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Filip Hammaréus

I combine my profession as an intern physician with research on extracellular matrix biomarkers in blood and how these affect the risk for coronary artery disease and ascending aortic dilatation.

The measurement of extracellular matrix biomarkers in blood – a new way to determine cardiovascular risk?

Cardiovascular disease remains the number one cause of morbidity and mortality worldwide.

In spite of enormous scientific breakthroughs in terms of determining cardiovascular risk, the challenge remains on how to fully determine cardiovascular risk for the specific patient. With an aging population and newer, better but also more expensive treatment options, cardiovascular risk estimation is believed to play an even larger role in the future.

Beyond lipids and inflammatory markers, a new type of blood test for cardiovascular risk estimation has emerged in recent years, namely the measurement of extracellular matrix proteins. In our research, we quantify these blood borne markers and explore how the levels are associated with coronary artery disease and ascending aortic dilatation. The goal is to increase the understanding of these proteins in relation to cardiovascular risk and we hope that this could facilitate clinical use in the future.

About me


  • Accepted into medical school LiU autumn 2017
  • Accepted into ”forskarlinjen” spring 2021
  • PhD student since August 2021
  • Degree of Master of Science in Medicine, January 2023
  • Intern Physician region Jönköpings län since February 2023




Filip Hammaréus, Chiara Trenti, Hanna M. Bjorck, Jan Engvall, Hanna Lekedal, Aleksandra Krzynska-Trzebiatowska, David Kylhammar, Marcus Lindenberger, Anna Lundberg, Fredrik Nilsson, Lennart Nilsson, Eva Swahn, Lena Jonasson, Petter Dyverfeldt (2024) Wall shear stress measured with 4D flow CMR correlates with biomarkers of inflammation and collagen synthesis in mild-to-moderate ascending aortic dilation and tricuspid aortic valves European Heart Journal Cardiovascular Imaging Continue to DOI


Filip Hammaréus, Lennart Nilsson, Kwok-Leung Ong, Margareta Kristenson, Karin Festin, Anna K. Lundberg, Rosanna W. S. Chung, Eva Swahn, Joakim Alfredsson, Signe Holm Nielsen, Lena Jonasson (2023) Plasma type I collagen α1 chain in relation to coronary artery disease: findings from a prospective population-based cohort and an acute myocardial infarction prospective cohort in Sweden. BMJ Open, Vol. 13, Article e073561 Continue to DOI

Research projects