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David Kylhammar

Adjunct Associate Professor, Docent

Consultant physician and researcher in cardiovascular and respiratory medicine. I want to better understand who will suffer from cardiovascular diseases such as heart failure, myocardial infarction and sudden death.

Presentation

The Swedish CArdioPulmonary bioImage Study (SCAPIS) is a national population-based study with approx. 30 000 randomly selected participants aged 50-64 years. The participants underwent a comprehensive investigation including imaging by computed tomography of the heart, coronary arteries and thorax, ultrasound of the carotid arteries and pulmonary function tests. They also provided blood samples and filled out extensive questionnaires. The around 5000 participants recuited in 2015-2018 in Linköping additionally underwent an echocardiographic examination and I am the principal investigator of the SCAPIS Linköping echocardiographic study. In 2024-2025 half the study population was re-examined.

The principal aim of SCAPIS is to find new and in our time better ways to predict the risk of cardiovascular diseases and chronic obstructive pulmonary disease. The risk factor distribution in the population is not the same today as it was some decades ago and the development of new technologies has brought new diagnostic possibilities. When we can better predict who is at high risk of a disease, the possibilities for successful preventive measures will improve.

Besides my engagement in SCAPIS, I also conduct research that aim to better understand the rare, but serious disease pulmonary arterial hypertension (PAH) and I am involved in research projects concerning ascending aortic dilation, cardiac involvement in the chronic rheumatic disease systemic lupus erythematosus (SLE) and the assessment of diastolic cardiac function.

About me

CV

  • Medical Doctor, Lund University, 2012
  • Doctor of Philosophy in Medical Science (Clinical Medicine, Cardiology), Lund University, 2016, and Docent in Clinical Physiology, Linköping University 2026
  • Consultant Physician at Linköping University Hospital since 2023
  • Associate Clinical Research Fellow, Wallenberg Centre for Molecular Medicine (WCMM), 2023-
  • Member of the Board of the Swedish Association for Clinical Physiology since 2021 and Secretary in the Scientific Committee 2021-2024
  • Chair of the Organizing Committee for the Swedish Cardiovascular Spring Meeting 2026

Publications

2026

Lina Hult, Kristofer Hedman, Carl Johan Östgren, Jonas Johnson, Fredrik H Nyström, Peter Blomstrand, Jan Engvall, David Kylhammar (2026) Left ventricular mechanical dispersion in a middle-aged population: associations with subclinical cardiac remodelling and cardiovascular risk Open heart, Vol. 13, Article e004114 (Article in journal) https://dx.doi.org/10.1136/openhrt-2026-004114
David Kylhammar, Lina Hult, Peter Blomstrand, Hannes Holm Isholth, Amra Jujic, Martin Magnusson, Carl Johan Östgren, Jan Engvall, Kristofer Hedman (2026) Diastolic dysfunction is equally common in pre-diabetes and diabetes and associated with concomitant cardiometabolic risk factors Open heart, Vol. 13, Article e004052 (Article in journal) https://dx.doi.org/10.1136/openhrt-2026-004052
Suneela Zaigham, Per Liv, Elin Chorell, Annelie Behndig, Apostolos Bossios, Kenneth Caidahl, Anna-Carin Olin, Arne Egesten, Jan Engvall, Jonas Eriksson Strom, Andreas Frolich, Ludger Grote, Anders Gummesson, Viktor Hamrefors, Christer Janson, David Kylhammar, Eva Lindberg, Anders Linden, Mirjam Ljunggren, Hans Lennart Persson, Magnus Skold, Ellen Tufvesson, Lowie Egw Vanfleteren, Andrei Malinovschi, Anders Blomberg (2026) Correction: Plasma proteins associated with cardiovascular disease in relation to lung function in SCAPIS (vol 249, pg 108463, 2025) Respiratory Medicine, Vol. 255, Article 108710 (Article in journal) https://dx.doi.org/10.1016/j.rmed.2026.108710
Johan Korduner, Hannes Holm Isholth, Amra Jujic, Gunnar Engstrom, David Kylhammar, Jan Engvall, Martin Magnusson, Anders Gottsater, Peter M. Nilsson (2026) Clinical characterization of individuals with obesity but normal blood pressure and heart function - a descriptive study from the SCAPIS cohort BMC Cardiovascular Disorders, Vol. 26, Article 180 (Article in journal) https://dx.doi.org/10.1186/s12872-026-05551-z

2025

Suneela Zaigham, Per Liv, Elin Chorell, Annelie Behndig, Apostolos Bossios, Kenneth Caidahl, Anna-Carin Olin, Arne Egesten, Jan Engvall, Jonas Eriksson Strom, Andreas Frolich, Ludger Grote, Anders Gummesson, Viktor Hamrefors, Christer Janson, David Kylhammar, Eva Lindberg, Anders Linden, Mirjam Ljunggren, Lennart Persson, Magnus Skold, Ellen Tufvesson, Lowie Egw Vanfleteren, Andrei Malinovschi, Anders Blomberg (2025) Plasma proteins associated with cardiovascular disease in relation to lung function in SCAPIS Respiratory Medicine, Vol. 249, Article 108463 (Article in journal) https://dx.doi.org/10.1016/j.rmed.2025.108463

Research

Research projects

  • SCAPIS, principal investigator of the echocardiography study in Linköping
  • AscA, ascending aortic dilation
  • Risk assessment in pulmonary arterial hypertension
  • Cardiac affection in systemic lupus erythematosus

Supervisor

Main supervisor to doctoral student Ylva Sjöberg Lind Prediction of cardiovascular risk by novel speckle tracking techniques: Myocardial work and mechanical dispersion

Assistant supervisor to doctoral student Lina Hult Left ventricular deformation and mechanical dispersion, main supervisor is associate professor Peter Blomstrand

Assistant supervisor to doctoral student Katrin Salman Mechanistic evaluation of left ventricular diastolic function, main supervisor is associate professor Eva Tamas

CT scanner at SCAPIS

SCAPIS - The Swedish CArdioPulmonary bioImage Study

SCAPIS combines the use of new imaging technologies, advances in large-scale 'comics' and epidemiological analyses to extensively characterize a Swedish cohort of 30 000 men and women aged between 50 and 64 years.

Organisation

Coworkers

News