25 May 2023

Linda Bojmar, a researcher from Linköping University, has played a significant role in a groundbreaking study investigating the effects of cancers in distant organs on liver function.

Person writes with a pen on a test tube.
Linda Bojmar. John Karlsson

The study, titled "Tumour extracellular vesicles and particles induce liver metabolic dysfunction" was recently published in the prestigious scientific journal Nature.

Understanding the Impact of Cancer on Liver Function

The study sheds new light on how cancers in distant organs can profoundly impact liver function, providing crucial insights for cancer treatment and management. By analyzing data from both clinical and experimental models, the researchers discovered that distant cancers influence liver function through the release of certain molecules into the bloodstream. These molecules trigger significant changes in liver metabolism and immune responses, which can ultimately affect patient outcomes.

A Remarkable Collaboration

The study is the result of a remarkable collaboration among researchers from Linköping University, Weill Cornell Medicine, and several other renowned institutions. This multidisciplinary approach allowed for a comprehensive investigation into the complex mechanisms underlying the impact of distant cancers on liver function.

Future Implications for Cancer Treatment

The findings from this study hold great promise for the development of new treatment strategies and therapeutic targets for cancer patients. Understanding how distant cancers affect liver function opens doors to innovative approaches in personalized medicine, enhancing the precision and effectiveness of cancer therapies.

More information

Link to press release from Weill Cornell: https://news.weill.cornell.edu/news/2023/05/cancers-in-distant-organs-alter-liver-function
Link to article in Nature: https://www.nature.com/articles/s41586-023-06114-4

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