Jonas Wetterö

Strategies to combat the allergy epidemic: Can we predict and prevent childhood allergies?

Childhood immune maturation and allergy development: Epigenetic regulation by maternal immunity and microbial exposure during pregnancy.

Ingrid Asp Psoriasis Research Center

Our research program has been made possible by a generous donation from the Ingrid Asp Foundation. Our ultimate goal is to obtain an improved understanding of the pathogenesis of psoriasis and to find new modalities for its therapy.

Experimental and Clinical Studies of Psoriasis

We are studying the pathogenesis of the disease in experimental systems using broad cell biological techniques. Special interest is devoted to psoriasin which is a small protein...

Ingrid Asp Kidney Research Center

The Nestor Lab

Our research aims to understand the function of DNA methylation in the biology of human CD4+ T-cells, and use this knowledge to dissect its role in disease.

Autism and ADHD are linked to disturbed gut flora very early in life

Disturbed gut flora during the first years of life is associated with diagnoses such as autism and ADHD later in life. This is according to a study led by researchers at the University of Florida and LiU and published in the journal Cell.

Severe MS predicted using machine learning

A combination of only 11 proteins can predict long-term disability outcomes in multiple sclerosis (MS) for different individuals. The proteins could be used to tailor treatments to the individual based on the expected severity of the disease.

Gut flora disrupted many years before onset of child rheumatism

A study by researchers from LiU and the University of Florida is the first study to point to the role of early life gut flora in developing child rheumatism, the cause of which is not yet known.

Researching gut bacteria as protection against disease

Did the bacteria in your guts when you were a baby impact your risk of future disease? We have talked to researcher studying whether diseases such as type 1 diabetes and allergy could be prevented by promoting the right bacteria early in life.

C-reactive protein reduces immune response in inflammatory disease

The biological function of the C-reactive protein, CRP, has long been unknown. Researchers now show that this protein has a beneficial function in SLE, an inflammatory disease. But this is true only for one of CRP’s two forms, according to the study.

Research Focus Dermatology

The ultimate goal of the research is to increase the understanding of the underlying mechanisms of skin diseases, in order to facilitate the development of more specific treatments and clinical care.

Digital twins an aid to give individual patients the right treatment at the right time

An international team of researchers have developed advanced computer models, or “digital twins”, of diseases, with the goal of improving diagnosis and treatment. They used one such model to identify the most important disease protein in hay fever.

SEK 10 million for research in children's medicine

The Joanna Cocozza Foundation has announced the recipients of research grants for 2020. Funding has been awarded in the form of establishment and consolidation grants, support for visiting researchers, and a further seven project grants.

Clinical and experimental rheumatology

A long-term ambition is to contribute to increased understanding of underlying mechanisms for the disease onset, progress and perceived quality of life in systemic inflammatory diseases, especially with regard to systemic lupus erythematosus (SLE)

The impact of mercury, silver, gold and drugs on the immune system

We have studied adverse effects on the immune system by exposure in vitro and in vivo using both animal models and humans. This has enabled us to establish the threshold dose for effect of different modes of exposure to mercury, silver, and gold.

A new focus on children's allergies

More and more children have allergies. LiU researchers are working to combat the allergy epidemic – using bacteria from the mothers.

New warning system discovered in the immune defence

Researchers at LiU have discovered a previously unknown warning system that contributes to the body’s immune system. Mitochondria in the white blood cells secrete a web of DNA fibres that raises the alarm.

Allergy research from LiU in Japanese TV documentary

A Japanese tv team spent three days at LiU, filming parts of a series about the human body. Their focus: Maria Jenmalm’s research why children born by Caesarean section develop a poorer gut flora and are more often affected by allergy.

Intestinal diversity protects against asthma

Children who develop asthma or allergies have an altered immune response to intestinal bacteria in the mucous membranes even as infants. This has been shown by a new study at Linköping University in Sweden.

Predicting the severity of multiple sclerosis

Cells in the immune system of patients with multiple sclerosis behave differently from those of healthy individuals. LiU researchers have exploited this difference to develop a method that can predict disease activity in multiple sclerosis.

Forum Scientium Graduate School

Graduate school Forum Scientium, a bridge between medicine, natural sciences and engineering, stimulates creativity and a common use of ideas, knowledge, and equipment.

Autoimmunity and allergy

Autoimmune diseases and allergies are, as a rule, chronic conditions, which can cause significant impairment of function and can sometimes be life-threatening.

Translational bioinformatics

Many currently used drugs are ineffective for treating complex diseases. However, modern biology today generates enormous amounts of inexpensive, accurate, high-throughput data (‘omics), at several molecular levels.§

Reproduction and Neuro Immunology

The general purpose of our research is to reveal mechanisms of immune tolerance in pregnancy and how failure of tolerance mechanisms can lead to pregnancy complications.