25 May 2023

Linda Bojmar, a researcher from Linköping University, has played a significant role in a groundbreaking study investigating the effects of cancers in distant organs on liver function.

Person writes with a pen on a test tube.
Linda Bojmar. Photographer: John Karlsson

The study, titled "Tumour extracellular vesicles and particles induce liver metabolic dysfunction" was recently published in the prestigious scientific journal Nature.

Understanding the Impact of Cancer on Liver Function

The study sheds new light on how cancers in distant organs can profoundly impact liver function, providing crucial insights for cancer treatment and management. By analyzing data from both clinical and experimental models, the researchers discovered that distant cancers influence liver function through the release of certain molecules into the bloodstream. These molecules trigger significant changes in liver metabolism and immune responses, which can ultimately affect patient outcomes.

A Remarkable Collaboration

The study is the result of a remarkable collaboration among researchers from Linköping University, Weill Cornell Medicine, and several other renowned institutions. This multidisciplinary approach allowed for a comprehensive investigation into the complex mechanisms underlying the impact of distant cancers on liver function.

Future Implications for Cancer Treatment

The findings from this study hold great promise for the development of new treatment strategies and therapeutic targets for cancer patients. Understanding how distant cancers affect liver function opens doors to innovative approaches in personalized medicine, enhancing the precision and effectiveness of cancer therapies.

More information

Link to press release from Weill Cornell: https://news.weill.cornell.edu/news/2023/05/cancers-in-distant-organs-alter-liver-function
Link to article in Nature: https://www.nature.com/articles/s41586-023-06114-4

More about Linda Bojmar

Latest news from LiU

Theopisti Stylianou-Lambert.

Theopisti Stylianou-Lambert is the next Moa Martinson Professor

Theopisti Stylianou-Lambert is a visual artist, researcher and a professor at the Cyprus University of Technology. Her research and artistic practice focus on museum studies and visual sociology, particular on photography and emerging technologies.

Thomas Keating at a table with a computer in front of him.

Highly radioactive nuclear waste – how to keep it from oblivion

Sweden’s radioactive nuclear waste will be stored in a sealed bedrock repository for 100,000 years. How can we ensure that it is not forgotten? Researchers at Linköping University have come up with a proposal.

Corinna Röver standing on a stair.

Reindeer husbandry in the shadow of war – then and now

Sweden’s NATO membership may entail increased military activity in Sami reindeer herding areas. One way of trying to predict the consequences of this is to look back in history. This is what a new research project at LiU will do.