Urban Karlsson

Förste forskningsingenjör

Publikationer

2026

Pei Xin Boon, Amaia Jauregi-Miguel, Sümeyye Süheda Yasarbas, Serena Pozzi, Urban Karlsson, Ammar Husami, Charmaine Ko, Amelle Shillington, Antonios Pantazis (2026)

Differential negative dominance by KCNA2 variants associated with global developmental delay suggests KCNA2 haploinsufficiency in humans Journal of Physiology, Vol. 604, s. 3413-3430 (Artikel i tidskrift)

https://dx.doi.org/10.1113/jp290728

Pei Xin Boon, Amaia Jauregi Miguel, Sümeyye Süheda Yasarbas, Serena Pozzi, Urban Karlsson, Ammar Husami, Charmaine Ko, Amelle Shillington, Antonios Pantazis (2026)

Differential negative dominance by KCNA2 variants associated with global developmental delay suggests KCNA2 haploinsufficiency in humans Journal of Physiology (Artikel i tidskrift)

https://dx.doi.org/10.1113/JP290728

2022

Serge Moudio, Fredrik Rodin, Nazira Albargothy, Urban Karlsson, Juan Reyes, Martin Hallbeck (2022)

Exposure of alpha-Synuclein Aggregates to Organotypic Slice Cultures Recapitulates Key Molecular Features of Parkinsons Disease Frontiers in Neurology, Vol. 13, Artikel 826102 (Artikel i tidskrift)

https://dx.doi.org/10.3389/fneur.2022.826102

2021

Nina Ottosson, Malin Silverå Ejneby, Xiongyu Wu, Argel Estrada Mondragón, Michelle Nilsson, Urban Karlsson, Melanie Schupp, Salome Rognant, Thomas Andrew Jepps, Peter Konradsson, Fredrik Elinder (2021)

Synthetic resin acid derivatives selectively open the hK(V)7.2/7.3 channel and prevent epileptic seizures Epilepsia, Vol. 62, s. 1744-1758 (Artikel i tidskrift)

https://dx.doi.org/10.1111/epi.16932

2020

Johan Larsson, Urban Karlsson, Xiongyu Wu, Sara Liin (2020)

Combining endocannabinoids with retigabine for enhanced M-channel effect and improved KV7 subtype selectivity The Journal of General Physiology, Vol. 152, Artikel e202012576 (Artikel i tidskrift)

https://dx.doi.org/10.1085/jgp.202012576

Min forskning

Molecular physiology of voltage-gated ion channels.

Spänningsaktiverade jonkanalers molekylära fysiologi

Vi drivs av elektricitet. Varje tanke, varje hjärtslag, varje kroppsrörelse styrs av blixtsnabba elektriska impulser. Dessa impulser beror på att kanaler i cellernas membran öppnar sig och släpper igenom elektriskt laddade joner.