Cell and Molecular Biology

Molecular Biology research focus on  how molecules and systems within cells interact. Of special interest is the flow of genetic information from DNA via RNA to protein synthesis, and how these processes are regulated.


The human body contains on average 50 to 75 trillion cells of hundreds of different types, all with a special task. The individual cell possesses properties that define life; it can grow, divide itself, receive and respond to stimuli from its surroundings, and carry out an impressive number of chemical reactions. The function determines how the cell is built and where it is found in the body.

Cell Biology research studies the function of  different cell types, through signalling within the cell, and how they communicate and cooperate with other cells.

The advances in Molecular Biology over the past few years has led to a biological and medical revolution with entirely new methods for analysis and studies of hereditary factors. This has changed our view of what is  life and resulted in a rapid development within biotechnology, biomedicine, and plant breeding. The genetic and cell biology basis for many diseases will be elucidated in the coming years  and the gained  knowledge is  already implemented  in clinical diagnostics and therapies.

Research

Doesn't one sperm suffice?

Doesn´t one sperm suffice

Reproduction is, for its comparative strength and dynamic character, a major sentinel of the health of animals and humans. Basic discoveries in relation to sperm selection and preservation of cell integrity have been central in our research.

Cell signaling in inflammation and cancer.

Cell signaling in intestinal inflammation

All cells in an organism communicate with one another and with their environment through integrated signaling pathways. By exploring the molecular events that shape cellular decision-making, we can predict and control the fate of individual cells.

Molecular physiology of voltage-gated ion channels.

Molecular physiology of voltage-gated ion channels

Voltage-gated ion channels are key players in all biological systems where they generate and modulate for instance the nervous impulse and pacemaker activity in the heart and the brain.

Research centers

Discovery

News

Two men in a laboratory.

Discovery reveals how cells respond to each other

The same message can be interpreted differently by different individuals – also among cells. This is shown in a study by researchers at Linköping University who studied cell communication.

women clasping her hands over chest.

Estrogen possible risk factor in disturbed heart rhythm

The sex hormone estrogen has a negative impact on heartbeat regulation, according to an experimental study from LiU. Estrogen impact seems to interact with hereditary changes causing a heart disease disturbing the heart’s rhythm.

Colm Nestor.

SEK 22 million ERC grant to research on sex-bias in disease

Associate professor Colm Nestor has been awarded a Consolidator Grant from the European Research Council (ERC) of approximately SEK 22 million over the next 5 years. The funding will be used to research sex bias in human disease.