Ingrid Asp Kidney Research Center

At the Ingrid Asp Kidney Research Center, patient-oriented kidney research is conducted with a focus on finding new and more effective treatments. The research center is a platform for physicians, nurses and biomedical researchers to connect in order to strengthen kidney research projects locally and support national and international collaboration.

About the research

Kidney disease is more common than previously recognized. By 2040, kidney failure could be the fifth leading cause of death if no action is taken. It is a complex disease with a strong link to cardiovascular disease, where also young kidney patients are disproportionally affected.

There is a great need for more research on disease mechanisms and on how to prevent disease progression. One of the goals of kidney research at LiU is to be able to diagnose and treat patients early.


Timely and more precise treatments can slow the progression to kidney failure and its accompanying complications.
Annette Bruchfeld is Professor in Nephrology and research leader at the center, which is funded by a donation from the Ingrid Asp Foundation for Kidney Research. The center is a node for kidney research with the aim of creating new collaborations and disseminating knowledge about the impact of kidney diseases on public health. Here, seminar series and symposia will also be organized where leading national and international researchers will be invited to promote clinical research and new research findings.

 

Annette Bruchfeld - professor in kidney medicine

Meet the new professor att Linköping University.

More about the donations, Ingrid Asp and the foundation

Selected publications

Cover of publication ''
Daniel Appelgren, Srinivasulu Puli, Thomas Hellmark, Pierre Pochard, Jacques-Olivier Pers, Jan Ernerudh, Per Eriksson, Mårten Segelmark (2023)

Clinical and Experimental Immunology , Vol.213 , s.190-201 Continue to DOI

Cover of publication ''
Gillian Dao Nyesiga, Lieneke Pool, Pavlos C. Englezou, Terese Hylander, Lars Ohlsson, Daniel Appelgren, Anette Sundstedt, Kristina Tillerkvist, Hanne R. Romedahl, Maria Wigren (2023)

Frontiers in Immunology , Vol.14 Continue to DOI

Cover of publication ''
Daniel Appelgren, Kim Maree O´Sullivan (2022)

Frontiers in Immunology , Vol.13 Continue to DOI

Peters B, Beige J, Siwy J, Rudnicki M, Wendt R, Ortiz A, Sanz AB, Mischak H, Reich HN, Nasic S, Mahmood D, Persson A, Fernström A, Weiner M, Stegmayr B; PersTIgAN working group. Dynamics of urine proteomics biomarker and disease progression in patients with IgA nephropathy. Nephrol Dial Transplant. 2023 Nov 30;38(12):2826-2834.

Weiner M, Goh SM, Mohammad AJ, Hrušková Z, Tanna A, Sharp P, Kang A, Bruchfeld A, Selga D, Chocová Z, Westman K, Eriksson P, Harper L, Pusey CD, Tesaŕ V, Salama AD, Segelmark M. Effect of Treatment on Damage and Hospitalization in Elderly Patients with Microscopic Polyangiitis and Granulomatosis with Polyangiitis. J Rheumatol. 2020 Apr;47(4):580-588.

Weiner M, Bjørneklett R, Hrušková Z, Mackinnon B, Poulton CJ, Sindelar L, Mohammad AJ, Eriksson P, Gesualdo L, Geetha D, Crnogorac M, Jayne D, Hogan SL, Geddes C, Tesar V, Aasarød K, Segelmark M. Proteinase 3-and myeloperoxidase-serotype of anti-neutrophil cytoplasmic antibody (ANCA) in relation to demographical factors and geographical distribution in biopsy proven ANCA-associated glomerulonephritis. Nephrol Dial Transplant. 2019 Feb 1;34(2):301-308

Weiner M, Goh S, Mohammad A, Hrušková Z, Tanna A, Bruchfeld, A, Selga D, Chocová Z, Westman K, Eriksson P, Pusey C, Tesaŕ V, Salama A, Segelmark M. Outcome and treatment of elderly patients with anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis. Clin J Am Soc Nephrol. 2015 Jul 7;10(7):1128-35.

Endopeptidase Cleavage of Anti-Glomerular Basement Membrane Antibodies in vivo in Severe Kidney Disease: An Open-Label Phase 2a Study.
Uhlin F, Szpirt W, Kronbichler A, Bruchfeld A, Soveri I, Rostaing L, Daugas E, Lionet A, Kamar N, Rafat C, Mysliveček M, Tesař V, Fernström A, Kjellman C, Elfving C, McAdoo S, Mölne J, Bajema I, Sonesson E, Segelmark M.J Am Soc Nephrol. 2022 Apr;33(4):829-838. doi: 10.1681/ASN.2021111460. Epub 2022 Mar 8

Association of Longitudinal High-Sensitivity Troponin T With Mortality in Patients With Chronic Kidney Disease.
Chesnaye NC, Al-Sodany E, Szummer K, Barany P, Heimbürger O, Almquist T, Melander S, Uhlin F, Dekker F, Wanner C, Jager KJ, Evans M. J Am Coll Cardiol. 2022 Feb 1;79(4):327-336. doi: 10.1016/j.jacc.2021.11.023.

How to needle: A mixed methods study on choice of cannulation technique for arteriovenous fistula.
Staaf K, Fernström A, Uhlin F. J Clin Nurs. 2023 Aug;32(15-16):4559-4573. doi: 10.1111/jocn.16454. Epub 2022 Jul 10.

Time-averaged concentration estimation of uraemic toxins with different removal kinetics: a novel approach based on intradialytic spent dialysate measurements.
Paats J, Adoberg A, Arund J, Dhondt A, Fernström A, Fridolin I, Glorieux G, Gonzalez-Parra E, Holmar J, Leis L, Luman M, Perez-Gomez VM, Pilt K, Sanchez-Ospina D, Segelmark M, Uhlin F, Ortiz A. Clin Kidney J. 2022 Dec 20;16(4):735-744. doi: 10.1093/ckj/sfac273. eCollection 2023 Apr.

Patient participation-18 months of patient and staff perspectives in kidney care: A mixed methods study addressing the effects of facilitating staff person-centredness.
Hurtig C, Årestedt L, Uhlin F, Eldh AC. J Eval Clin Pract. 2024 Jul 18. doi: 10.1111/jep.14099. Online ahead of print.

Grants (last three years)

2024

ALF

500 000 SEK

2023

Ministry of Education and Research

7 000 000 EUR

ALF

500 000 SEK

Njurfonden

500 000 SEK

Familjerna Carl och Albert Molins i Motala minne - blandad fond, Sverige - Annan forskningsfinansiär

70 000 SEK

Hälsofonden, Sverige - Universitet och högskolor

150 000 SEK

2022

Svenska Läkaresällskapets forskarmånader

150 000 + projektanslag 125 000 SEK

2021

Ingrid Asps Stiftelse

1 250 000 SEK

Njurfonden, Sverige - Annan forskningsfinansiär

150 000 SEK

Research leaders

Advisory board

Steering committee

LiU Donation

All employees

Organization