Fredrik Elinder

Molecular Ion Channels Physiology

Nerve cells are close to the threshold that makes them fire rapid nerve impulses.

A high or low threshold can cause epilepsy or pain. We study a new mechanism by which different substances can raise or lower the threshold by opening or closing the voltage activated ion channels.

Research

Research Areas

Publications

Nina Ottosson, Malin Silverå Ejneby, Xiongyu Wu, Samira Yazdi, Peter Konradsson, Erik Lindahl, Fredrik Elinder (2017)
A drug pocket at the lipid bilayer-potassium channel interface

Science Advances Continue to DOI

Ulrike Henrion, Jakob Renhorn, Sara Börjesson, Erin M Nelson, Christine S Schwaiger, Par Bjelkmar, Björn Wallner, Erik Lindahl, Fredrik Elinder (2012)
Tracking a complete voltage-sensor cycle with metal-ion bridges

Proceedings of the National Academy of Sciences of the United States of America Continue to DOI

Sara Liin, Malin Silverå Ejneby, Rene Barro-Soria, Mark Alexander Skarsfeldt, Johan Larsson, Frida Starck Härlin, Teija Parkkari, Bo Hjorth Bentzen, Nicole Schmitt, H. Peter Larsson, Fredrik Elinder (2015)
Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac I-Ks channel

Proceedings of the National Academy of Sciences of the United States of America Continue to DOI

Co-workers

Organisation

Tags