Fotografi av Francisca Lottersberger

Francisca Lottersberger


Syftet med min forskning är att förstå hur integriteten i genomet upprätthålls, med särskild tonvikt på kromatinmobilitetens roll.

Kromatinmobilitet och genomintegritet

För mer information om min forskning, se den engelska sidan (ovan till höger).

Medarbetare i min forskargrupp




  1. Lottersberger F., Karssemeijer R.A., Dimitrova N. and de Lange T. (2015). 53BP1 and the LINC complex promote microtubule-dependent DSB mobility and DNA repair. Cell 2015 Nov 5;163(4):880-93. Featured Article
  2. Zimmermann M., Lottersberger F., Buonomo S.B., Sfeir A. and de Lange T. (2013). 53BP1 regulates DSB repair using Rif1 to control 5' end resection. Science 2013 Feb 8;339(6120):700-4.
  3. Lottersberger F.*, Bothmer A.*, Robbiani D.F., Nussenzweig M.C. and de Lange T. (2013). Role of 53BP1 oligomerization in regulating double-strand break repair. Proc. Natl Acad Sci U S A Feb 5;110(6):2146-51. 
    * equal contribution.
  4. Lottersberger F., Panza A., Lucchini G. and Loghese MP. (2007). Functional and physical interactions between yeast 14-3-3, acetyltransferase and deacetylase proteins in response to DNA replication stress” Mol. Cell. Biol. May;27(9):3266-81.
  5. Lottersberger F., Panza A., Piatti S., Lucchini G. and Loghese MP. (2006). The Saccharomyces cerevisiae 14-3-3 Proteins Are Required for the G1/S Transition, Actin Cytoskeleton Organization and Cell Wall Integrity” Genetics Jun;173(2):661-75.
  6. Clerici M., Baldo V., Mantiero D., Lottersberger F., Lucchini G. and Longhese MP. (2004). A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1. Mol Cell Biol. Dec; 24(23):10126-44. 
  7. Lottersberger F., Rubert F., Baldo V., Lucchini G. and Loghese MP. (2003). Functions of Saccharomyces cerevisiae 14-3-3 proteins in response to DNA damage and to DNA replication stress. Genetics Dec;165(4):1717-32.

Om mig


  • Master degree University of Milano-Bicocca, Italy - 2002
  • Ph.D. University of Milano-Bicocca, Italy – 2006
  • Post-doc University of Milano-Bicocca, Italy - 2006
  • Post-doc The Rockefeller University, NY, USA - 2017