 
  • 2012 - Associate Professor in Pharmacogenetics at Linköping University.

Co-workers

Robert Kronstrand

Adjunct Professor

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Martin Josefsson

Adjunct Associate Professor, Docent

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Peter Konradsson
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Johan Dahlén

Associate Professor, Docent

Elisabeth Åvall Lundqvist

Organisation

Division of Clinical Chemistry and Pharmacology (KKF)

The Division of Clinical Chemistry and Pharmacology (KKF) conducts research and education that includes the subject areas of anesthesiology/intensive care, pharmacology and clinical pharmacology, forensic sciences and clinical chemistry.

Department of Biomedical and Clinical Sciences (BKV)

What characterizes the Department of Biomedical and Clinical Sciences (BKV) is the wide breadth of research and education. BKV is one of the largest departments at LiU with affiliation mainly to the Faculty of Medicine and Health Sciences.
Five people in a laboratory.

Faculty of Medicine and Health Sciences (MEDFAK)

The Faculty of Medicine and Health Sciences conducts research and education within medicine, healthcare and public health.

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