Photo of Jonas Wetterö

Jonas Wetterö

Associate Professor, Docent

Associate Professor (Docent) of Experimental Rheumatology

Inflammatory mediators in rheumatic diseases


The overall aim of the research is to obtain an enhanced understanding of inflammation for the benefit of patients with inflammatory diseases, mainly rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). To accomplish this, we perform experimental studies in acute inflammation and innate immunology to target inflammatory mediators.
Key areas include the biological roles and synthesis regulation of acute phase proteins (including complement), autoantibodies, immune complexes, leukocyte respiratory burst reactions/frustrated phagocytosis, and platelets in inflammation.
In addition I have a long standing interest in biointerphases and biosensors.


I am the Program Director of the international "Experimental & Industrial Biomedicine" Bachelor’s Programme, Director of Studies for a handful of courses for civil engineering students (Engineering Biology and Chemical Biology), and examiner for courses in, for example, Immunology and Cell Biology, and for Degree Projects.



Jesper Karlsson, Jonas Wetterö, Lawrence A. Potempa, Rafael Fernandez-Botran, Yasmine ONeill, Lina Wirestam, Fariborz Mobarrez, Christopher Sjöwall (2023) Extracellular vesicles opsonized by monomeric C-reactive protein (CRP) are accessible as autoantigens in patients with systemic lupus erythematosus and associate with autoantibodies against CRP Journal of Autoimmunity, Vol. 139, Article 103073 Continue to DOI
Lina Wirestam, Frida Jönsson, Helena Enocsson, Christina Svensson, Maria Weiner, Jonas Wetterö, Helene Zachrisson, Per Eriksson, Christopher Sjöwall (2023) Limited Association between Antibodies to Oxidized Low-Density Lipoprotein and Vascular Affection in Patients with Established Systemic Lupus Erythematosus International Journal of Molecular Sciences, Vol. 24, Article 8987 Continue to DOI
Per Lewander, Lina Wirestam, Charlotte Dahle, Jonas Wetterö, Christopher Sjöwall (2023) Serum levels of soluble urokinase plasminogen activator receptor in juvenile idiopathic arthritis: a single-center Swedish case-control study Pediatric Rheumatology, Vol. 21, Article 49 Continue to DOI
Cecilia Svanberg, Helena Enocsson, Melissa Govender, Klara Martinsson, Lawrence A. Potempa, Ibraheem M. Rajab, Rafael Fernandez-Botran, Jonas Wetterö, Marie Larsson, Christopher Sjöwall (2023) Conformational state of C-reactive protein is critical for reducing immune complex-triggered type I interferon response: Implications for pathogenic mechanisms in autoimmune diseases imprinted by type I interferon gene dysregulation Journal of Autoimmunity, Vol. 135, Article 102998 Continue to DOI


Muna Atallah Saleh, Michele Compagno, Sofia Pihl, Helena Strevens, Barbro Persson, Jonas Wetterö, Bo Nilsson, Christopher Sjöwall (2022) Variation of Complement Protein Levels in Maternal Plasma and Umbilical Cord Blood during Normal Pregnancy: An Observational Study Journal of Clinical Medicine, Vol. 11, Article 3611 Continue to DOI


Astma och allergi Foto: istock

Autoimmunity and allergy

Autoimmune diseases and allergies are, as a rule, chronic conditions, which can cause significant impairment of function and can sometimes be life-threatening.

Virus. Foto: Istock

Infection and Inflammation

Research in the field of inflammation stretches over a broad area. Important areas are vaccines and human genetic factors in virus infections, resistance to antibiotics, tick-borne infections, and the role of inflammation in cardiovascular disease.