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Henrik Green

Deputy Head of Department, Professor

My research aims to better understand the mechanism of action and toxicity of new psychoactive substances, drugs of abuse and cancer chemotherapy including prediction models. I also work on how to solve murders using post-mortem metabolomics and AI.

Presentation

Genetics and Toxicology in Cancer Chemotherapy and Forensic Sciences

My research is focused on finding predictive markers and understanding how pharmaceuticals and drugs yield desired and undesired effects in humans.

Everyone is different and everyone reacts differently to drugs. Our research group studies how genetic variation affects the effect and risk of side effects in cancer treatment. We also work with new psychoactive drugs (internet drugs), their toxicology and pharmacology. Our third track is genetics in a forensic perspective.

Publications

2026

Katharina Elisabeth Grafinger, Wolfgang Weinmann, Daniel Pasin, Henrik Green, Christophe P. Stove, Verena Schoning, Felix Hammann (2026) Machine learning in forensic toxicology: Concepts, applications and challenges in bioanalysis, ADME, and toxicodynamics Forensic Science International, Vol. 383, Article 112883 (Article, review/survey) Continue to DOI
Rasmus Magnusson, Carl Soderberg, Liam Ward, Jenny Arpe, Fredrik Kugelberg, Albert Elmsjö, Henrik Green, Elin Nyman (2026) The human metabolome and machine learning improves predictions of the post-mortem interval Nature Communications, Vol. 17, Article 1504 (Article in journal) Continue to DOI

2025

Kissopoulou Antheia, Eva Fernlund, Jan-Erik Karlsson, Henrik Green, Rada Ellegård, Cecilia Gunnarsson (2025) Genetic determinants of the phenotype in a Swedish cohort of patients with hypertrophic cardiomyopathy Scientific Reports, Vol. 15, Article 39357 (Article in journal) Continue to DOI
Anna Åstrand, Emiliano Laudadio, Prince S. Gameli, Laura Martin, Jeremy Carlier, Francesco P. Busardo, Johan Dahlén, Xiongyu Wu, Peter Konradsson, Svante Vikingsson, Robert Kronstrand, Henrik Green (2025) Structure-activity relationship of prevalent synthetic cannabinoid metabolites on hCB1 in vitro and in silico dynamics Acta Pharmacologica Sinica (Article in journal) Continue to DOI
Henrik Green, Mattias Persson, Maria Wikstrom, Manuela Monti (2025) In vitro monoamine reuptake inhibition and forensic case series in Sweden of the synthetic cathinones 2-, 3-, and 4-Me-alpha-PiHP Forensic Science International, Vol. 377, Article 112657 (Article in journal) Continue to DOI

News

En person i labbrock som håller i en flaska.

AI provides a more precise time of death

Artificial intelligence can be used to provide a more precise time of death, which can be crucial in e.g. murder investigations. The AI model is trained on so-called metabolites in thousands of blood samples from real deaths.

Four LiU researchers recieve funding from the Swedish Cancer Society

Researchers at LiU share SEK 12 million for new projects to improve treatment and quality of life for cancer patients. One of them is Henrik Green, who studies how genetic differences between patients can affect how they react to cancer treatment.
Man wearing a lab coat holds a test tube containing two green pills.

From lab to legislation – the fight against new online drugs

A new drug on the European market – every week. Professor Henrik Green is using research to help government agencies stop the most dangerous online drugs more quickly.

Networks and collaborations

Sequencing DNA.

Strategic Research Area in Forensic Sciences

The Strategic Research Area in Forensic Sciences is a joint venture between the National Board of Forensic Medicine in Sweden and Linköping University.
Illustrative image of cancer cells and networks.

Cancer

Cancer is a research network for scientists and health care professionals at Linköping University and at the County Council of Östergötland (Region Östergötland). The research is related to cancer diagnosis, pathogenesis and treatment.
Campus US with cherry blossom in the foreground.

SciLifeLab Linköping

SciLifeLab Linköping is both a local and a national research infrastructure, with unique technologies and expert competence accessible for academic and industrial researcher in the field of life sciences, health and data-driven life science.

Research videos

The hunt for the new drug, screenshot.

The hunt for the new drug - Sverige forskar

The drug trade is usually one step ahead of the legislators because each preparation must be classified as a drug separately before they are banned. But now the researchers at Linköping University can make the hunt for the drugs go much faster.

introduction picture with headshot and title of presentation.

Internet drugs – occurrence, pharmacology and classification as narcotic drugs

How dangerous are internet drugs really and how do they spread in society? Henrik Gréen, professor of forensic sciences, talks about the never-ending influx of new drugs, and about how his and others‘ research makes a difference in getting drugs classed as narcotic drugs and protecting lives.

About me

CV

Currently:

  • Professor in forensic sciences at Division of Clinical Chemistry and Pharmacology, Department of Biomedical and Clinical Sciences, Faculty of Medical Sciences, Linköping University.
  • Researcher / Molecular Biologist in Engineering and Genomics. Department of Forensic Genetics and Forensic Toxicology, National Board of Forensic Medicine, Linköping.

Previously:

  • 2012 - 2020: Research strategist / Molecular Biologist in Engineering and Genomics. Department of Forensic Genetics and Forensic Toxicology, National Board of Forensic Medicine, Linköping and associated with Linköping University
  • 2011 - 2012: Post-doc at Science for Life Laboratory, Division of Gene technology, Institution for Biotechnology, KTH - Royal Institute of Technology.
  • 2007 - 2012: Assistant Professor at the Division of Drug Research, Linköping University, Linköping Sweden.

Education

  • 2000 - Master of Science in Engineering Biology. Institute of Technology, Linköping University, Linköping, Sweden.    
  • 2007 - PhD in Clinical Pharmacology. Division of Clinical Pharmacology, Department of medicine and Care, Faculty of Health Sciences, Linköping University, Linköping, Sweden. 
  • 2012 - Associate Professor in Pharmacogenetics at Linköping University.

Co-workers

Placeholder for missing image of Robert Kronstrand

Robert Kronstrand

Adjunct Professor

Photo of Martin Josefsson

Martin Josefsson

Adjunct Associate Professor, Docent

Photo of Peter Konradsson

Peter Konradsson

Professor Emeritus

Photo of Johan Dahlén

Johan Dahlén

Associate Professor, Docent

Placeholder for missing image of Elisabeth Åvall Lundqvist

Elisabeth Åvall Lundqvist

Professor Emerita

Organisation

Division of Clinical Chemistry and Pharmacology (KKF)

The Division of Clinical Chemistry and Pharmacology (KKF) conducts research and education that includes the subject areas of anesthesiology/intensive care, pharmacology and clinical pharmacology, forensic sciences and clinical chemistry.

Department of Biomedical and Clinical Sciences (BKV)

What characterizes the Department of Biomedical and Clinical Sciences (BKV) is the wide breadth of research and education. BKV is one of the largest departments at LiU with affiliation mainly to the Faculty of Medicine and Health Sciences.
Five people in a laboratory.

Faculty of Medicine and Health Sciences (MEDFAK)

The Faculty of Medicine and Health Sciences conducts research and education within medicine, healthcare and public health.

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