Photo of Henrik Green

Henrik Green

Deputy Head of Department, Professor

My research aims to better understand the mechanism of action and toxicity of new psychoactive substances, drugs of abuse and cancer chemotherapy including prediction models. I also work on how to solve murders using post-mortem metabolomics and AI.

Presentation

Genetics and Toxicology in Cancer Chemotherapy and Forensic Sciences

My research is focused on finding predictive markers and understanding how pharmaceutiacls and drugs yield desired and undesired effects in humans.

Everyone is different and everyone reacts differently to drugs. Our research group studies how genetic variation affects the effect and risk of side effects in cancer treatment. We also work with new psychoactive drugs (internet drugs), their toxicology and pharmacology. Our third track is genetics in a forensic perspective.

Publications

2024

Kristina Engvall, Hanna Uvdal, Niclas Björn, Elisabeth Åvall Lundqvist, Henrik Green (2024) Prediction models of persistent taxane-induced peripheral neuropathy among breast cancer survivors using whole-exome sequencing npj Precision Oncology, Vol. 8, Article 102 Continue to DOI
Amanda Holck, Marie Asp, Henrik Green, Asa Westrin, Margareta Reis (2024) CYP2D6 Genotyping and Inhibition as Predictors of Adverse Drug Reactions in Depressive Disorders Journal of Clinical Psychiatry, Vol. 85, Article 23m14937 Continue to DOI
Karin Lindbom, Caitlyn Norman, Steven Baginski, Lucas Krebs, Darta Stalberga, Tobias Rautio, Xiongyu Wu, Robert Kronstrand, Henrik Green (2024) Human metabolism of the semi-synthetic cannabinoids hexahydrocannabinol, hexahydrocannabiphorol and their acetates using hepatocytes and urine samples Drug Testing and Analysis Continue to DOI
Robert Kronstrand, Markus Roman, Henrik Green, Michael T. Truver (2024) Quantitation of hexahydrocannabinol (HHC) and metabolites in blood from DUID cases Journal of Analytical Toxicology Continue to DOI
Joel As, Ilma Bertulyte, Nina Norgren, Anna Johansson, Niclas Eriksson, Henrik Green, Mia Wadelius, Paer Hallberg (2024) Whole genome case-control study of central nervous system toxicity due to antimicrobial drugs PLOS ONE, Vol. 19, Article e0299075 Continue to DOI

News

Three men and a woman outside Campus US.

SciLifeLab establishes a new research site at LiU

Technology, expertise, methods and initiatives can be coordinated more within and between higher education institutions. Linköping University is now one of four new sites in the Swedish research infrastructure SciLifeLab.

Male researcher in lab, blue background light.

SEK 13 million for research into solving murders using AI

Was it murder, poisoning or was the death maybe caused by disease? Researchers have now been granted SEK 13 million from the Swedish Research Council to develop a methodology to solve crimes using detailed analyses and artificial intelligence.

Male researcher in lab, blue background light.

Faster narcotics classification of Internet drugs with new method

NPS, new psychoactive substances, are substances developed to affect the brain in a similar way to illegal drugs. Researchers have set up a rapid method for measuring the effect of new NPS and provide scientific basis for narcotics classification.

Networks and collaborations

Research videos

The hunt for the new drug - Sverige forskar

The drug trade is usually one step ahead of the legislators because each preparation must be classified as a drug separately before they are banned. But now the researchers at Linköping University can make the hunt for the drugs go much faster.

Internet drugs – occurrence, pharmacology and classificationas narcotic drugs

How dangerous are internet drugs really and how do they spread in society? Henrik Gréen, professor of forensic sciences, talks about the never-ending influx of new drugs, and about how his and others‘ research makes a difference in getting drugs classed as narcotic drugs and protecting lives.

About me

CV

Currently:

  • Professor in forensic sciences at Division of Clinical Chemistry and Pharamcology, Department of Biomedical and Clinical Sciences, Faculty of Medical Sciences, Linköping University.
  • Researcher / Molecular Biologist in Engineering and Genomics. Department of Forensic Genetics and Forensic Toxicology, National Board of Forensic Medicine, Linköping.

Previously:

  • 2012 - 2020: Research strategist / Molecular Biologist in Engineering and Genomics. Department of Forensic Genetics and Forensic Toxicology, National Board of Forensic Medicine, Linköping and associated with Linköping University
  • 2011 - 2012: Post-doc at Science for Life Laboratory, Division of Gene technology, Institution for Biotechnology, KTH - Royal Institute of Technology.
  • 2007 - 2012: Assistant Professor at the Division of Drug Research, Linköping University, Linköping Sweden.

Education

  • 2000 - Master of Science in Engineering Biology. Institute of Technology, Linköping University, Linköping, Sweden.    
  • 2007 - PhD in Clinical Pharmacology. Division of Clinical Pharmacology, Department of medicine and Care, Faculty of Health Sciences, Linköping University, Linköping, Sweden. 
  • 2012 - Associate Professor in Pharmacogenetics at Linköping University.

Co-workers

Organisation