Organic Bioelectronics

Jonpump version 2. Kretsar och droppar på plastlaminat.
An organic electronic ion pump (OEIP). The device uses electrophoretic transport through thin polymer films to deliver ions, neurotransmitters, plant hormones, and other small charged molecules into living tissue.

Communicating across the biology-technology divide.

Principal investigator: Daniel Simon

jonpump 2015 Animals, plants, and all biological systems communicate in a language of ions and molecules. Modern technology, on the other hand, relies on a language of electrons. With organic electronic materials’ unique properties, we develop “bilingual” tools to bridge this gap.

Organic electronic materials possess a combination of both electronic and ionic/molecular conductivity. They have thus emerged as excellent tools for developing hybrid technologies that effectively interface biological systems with modern electronic technology such as computers and mobile phones – thus the field of organic bioelectronics. 

In the Organic Bioelectronics group at the Laboratory of Organic Electronics, we investigate this transduction between electronic signals and ionic/molecular signals with self-organising in vivo electrode materials, “iontronic” chemical delivery and circuitry, bacteria-electronic interfaces, biosensors, biomimetic systems, and many other areas.  

We aim to elucidate fundamental processes in biochemistry and physiology, as well as develop tools for next-generation therapies, human-machine interfacing, and blurring the border between living and technological systems.

Body illustration above: Organic bioelectronics for pain therapy in the spinal cord. The ion pump delivers therapeutic neurotransmitters precisely at the location of pain signaling.

Organic Bioelectronics research leaders

Major projects

News about Organic Bioelectronics

Translucent droplet on an electronic circiut.

Electrodes grown in the brain

The boundaries between biology and technology are becoming blurred. Researchers at Linköping, Lund, and Gothenburg universities in Sweden have successfully grown electrodes in living tissue using the body’s molecules as triggers.

Two droplets, one yellow and one clear, on circuits.

Accurate drug dosages with proton traps

Researchers at LiU have developed a proton trap that makes organic electronic ion pumps more precise when delivering drugs. In the long term, the ion pumps may help patients with symptoms of neurological diseases.

Johannes Gladisch

An electronic signal expands the material by a factor of 100

Researchers at the Laboratory of Organic Electronics have discovered a material that can both increase and reduce its volume when exposed to a weak electrical pulse. In a filter, the researchers can control the size of particles that pass through.

Organic Bioelectronics group members

Publications in Organic Bioelectronics


Maciej Gryszel, Donghak Byun, Bernhard Burtscher, Tobias Abrahamsson, Jan Brodsky, Daniel T Simon, Magnus Berggren, Eric Daniel Glowacki, Xenofon Strakosas, Mary Donahue (2024) Vertical Organic Electrochemical Transistor Platforms for Efficient Electropolymerization of Thiophene Based Oligomers Journal of Materials Chemistry C Continue to DOI


Chiara Diacci, Bernhard Burtscher, Marcello Berto, Tero-Petri Ruoko, Samuel Lienemann, Pierpaolo Greco, Magnus Berggren, Marco Borsari, Daniel Simon, Carlo A. Bortolotti, Fabio Biscarini (2023) Organic Electrochemical Transistor Aptasensor for Interleukin-6 Detection ACS Applied Materials and Interfaces Continue to DOI
Matteo Massetti, Silan Zhang, Harikesh Padinhare, Bernhard Burtscher, Chiara Diacci, Daniel Simon, Xianjie Liu, Mats Fahlman, Deyu Tu, Magnus Berggren, Simone Fabiano (2023) Fully 3D-printed organic electrochemical transistors NPJ FLEXIBLE ELECTRONICS, Vol. 7, Article 11 Continue to DOI
Xenofon Strakosas, Hanne Biesmans, Tobias Abrahamsson, Karin Hellman, Malin Silverå Ejneby, Mary Donahue, Peter Ekstrom, Fredrik Ek, Marios Savvakis, Martin Hjort, David Bliman, Mathieu Linares, Caroline Lindholm, Eleni Stavrinidou, Jennifer Gerasimov, Daniel Simon, Roger Olsson, Magnus Berggren (2023) Metabolite-induced in vivo fabrication of substrate-free organic bioelectronics Science, Vol. 379, p. 795-802 Continue to DOI
Dennis Cherian, Arghyamalya Roy, Alex Bersellini Farinotti, Tobias Abrahamsson, Theresia Arbring Sjöström, Klas Tybrandt, David Nilsson, Magnus Berggren, Camilla I. Svensson, David Poxson, Daniel Simon (2023) Flexible Organic Electronic Ion Pump Fabricated Using Inkjet Printing and Microfabrication for Precision In Vitro Delivery of Bupivacaine Advanced Healthcare Materials, Vol. 12, Article 2300550 Continue to DOI
Iwona Bernacka Wojcik, Loic Talide, Ilaria Abdel Aziz, Jan Simura, Vasileios Oikonomou, Stefano Rossi, Mohsen Mohammadi, Abdul Manan Manan Dar, Maria S Seitanidou, Magnus Berggren, Daniel Simon, Klas Tybrandt, Magnus Jonsson, Karin Ljung, Totte Niittyla, Eleni Stavrinidou (2023) Flexible Organic Electronic Ion Pump for Flow-Free Phytohormone Delivery into Vasculature of Intact Plants Advanced Science, Vol. 10, Article 2206409 Continue to DOI
Arghyamalya Roy, Alex Bersellini Farinotti, Theresia Arbring Sjöström, Tobias Abrahamsson, Dennis Cherian, Michal Karaday, Klas Tybrandt, David Nilsson, Magnus Berggren, David Poxson, Camilla I. Svensson, Daniel Simon (2023) Electrophoretic Delivery of Clinically Approved Anesthetic Drug for Chronic Pain Therapy Advanced Therapeutics, Vol. 6, Article 2300083 Continue to DOI

Join us!

More research within Laboratory of Organic Electronics