Research at the Faculty of Medicine and Health Sciences

Journeys - Safe and Informed Journeys through Barnahus

The overall objective of the JOURNEYS project is to contribute to improved access to child-friendly justice, protection and recovery for child victims and their families.

Disaster Medicine

Knowledge within the field of disaster medicine forms the basis of the preparedness of the health care system for disastrous events.

Wallenberg Centre for Molecular Medicine at LiU

WCMM at LiU focuses on the medicine-technology interface, and build upon our existing strengths in research within medical technology, materials science and bioengineering.

Bojmar Lab

Cancer is a systemic disease. Our research focuses on understanding crosstalk between different organs in the human body, and how this affects cancer progression. We focus mainly on gastrointestinal cancers and their common hepatic metastasis.

Research Programme DEM(H)CARE

An interdisciplinary research programme aiming to improve coordination between home care, municipal health care, and primary care for people with dementia living at home.

SciLifeLab Linköping

SciLifeLab Linköping is both a local and a national research infrastructure, with unique technologies and expert competence accessible for academic and industrial researcher in the field of life sciences, health and data-driven life science.

Artificial Intelligence in Mammography Screening (AIM)

Artificial Intelligence in Mammography Screening - AIM is a research program with a particular focus on clinical utility, efficiency, and implementation aspects.

e-Health

e-Health is one of five areas of strength at Linköping University and Region Östergötland. The areas' mission is to conduct internationally outstanding research and to create an inclusive research environment with high scientific level.

WellTECH@age

Ingrid Asp Kidney Research Center

Tick-borne infections

We conduct translational, patient-centered research on tick-borne infections and COVID-19. Collaborative projects form the foundation of the translational research being carried out.

ABOGRAFT

The ABOGRAFT study is a multi-center international study into the effects of providing local antibiotics to prevent joint infection in patients who undergo hip replacement surgery using bone graft.

Neurodegeneration

We perform clinical and experimental studies to investigate the role of autophagy in the development of peripheral neuropathy in conditions such as diabetes or physical trauma.

Cell migration in health and disease

Directional cell motility follows us from creation to death and is a vital part of life. Our main interest in this regard is how water flux via AQP contribute to the process of membrane protrusion necessary for directional whole cell translocation.

Genetics and Toxicology in Cancer Chemotherapy and Forensic Sciences

The aim of our research is to identify, validate and implement genetic markers or other biomarkers to predict drug metabolism or drug effects.

Effect of non-invasive lung fluId monitoring for heart failure management in Primary Care - LILAC-HF

Heart failure is a growing health concern, particularly among the elderly. Heart failure patients often experience repeated hospitalizations. It is currently the most common cause of hospital admissions for people over the age of 65.

Cultural competence for Healthcare professionals

The instrument can be used both in research as a data collection instrument and as a clinically applied instrument in various activities. Several research projects linked to the instrument are currently underway.

The LVAD Self-Care Behaviour Scale

The Left Ventricular Assist Device Self-care Behaviour Scale.

Pantazis Laboratory of Cellular Excitability – PaLaCE

In the Pantazis Laboratory of Cellular Excitability - PaLaCE, we employ cutting-edge experimental and computational approaches to understand how the intricate structure of ion channels relates to their function.

Center for Social and Affective Neuroscience - CSAN

Center for Social and Affective Neuroscience (CSAN) integrates knowledge and methodology from different areas of basic and clinical neuroscience.

The study group of ectopic fat storage

Vi studerar hur fettinlagring i olika organ, så som lever, muskel och hjärta, ökar risken för sjukdomsutveckling. Förhoppningen är att kartläggning kommer att hjälpa oss att identifiera de individer som löper högst risk att utveckla sjukdom.

How to solve murders using postmortem metabolomics and artificial intelligence

Successful efforts from this research environment will be implemented into routine case work and will aid police work in providing investigative leads and new tools to expand objective forensic evidence.

The care program: Better Back

The care program Betterback☺︎ is intended to support diagnostic and treatment intervention processes for more effective primary care for patients with a new onset of low back pain, with or without radiculopathy.

The international Center for Self-Care Research

Shoulder problems – assessment, treatment and outcome measures

The overarching aim is to improve diagnostics, treatment and evaluation of patients with shoulder problems both within primary care rehabilitation and in the orthopedic setting.

Teleyoga - when east meets west

We investigate whether medical yoga sent remotely can improve people’s health. Heart disease patients and former intensive care patients are included in the study.

The Research Group for Frail, Seriously Ill Patients

Neuroretreat 2025

Center for Systems Neurobiology at Linköping University is organizing a retreat on 15th to 16th of May, 2025.

REAGERA – Responding to Elder Abuse in Geriatric Care

In Swedish studies about 15% of older women and men report that they have been subjected to emotional, physical, sexual or financial abuse or neglect.

Regional Infectious Disease Epidemiology and Simulations - RIDES

Our research concerns epidemiological data and information processing in connection with infectious disease outbreaks at local and regional level.

Collaboration of health and care services for people with dementia

Planning out: coordination of health and social care services for older people with dementia when discharged from inpatient care

Digital support programme for informal carers of people with heart failure

The ongoing research project aims to evaluate the effects of a support programme for informal carers of persons with heart failure. The programme is brought via the interactive web platform Support and Treatment on the national health portal 1177.se.

The Heart-exergame study

In general, everybody is recommended to be physically active for at least 150 minutes a week to improve health. Physical activity helps us to participate in daily life activities, stay independent for a longer time and have a good quality of life.

Suicidal care

Pain and nutrition

Interest in the role of healthy eating and nutrition-related health in pain management is increasing in both the research and clinical space.

Molecular Regulation of Epigenetic Inheritance of Metabolic Disease

New evidence suggests that metabolic memories, set by the parents, can affect eating behavior and obesity in future generations.

Tumor Immunology and Immunotherapy

The aims of our research are to uncover the cellular and molecular mechanisms that predispose to systemic and long-term anti-tumor immunity and the mechanisms that drive resistance to immunotherapy.

Experiencing the Self through Touch

Through functional magnetic resonance imaging (fMRI) this project gathers information about the boundaries between the self and others and compares the outcome of the reactions of neurotypical volunteers with participants with a psychiatric disorder

Auditory neuroscience group

To study the function of these stereocilia, the research group has developed a new type of confocal microscope that makes it possible to directly observe sound-evoked motion.

Sport without injury programme - SWIPE

Our research includes study of injury occurrence and risk factors in sports. We also evaluate the efficacy of injury preventive measures, and their effectiveness, including applicability in different sports and sporting populations.

The Cantù Lab - Genome Regulation in Development and Disease

The Cantù Lab at LiU is focused on one important goal: to discover the mechanisms of genome regulation that drive cell differentiation and specialization during embryonic development.

The Zetterqvist Lab

Our research group addresses nonsuicidal self-injury (NSSI) which is a significant mental health issue in adolescents and linked with impairments in emotion regulation. We are dedicated to developing novel approaches for preventing and treating NSSI.

Occupational therapy research

Occupational therapy research aims to reduce obstacles to functioning in society and increase individuals’ opportunities for participating actively in their everyday situations irrespective of their disabilities.

MHED-Lab health behaviour and behaviour change interventions

The Research Group in Medical Education

The object of Medical Education research is the relational and continuous nature of pedagogical processes in professional health care education and in health care itself, and the knowledge-bases decisive for professional formation and intervention.

The Normative Study of Driving Ability in Old Swedes - NorDAS

In this study, healthy active drivers that are 75 years of age and older will have an opportunity to contribute to improved evaluations of driving ability.

SCAPIS Micro

Changes in the smallest vessels in the body, the microcirculation, affect oxygen and nutrient delivery to the cells. A new optical technique gives the opportunity to find relations between dysfunctional microcirculation and cardiovascular disease

Studies on chronic lymphocytic leukemia

We reported a novel finding on the highly restricted and biased specificities of CLL Abs some years ago, showing limited target structures for the CLL Abs, which were exposed on oxidized-LDL, apoptotic cells...

Selective vulnerability to neurodegeneration

Neurodegenerative diseases cause stereotypical signs based on the specific brain region that is targeted. We try to understand how unaffected regions resist disease with the hope that these secrets can be transferred to vulnerable brain regions.

Cardiac Rhythm

Ion channels are critical for heart rhythm. They generate and regulate the electric activity that underlies each heart beat.

Research on reproductive endocrinology

Age related decreases in sex steroid production often lead to a number of symptoms and metabolic changes. The research is focusing on these issues with special attention being given to changes in hypothalamic temperature regulation.

The Endoplasmic Reticulum stress response and its role in disease

ER stress is a key molecular link in the pathology of numerus human diseases including metabolic syndrome, and protein misfolding diseases. In my research, I try to understand how this is possible and find new approaches for diagnosis/treatment.

Endocrine tumors

Molecular genetic analysis of endocrine tumors (thyroid, parathyroid, adrenal, neuroendocrine): pathogenesis and development of metastases.

CIRCA – a support for social interaction

CIRCA is a webpage developed to support social interaction for people who find it challenging to partake in conversational activities, for example older aduls who experience memory problems, and their next of kin.

The Nagi Lab

Pain in the ultrafast lane. We are interested in better understanding the peripheral nervous system’s role in acute and persistent pain using microneurography.

Cell signaling in intestinal inflammation

All cells in an organism communicate with one another and with their environment through integrated signaling pathways. By exploring the molecular events that shape cellular decision-making, we can predict and control the fate of individual cells.

Circulation and metabolism - CircM

CircM is a strategic research network for researchers at Linköping University and Region Östergötland within the research field circulation and cardio-metabolic risk factors.

Doesn´t one sperm suffice

Reproduction is, for its comparative strength and dynamic character, a major sentinel of the health of animals and humans. Basic discoveries in relation to sperm selection and preservation of cell integrity have been central in our research.

The Nestor Lab

Our research aims to understand the function of DNA methylation in the biology of human CD4+ T-cells, and use this knowledge to dissect its role in disease.

The impact of mercury, silver, gold and drugs on the immune system

We have studied adverse effects on the immune system by exposure in vitro and in vivo using both animal models and humans. This has enabled us to establish the threshold dose for effect of different modes of exposure to mercury, silver, and gold.

Bone, mineralization and vascular calcification

Mineralization occurs normally in bone but has, nevertheless, much in common with the pathological process of vascular calcification, which inevitably leads to increased morbidity and mortality.

Molecular physiology of voltage-gated ion channels

Voltage-gated ion channels are key players in all biological systems where they generate and modulate for instance the nervous impulse and pacemaker activity in the heart and the brain.

Cornea Research

Our research team focuses on understanding the origins of blinding diseases of the cornea, evaluating new pharmacologic, surgical, and regenerative therapies to treat corneal disease.

Revealing the secrets of the lysosome

The aim of our research is to elucidate how lysosomal functions are regulated in normal cells and how they are affected in different pathological conditions.

Stopping the propagation of neurodegenerative diseases like Alzheimer’s and Parkinson’s

Neurodegenerative disease like Alzheimer's and Parkinson’s are progressive disease that causes great suffering for the victims and relatives, in addition it cause large economic costs for society.

Strategies to combat the allergy epidemic: Can we predict and prevent childhood allergies?

Childhood immune maturation and allergy development: Epigenetic regulation by maternal immunity and microbial exposure during pregnancy.

Experimental and Clinical Studies of Psoriasis

We are studying the pathogenesis of the disease in experimental systems using broad cell biological techniques. Special interest is devoted to psoriasin which is a small protein...

Ingrid Asp Psoriasis Research Center

Our research program has been made possible by a generous donation from the Ingrid Asp Foundation. Our ultimate goal is to obtain an improved understanding of the pathogenesis of psoriasis and to find new modalities for its therapy.

A gift for life?

In 2012 the world’s first systematic attempts of uterus transplantation were conducted at Sahlgrenska University Hospital, Sweden. This unique project explored the sociocultural dimensions of the attempts by studying involved actors’ perspectives.

A Path to Prevention of Elder Abuse in Long-term care, APPEAL

The past year prevalence of elder abuse among community dwelling older adults have been reported to be about 10-15% in both Swedish and international studies.

Young Survivor Unit - YoSU

Our research aims to better understand the development of children who have been seriously ill early in life. Furthermore, to develop and study interventions that, in the long term, increase the children's functioning in everyday life.

Center for Advanced Research in Emergency Response - CARER

A collaboration between LiU and the Swedish Civil Contingencies Agency which aims to consolidate and strengthen LiU's research in risk, response and rescue area.

Computational Cardio-Oncology

Many pediatric cancer care survivors develop serious cardiovascular complications later in life. The emerging field of computational cardio-oncology leverages advanced data methods to better predict and prevent these complications.

Research Group for Child and Family Centred Care

Our vision is to promote, create, translate, and implement innovative research of high quality which can make a difference for children and young people with various conditions.

The McIntyre Lab

Holding a mug, feeling the ground as you walk, petting your furry friend, or hugging your child, all of these touch sensations start with deformation of the skin that the nervous system must process to serve physiological, emotional and social goals.

The Böhme Lab

We investigate how the experience of “self” is generated by the brain and body – and what happens if self-other-distinction is altered in psychiatric conditions or through experimental interventions.

Swedish-speaking children with developmental language disorder in comparison with second language learners

The focus of this project is language processing in children with Developmental Language Disorder (DLD) and bilingual children learning Swedish as their second language (L2). They are similarly challenged by Swedish grammar.

Precursors of Intentional Communication Skills in Children

The project aims to create a checklist for parents, identify early communicative behaviors in young children up to one year of age, and examine their connection to later linguistic and communicative abilities.

Internet-delivered cognitive behavioural therapy for patients with non-cardiac chest pain (IKSIT)

The IKSIT research study focuses on patients who experience anxiety and worry over recurrent non-cardiac chest pain. Patients in this group risk falling between two stools, but cognitive behavioural therapy over the internet may be a solution.

Wallenberg Center for Molecular Medicine Symposium

WCMM at LiU focuses on the medicine-technology interface and build upon our existing strengths in research within molecular medicine, medical technology and bioengineering.

Citizenship and Dementia: International Research Network

The international network “Citizenship and Dementia: International Research Network“ are aimed at stimulating and contributing international research on living with dementia from a citizenship perspective.

EPSOMiP

EPSONIP explores the link between fatty liver, epicardial fat and cardiovascular disease in type 2 diabetes.

Health examinations of children in out-of-home care

Research has consistently shown, both nationally and internationally, that children and young people placed in community care face a higher risk of poor health outcomes.

The Igelström lab

Everyday sensory stimuli often feel overwhelming for autistic people, causing stress and exhaustion. We study brain processes related to sensory problems in autism and other neurodevelopmental conditions.

SWEDEwork – Sustainable work and everyday life

The research group SWEDEwork aims to investigate the individual's prerequisites for a sustainable working life, and to design person-centred interventions in medical and vocational rehabilitation.

N-forte trial

The aim of the N-forte trial is to explore how breast milk composition influences the development of NEC, sepsis and neurological impairment in extremely preterm infants in order to improve future treatments in this patient group.

Epistemologi och post-Covid

The pandemic has impacted us all, but some more than others. For those who are suffering from post-Covid, the lingering impact is particularly tangible. Interdisciplinary research is needed to understand this new health challenge.

An international research study on interprofessional health professions education, ALLin4IPE

In this international research project, we study interprofessional education (IPE) with a special focus on clinical  placements in different health care clinical practices.

Pragmatic Research in Orthopedics - PRIO

Pragmatic Research in Orthopedics is a research group that aim to optimize the quality of care within the field of orthopedic surgery. We have a strong focus on the orthopedic interventions aimed at the lower extremities.

Swedish National Centre for Priorities in Health

The Swedish National Centre for Priorities in Health works with priority setting within health and social care. We conduct and support research on priority setting, and offer support to a broad range of stakeholders regarding priority setting issues.

The Olausson Lab

Human touch is a powerful way of evoking emotions. What is the functional significance of the system for ultrafast nociceptors that we recently discovered? How does the nervous system distinguish social and self-touch? Our lab is looking for answers.

Young and Participating - YoPa

The research includes children and young people with activity limitations in their everyday lives. This can be due to intellectual disabilities, ADHD, mobility impairments, or no specific diagnosis but with need of special support in school.

Experimental Orthopedics

The purpose of this research is to ensure and accelerate the healing of injured bones and tendons.The project involves clinical research that builds on our previous experimental work, mainly regarding PTH and bisphosphonates.

Viral vaccines focused on influenza and HIV

Our research will provide new knowledge about how effective vaccination can be done with a focus on viral infections. Why and how vaccines work is an exciting research area in which we operate.

It’s in your DNA - your body’s experiences become imprinted as methylation signatures!

Our research explores how infections like COVID-19 and tuberculosis alter DNA through epigenetic changes. Tuberculosis exposure leaves marks in immune and other cells. COVID-19 also rewires immune cell DNA, offering diagnostic insights.

The Engblom Lab

At the Engblom Lab, we investigate the mechanisms and circuits underpinning the aversive affective states and the depressive symptoms accompanying inflammatory diseases and major depression.

The Morrison Lab

The Morrison Lab: Embodied Brain Lab investigates emotional and social aspects of both touch and pain, and how these influence - and are influenced by - behavior.

Leukemia and blood stem cells

Regulation of survival and differentiation of hematopoietic stem cells and leukemia-initiating cells.

Individualised diagnosis and treatment of tuberculosis

Our general aim is to individualise and thereby optimize management of clinical TB by new methods and strategies. The research group consists of specialists in tuberculosis from different professions.

PAINOMICS® Research Group

The aim of the research at Painomics laboratory is to investigate mechanistic markers of nociception and severity of pain, in peripheral and central level in subjects with chronic pain conditions, using omics.

Metabolic dysfunction-associated steatotic liver disease (MASLD)

Metabolic dysfunction-associated steatotic liver disease (MASLD) previously known as non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease which has become the most common liver disease affecting adults and children.

The Fredriksson Lab

The main challenge of addiction treatment is high relapse rates during abstinence. We use preclinical models to study the mechanisms and circuits that mediate opioid relapse and craving.

Emergency Medicine Research Center

The research and development unit of the Emergency Department at Linköping University Hospital was started in 2016. In 2021, the Emergency Department became Sweden's first university healthcare unit in emergency medicine.

Cardiovascular imaging and modeling - CIM

CIM:s tvärvetenskapliga forskningskluster syftar till att öka förståelsen för det kardiovaskulära systemet i hälsa och sjukdom genom utveckling och tillämpning av nya bildbaserade metoder för bedömning av funktion, hemodynamik och vävnadens karaktär.

The Johansson Capusan Lab

We explore genetic and environmental risk and follow clinical outcomes in addiction medicine using national and regional Swedish registers with the overall aim to improve healthcare for addiction.

The Barbier Lab

We explore the neural circuits and molecular mechanisms that underlie alcohol use- and anxiety disorders. Additionally, we examine potential common mechanisms that may link these two disorders.

The Szczot Lab

External stimuli in concert with internal state guide behaviors, moods and choices. Deciphering how sensory representation is altered by injury, might have major implications for the treatment of somatosensory dysfunctions like chronic pain.

The Heilig Translational Psychiatry Lab: Clinical group

We use brain imaging, behavior analysis and pharmacology to study how a breakdown of coping with stress and regulating negative emotions results in disorders such as depression, post-traumatic stress and addiction.

The Augier Lab

Addiction leads to a progressively increased choice of drugs over healthy rewards such as food and social interaction. We investigate the mechanisms and circuits driving individual variability to substance use disorder.

The Heilig Translational Psychiatry Lab: Preclinical group

We use animal models to discover molecular and neural mechanisms that cause a progression into alcohol addiction, and to identify novel targets for pharmacological addiction treatments.

Robust, Realistic and Reliable Measurements of Metabolism

New measuring techniques have always been one of the most important driving forces for medical development. The methods developed in this project could allow us to look further into the body: into the highly detailed metabolism of the human cells.

Lifestyle Intervention Implementation Research Group

We aim to develop, evaluate and implement behaviour change interventions that can contribute to an improved public health.

Interprofessional learning in simulation-based training for the healthcare professions

The overarching purpose of this project is to develop knowledge on how interprofessional collaboration in healthcare teams could be arranged and trained through simulation-based learning environments.

Cardiovascular Risk Factors in Patients with Type 2-diabetes - CARDIPP

The aim is to identify risk markers for cardiovascular disease to facilitate early and individually adjusted interventions in middle-aged men and women with Type 2-diabetes.

The added value of a behavioural medicine intervention, ECRA

The project "The role of a behavioural medicine intervention in physiotherapy for the effects of rehabilitation outcomes in exercise-based cardiac rehabilitation" - also called ECRA.

Physiotherapy - Epidemiology and Prevention

Our research focus is to improve this knowledge of injury and sickness in different populations, especially in sports and work related populations. Epidemiological registering of preventive and health ca interventions is another focus.

Cesar-Network

CESAR is a group of researchers that are working toward Collaboration and Exchange in Swedish cardiovascular cAring Research.

Sports Analytics

Sports analytics deals with using data related to sports events to obtain insights about the sport and its surroundings. The insights can relate to player and team performance, strategies, training, injuries, and rules of the game.

Learning Occupational Therapy Skills, LOTS

Physical activity and exercise in cardiovascular disease (PHYS-EX CVD)

The overall aim is to develop and evaluate methods and interventions with special focus on physical activity and exercise in cardiovascular disease.

Citizenship and Dementia

Citizenship and dementia is a research group that analyses how it is to be a citizen with dementia - from citizenship ideas, to welfare organisation, efforts and meetings with people with dementia, to the importance of civil society.

General Practice

Broad research with a patient-centred perspective. Research and teaching in general medicine affects many large patient groups and disease panoramas in primary care.

Haemostasis Research Group in Linköping

We study regulation of platelet activation and interaction with coagulation from biochemistry and genes to clinical studies on antithrombotic drugs in cardiovascular diseases and how covid-19 causes thrombosis. We also develop new diagnostic methods.

Talk about prognosis

It is important that patients with heart failure and family members know what they can expect in their future care, also in the last stages of life.

Interpretation in health care

Light is shed on the role of circumstances and organisational context to examine the constraints, conditions, methods and traditions to which interpreting is subject.

Rehabilitation medicine

Twincities Research Group - Social environment and health

The twin cities of Linköping and Norrköping are two equal sized cities in southeast Sweden. They are part of the same county council and have the same structure of health care. How could public health in two so similar cities be so different?

European Heart Failure Self-care Behaviour Scale

Self-care in heart failure, where the EHFScB scale can be used, refers to behaviours or measures that the patient himself performs with the aim of increasing life expectancy, health and well-being.

SSI – The school setting interview

SSI (its Swedish name is abbreviated BAS) is an interview instrument which, based on the student's perspective identifies the need of adaptation in school.

Technology and self care in cardiac patients

Technology can help patients to have better self-care, to be less dependent to health care providers and have a better quality of life.

Human Movement Science

We improve knowledge of movement system function in healthy as well as individuals with functional impairments due to sickness of injury. Our research utilizes methods for measuring and analyzing the mechanisms required for function and activity.

MRI-based Body Composition Analysis

Metabolic risk related to body-fat accumulation is strongly dependent on fat distribution. This project has developed a method for quantitative assessment of body composition that measures both fat distribution and muscle volume.

Graduate School in Health Professions Education

The purpose of this graduate school in medical education is to offer postgraduate training to strengthen and achieve higher quality in within educations in health and medicine offered at Linköping University, Stockholm University and KI.

Quantitative MRI of the Brain

Physiotherapeutic Diagnostics and Rehabilitation

We conduct clinical research on diagnostic methods and effects of interventions such as therapeutic exercise, manual therapies, pain management modalities as well as pedagogical and behavioural based management strategies.

Educational Equality for Children with Developmental Language Disorder. A Study of Goal Attainment, Experience and Participation

The project aims to generate knowledge that can be used to improve the organization of learning activities for children with developmental language disorder (DLD), as well as to improve the experience of school attendance among these children.

Centre for Medical Technology Assessment

We conduct method development, disseminate research findings and assess methods and procedures within healthcare with respect to medical, social, economical and ethical consequences.

Advanced CT Exams for Heart and Vessels

This flagship project combines mainly coronary artery morphology and cardiac function research with CT at CMIV.

Centre for Medical Humanities and Bioethics

We gather, strengthen, and develop research, teaching, and collaboration with the society around us, within the areas of medical humanities and bioethics.

LiU collaborates with the University of California in osteoporosis study

The fact that a common drug against osteoporosis can also cause bone fractures created major concern following a study at Linköping University. LiU will now lead the Swedish part of an international project to gain more knowledge about this.

The Buddy randomised factorial trial

A multiple lifestyle behaviour mHealth intervention targeting college and university students.

Talk about heart failure

In this research project, a communication tool has been developed which aims to facilitate communication about the heart failure trajectory between patients, their family members and health care professionals.

EpiChrom 2021

Welcome to EpiChrom 2021, Swedish Epigenetics and Chromatin Meeting. Organized by Linköping University on September 2nd to September 3rd, 2021.

Natural corollaries and recovery after acute Anterior Cruciate Ligament (ACL) injury – the NACOX cohort study protocol

Anterior cruciate ligament (ACL) injury can result in joint instability, decreased functional performance, reduced physical activity and quality of life, and an increased risk for post-traumatic osteoarthritis.

Research Focus Dermatology

The ultimate goal of the research is to increase the understanding of the underlying mechanisms of skin diseases, in order to facilitate the development of more specific treatments and clinical care.

Vascular Immunology Group

We want to understand why the immune system isn’t balanced in many with coronary heart disease to be able to tailor the treatment of the cause of the disease, rather than the symptoms.

Forskarskolan Nara vard

Registry-based projects in SWEDEHEART

A project from the PHYS-EX CVD group.

Better management of musculoskeletal conditions

Musculoskeletal disorders rank highest in the global disease burden. The purpose of our research is to evaluate and implement evidence-based care for musculoskeletal disorders.

M4-health: the basis for general AI in health care

In the VR funded project “M4-health: the basis for general AI in health care” we make way for a more general and flexible type of AI in health care.

Learning in virtual health environments

How can IT support learning across different virtual environments (visualisation, virtual patients and simulation) within healthcare education and practice?

The SUNRISE project

SUNRISE - International Surveillance Study of Movement Behaviours in the Early Years is a project initiated by the University of Wollongong, Australia. The project examines children's physical activity.

Wii-project

Playing Wii games can help patients with heart failure to improve their exercise capacity, their daily physical activity quality of life. In this study patients will be randomized into attention control or structured access to a Wii game computer

Disability in school

What obstacles are there in school? How do children with disabilities view participation? How does technology support influence school results? We develop the SSI interview instrument, in which children themselves identify their needs of adaptations.

Instruments for assessing work ability

The assessment instruments AWC, AWP, WEIS & WRI are used by county council, national, municipal and private rehabilitation actors in Sweden for the assessment of individuals’ work ability and for designing person-centred rehabilitation interventions.

Knee injuries in sports

Our research focus is on risk factors, treatment and consequences after sport injury, especially knee and anterior cruciate ligament (ACL) injury.

Can I manage this? – Technology, health and ageing among oldest-old

New products and technical systems are expected to affect older people’s independence and social relations. How do older people view this development, does technology use lead to a sense of security and the possibility of remaining at home?

RemindMe

RemindMe is a new web-based planning and reminder aid. We are developing and testing the new digital tool, which is a support for individuals to remember activities and plan their day-to-day life.

Patients in clinical care

This project aims to support individuals with chronic diseases to learn more about selfcare and lifestyle behaviour change.

Young adults

Interventions to promote healthy behaviours among young adults is a good investment. Therefore, these projects target high school and university students.

Interprofessional learning in practice

The project has a practice-oriented perspective on learning as embedded in the complexities of practices. An interactive approach comprising ethnographic field studies is applied.

The Remote Exercise SWEDEHEART study

The primary aim is to evaluate if remotely delivered exercise-based cardiac rehabilitation can increase the proportion of patients with a recent myocardial infarction to successfully complete an exercise-based cardiac rehabilitation programme.

The Research Group for Digital Health and Care

This research group is interdisciplinary and consists of nurses, psychologists, physicians, and other healthcare professionals.

Simulation of Cardiac Blood Flow from CT

Advanced CT creates amazing visualization of the beating heart. However, the complex interactions of blood flow are not fully reflected by these images. This project aims to extract blood flow data from CT images using image-based simulations.

Carotid plaque assessment

This project develops novel methods for better risk assessment of carotid plaque by focusing on plaque composition and blood flow parameters rather than level of vessel constriction.

Clinical Ophthalmic Research

Sight is our most important source of information about the world around us, and is the mind that engages most of the brain. Preserved vision is a basic prerequisite for maintaining one's independence in everyday activities, especially in old age.

Stressheart

The research group Stressheart has developed an analysis method where the stress hormone cortisol is measured from human hair to study stress levels several months back in time, like the annual rings on a tree.

Knowledge Driven Drug Development

In this project, financed by VR medicine’s investment in pharmacy, the researchers are working with AstraZeneca to develop a new type of knowledge driven drug development.

Participation in Later life - PiL

The research concerns everyday life and opportunities for activity and participation in society for different groups of older people. Issues of ageing, participation, remaining at home and technology use are all essential elements of the research.

Internet use and participation

How do young people with intellectual disabilities use internet to take part in everyday digital life and an ever more internet based society? We explores this question from the target group’s own perspective, using methods adapted for the purpose.

Treatment of meniscus injuries

Keyhole surgery has long been the most common treatment for suspected meniscus injury. But the benefits of the operation are now being questioned and instead replaced with training primarily for middle-aged and older people with knee pain.

HEART4FLOW

The objective of the HEART4FLOW project is to develop the next generation of methods for the non-invasive quantitative assessment of cardiac diseases and therapies by focusing on 4D blood flow dynamics.

Myocardial Adaptation in Aortic Valve Disease

Aortic valve disease can lead to strain on the left ventricle of the heart and ultimately heart failure. Our research aim for better diagnostics and treatment for these patients.

Surgical treatment of atrial fibrillation

Atrial fibrillation is common in patients scheduled for cardiac surgery. We study the impact of different ablation techniques on apoptosis, inflammatory response, atrial function and clinical outcome.

Simulation in Health Care - the simulation educator's perspective

We study pedagogical development of instructors in medical simulation over time, with focus on both individual and organisational development.

Mitral Valve Surgery

Mitral valve regurgitation is the most common indication for mitral valve surgery. A repair of the valve results in a more beneficial outcome than a replacement with a prosthesis.

Evaluation of Aortic valve interventions

In an observational cohort study we follow patients with aortic valve disease from evaluation through the surgery or catheter based intervention to one year follow up.

Suspected infections in frail elderly

Can new technology involving the elderly and their relatives lead to early detection of infection and reduce the number of hospital days?

Etiology and prevention of spinal deformities

The etiology of many spinal deformities are complex or even unknown. Genetics, muskuloskeletal structural integrity, biomechanical factors and neuromuscular functional impairments may be causal factors for spinal deformity.

Athletics Research Center

Athletics (track and field) is globally one of the most popular individual sports and the largest sport at the Olympic Games. The Athletics Research Center is a hub for international multi-disciplinary Athletics research.

Barnafrid

Barnafrid is a national knowledge center with the aim of assembling and disseminating knowledge about violence and other abuses against children. It is a government commission that was assigned Linköping University in 2015.

Effects of rTMS on alcohol use

Craving alcohol and an impaired ability to stop drinking despite adverse consequences are key features of alcohol addiction. This project aims to find a noninvasive brain stimulation method that can be used as treatment for addiction.

Diagnosis and rehabilitation for Whiplash Associated Disorders

Clinical and experimental rheumatology

A long-term ambition is to contribute to increased understanding of underlying mechanisms for the disease onset, progress and perceived quality of life in systemic inflammatory diseases, especially with regard to systemic lupus erythematosus (SLE)

Patients with elective surgery

A good health status before surgery decrease the risk for complications after surgery. Therefore, this project aims to support healthy lifestyle behaviours before surgery.

Individuals seeking help at primary healthcare centers

A great deal of the Swedish population has unhealthy lifestyle behaviours and this project focuses on patients in primary healthcare.

Preschool Children

Childhood obesity remains a significant global health challenge. This project aims to promote healthy food and physical activity habits among preschool children.

Maternal obesity and perinatal outcome

How does maternal obesity affect the course of labor? We have shown that obese women experience a longer dilation phase during childbirth. Does the same apply to women who, for various reasons, require labor induction?

Activity and severe multiple disabilities – Rett syndrome

The goal of our research is to increase knowledge about people with Rett syndrome and their everyday activities.

New possibilities with technology support in school

What obstacles and difficulties do pupils with different disabilities experience at school? How can we get them more involved and active? Through assessments using SSI, individually support measures and technology support the participation increases.

Vocational rehabilitation – assessment and intervention

The focus of the research field is work ability, and how this complex phenomenon can be assessed and understood as a basis for interventions.

Artificial heart pump with pulsatile flow

In collaboration with Scandinavian Real Heart we develop the surgical and aenesthesiological technique for implanting an artificial heart in patients with chronic heart failure.

Sexual counselling for cardiac patients

Patients with chronic disease might have questions about intimacy and sexual function. It is important that health care providers address these issues.

Ageing and participation among people with intellectual disabilities

Participation of people in all ages is one of the main goals in Swedish disability policy. This project aims to highlight and problematize ageing and participation among older people with intellectual disabilities living in Group homes.

Gastroviruses

Rotavirus and norovirus (the winter vomiting disease, “vinterkräksjuka”) are major causes of acute diarrhea worldwide. The underlying disease mechanisms are still unresolved.

TPMT nomenclature committee

Our aim is to maintain a common, logical nomenclature system for thiopurine methyltransferase (TPMT) alleles in humans.

Skin cancer prevention in primary care

DOHART (DOwnHeARTed)

An important purpose of the DOHART study is to improve the care and treatment of people with heart disease and depressive disorders using an internet-based self-help programme based on cognitive behavioural therapy (CBT).

Studies to improve survival and quality of life among women with gynaecological cancer

We want to improve the treatment for patients with gynaecological cancer with the aim of prolonging survival without causing short- and long-term side-effects affecting daily life activities.

Quantitative computed tomography for more accurate radiotherapy

We are developing quantitative image reconstruction methods with dual-energy computed tomography to measure the atomic composition of patient organs before radio therapy.

Optimizing X-ray imaging procedures

Optimising medical x-ray examination aims to find the settings on the x-ray unit that minimises the patient exposure while maintaining sufficient image quality.

Dosimetry in X-ray imaging

Modern X-ray procedures results in a considerable contribution to population doses from ionising radiation. We develop computer simulation models to facilitate more accurate calibration of radiation dosimetres to assess patient exposure.

Center for Systems Neurobiology

Center for Systems Neurobiology is a strategic effort from Linköping University (LiU) and Region Östergötland aimed at strengthening research within the medical field.

Support at school and the transition to upper secondary school, further studies and work

We look at the transition process from secondary to upper secondary school, further studies and/or work for young adults with neuropsychiatric disabilities.

Sleep Disorders

In my research group, we study brain function in narcolepsy and periodic idiopathic hypersomnia, the Kleine-Levin syndrome, in order to increase the understanding of the patients' symptoms and possibly reduce the time to diagnosis.

Functional brain imaging

In our research group, we use combined fMRI-EEG and mathematical modelling in studies of brain function related to different mental states e.g., sleep, wakefulness, meditation, and pain.

Mechanistic modelling of brain function

By mathematical modelling, we can test different hypotheses explaining brain function. We apply systems biology approaches to describe the mechanisms behind the neurovascular coupling measured in functional magnetic resonance imaging (fMRI).

Nordic Implementation Interest Group

Nordic Implementation is an interest group of researchers and practitioners, who are exploring and investigating issues concerning implementation of evidence-based practices and quality improvement in health and human services.

Implementation in health care and society

The research program Implementation aims to conduct high-quality interdisciplinary research and education to address important issues concerning implementation and research use in health care and society at large.

The Cardiodiet Trial

Is a Mediterranean diet with reduced carbohydrate content a better choice than traditional low-fat diet for patients with coronary heart disease?

Reactions and experiences of illness and poor health

An individual’s experience, reaction and management of symptoms, illness and poor health are dependent on the person being viewed from a holistic perspective.

Development of Nursing Science theory and methodology

To maintain high quality research and nursing care, it is important to develop theories and different concepts that are used in nursing care research.

Consequences of nursing care and treatment

Quality of life/health-related quality of life, self-care, symptom relief, recovery, functional status and complications are studied.

Prerequisites for health

Human resources for maintaining or recovering health, or accepting an altered life and health situation are studied.

Forum Scientium Graduate School

Graduate school Forum Scientium, a bridge between medicine, natural sciences and engineering, stimulates creativity and a common use of ideas, knowledge, and equipment.

Microbial pathogenisity in tuberculosis

Our research focuses on the beneficial role of innate immune cells and their cooperation for the control of Mtb during simultaneous co-infection.

Psychosocial Obstetrics and Reproduction

We study IVF, oocytes and sperm donation and surrogate motherhood – from the very first conversation at the clinic to follow up several years later.

Applied Auditory Research

The hearing science group at LiU conduct research in several areas such as hearing physiology, diagnosis of hearing loss, rehabilitation and intervention, hearing aids and cochlear implants, and digital signal processing.

Reproduction and Neuro Immunology

The general purpose of our research is to reveal mechanisms of immune tolerance in pregnancy and how failure of tolerance mechanisms can lead to pregnancy complications.

Oncopharmacology

Our research is within the field of Drug research and Onco-pharmacology. Our aim is to identify drugs with new mechanisms of action, and try to develop drug candidates for clinical use.

Importance of pharmacogenetics for individualising chemotherapy

In addition to cellular studies, we study TPMT and the various genetic variants using recombinant protein. We use biophysical techniques to study the difference in protein stability and drug affinity between TPMT and other genetic varieties.

Head and Neck Cancer

We aim to study the signaling pathways involved in response/resistance to cisplatin, cetuximab, and radiotherapy in order to find new predictive markers and new targets for therapy