Molecular Ion Channels Physiology

Nervous system cells are located at the treshold that makes them four of rapid nerve impulses.

A high or low threshold can cause epilepsy or pain. We study a new mechanism by which different substances can raise or lower the threshold by opening or closing the voltage activated ion channels.

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Publications

Tracking a complete voltage-sensor cycle with metal-ion bridges

Authors: Ulrike Henrion, Jakob Renhorn, Sara Börjesson, Erin M Nelson, Christine S Schwaiger, Par Bjelkmar, Björn Wallner, Erik Lindahl, Fredrik Elinder

Publ 2012
Type Article in journal
To publication

Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac I-Ks channel

Authors: Sara Liin, Malin Silverå Ejneby, Rene Barro-Soria, Mark Alexander Skarsfeldt, Johan Larsson, Frida Starck Härlin, Teija Parkkari, Bo Hjorth Bentzen, Nicole Schmitt, H. Peter Larsson, Fredrik Elinder

Publ 2015
Type Article in journal
To publication

Resin-acid derivatives as potent electrostatic openers of voltage-gated K channels and suppressors of neuronal excitability

Authors: Nina Ottosson, Xiongyu Wu, Andreas Nolting, Urban Karlsson, Per-Eric Lund, Katinka Ruda, Stefan Svensson, Peter Konradsson, Fredrik Elinder

Publ 2015
Type Article in journal
To publication

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