Fotografi av Shadi Jafari

Shadi Jafari

Förste forskningsingenjör

Presentation

At The Nestor Lab - Linköping University, I investigate why females often fight infections better than males yet are more susceptible to autoimmune diseases, focusing on how the X chromosome and its epigenetic regulation shape immune differences.

With a background in medicine from Tehran and a PhD in Neurobiology from Linköping University, my research has explored how genes and chromatin structure govern neuronal identity and development in Drosophila and other insects.

Now a Senior Research Engineer at Linköping University, I lead an ERC-funded project on X-chromosome inactivation and its impact on sex differences in immunity. My long-term goal is to uncover how chromatin and X-linked gene activity influence immunity, neurodevelopment, and aging.

Publikationer

2021

Shadi Jafari, Johan Henriksson, Hua Yan, Mattias Alenius (2021) Stress and odorant receptor feedback during a critical period after hatching regulates olfactory sensory neuron differentiation in Drosophila PLoS biology, Vol. 19, Artikel e3001101 (Artikel i tidskrift) Vidare till DOI

2019

Alejandra Gonzalez Bosca, Shadi Jafari, Alberto Zenere, Mattias Alenius, Claudio Altafini (2019) Thermodynamic model of gene regulation for the Or59b olfactory receptor in Drosophila PloS Computational Biology, Vol. 15, Artikel e1006709 (Artikel i tidskrift) Vidare till DOI

2016

Gonzalo Manuel Sanchez, Liza Alkhori Franzén, Eduardo Hatano, Sebastian Schultz, Anujaianthi Kuzhandaivel, Shadi Jafari, Björn Granseth, Mattias Alenius (2016) Hedgehog Signaling Regulates the Ciliary Transport of Odorant Receptors in Drosophila Cell Reports, Vol. 14, s. 464-470 (Artikel i tidskrift) Vidare till DOI

Forskargrupp

Organisation